IQMaxxing : A deep dive into Cerebrolysin.

[MaracasMogs]

Bbumpy

 

[Latinolooksmaxxer]

i was born with 165iq

 

[Copercel]

Hey guys, back with another high iq thread.
This time, I will be doing a deep dive into Cerebrolysin, a nootropic.

First of all, I want to precise that I am not a doctor. Any potential harm caused by the people viewing this thread were the only responsible for their harm.

For the people who will NOT read this thread, feel free to rep this thread and bump it.

Spoiler: What is Cerebrolysin ?

Cerebrolysin is a standardized, ultrafiltrate of porcine brain proteins
a mix of small peptides and free amino acids intended to mimic
endogenous neurotrophic factors. It’s given parenterally (IV or IM).
The manufacturer’s product monograph describes it as a
multimodal neuropeptide drug with rapid onset.

View attachment 4128886

Claimed mechanism of action: mimics neurotrophic growth factors
(BDNF, NGF-like effects), modulates neuroinflammation, reduces apoptosis,
stabilizes blood–brain barrier, promotes neuroplasticity and synaptogenesis
in animal models. There’s preclinical evidence of increased BDNF and
reduced neuronal death after insults.

Source for the highinhibs :
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2020.568813/full

Spoiler: Theory

There’s no strong, replicable RCT data showing robust cognitive enhancement
in healthy adults after Cerebrolysin courses. Old small volunteer studies
show acute EEG and short-term memory effects, but translating that
into sustained IQ-style gains or “super-learning” is unsupported.

So my theory is : Cerebrolysin could enhance the cognitive and parietal
fonction because of it's cerebral repairing properties.

Spoiler: What does it do ?

Neuroprotection & neurorestoration: multiple rodent models of ischemia,
TBI, and seizures show reduced infarct size, less neuronal death, and
improved behavioral outcomes after CBL; correlated with upregulation
of BDNF and other pro-survival signals. Mechanistically this looks
like trophic support + reduced excitotoxicity.

EEG / short-term memory effects in humans (early small study): old volunteer
studies showed dose-dependent EEG changes and some short-term memory improvement
under hyperventilation-induced ischemia modeling, hinting at acute CNS
electrophysiological effects. Not the same as proven long-term cognitive
enhancement in healthy people, but interesting

Conclusion : : This means cerebrolysin helps damaged neurons survive, repair, and make new connections.
I want to precise ht
That is why it could be great for IQMaxxing !

https://pubmed.ncbi.nlm.nih.gov/9700674/

Spoiler: Clinical Evidence

Here i will put multiple studies, showing brain "repair" after injury, trauma, etc.

This one is about traumatic brain injury :
https://www.mdpi.com/2076-3425/13/3/507

Dementia (Alzheimers and vascular dementia) :
https://pubmed.ncbi.nlm.nih.gov/19848437/

Depression, anxiety blud, consciousness recovery:
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.00803/full

https://pmc.ncbi.nlm.nih.gov/articles/PMC9147297/

Sadly, a study about healthy people taking cerebrolysin :

Dose-dependent effects of Cerebrolysin on EEG and short-term memory of healthy volunteers during control and hyperventilation induced cerebral ischemia - PubMed

Cerebrolysin, a peptidergic nootropic drug, was to be effective on learning and other cognitive functions in animal experiments as well as in clinical studies. Hyperventilation (HV) as a model of brain ischemia induces slowing of the EEG and cognitive impairment. The aim of this study was to...

pubmed.ncbi.nlm.nih.gov

Preclinical and small volunteer studies
suggest potential for short-term memory,
learning speed, and neuroplasticity enhancement.

it’s a mixture of peptides that mimics neurotrophic factors like BDNF and NGF,
which are literally the molecules responsible for brain growth and plasticity.
In stroke and TBI patients, Cerebrolysin has been shown to accelerate recovery
and improve functional outcomes, meaning it can repair and rewire damaged neural
circuits. In Alzheimer’s and vascular dementia, clinical trials report modest but real
cognitive improvements, which implies enhanced synaptic function even in aging,
diseased brains . Animal studies go further: it boosts hippocampal survival, reduces
oxidative stress, and increases synaptic density, all of which line
up with better memory and learning capacity.

Spoiler: Safety

When people bring up safety concerns with Cerebrolysin, the reality is that
it’s one of the cleaner compounds out there. Across dozens of clinical
trials in stroke, TBI, and dementia, adverse events were comparable to
placebo, usually just mild dizziness, headaches, or injection-site reactions.
Meta-analyses confirm that it does not increase serious adverse events, even
when used for weeks in vulnerable elderly patients. The one real risk is
hypersensitivity, with rare case reports of anaphylaxis, but these are
extremely uncommon given the thousands of patients treated.
Epilepsy and severe renal failure are listed as contraindications, which
makes sense since neurotrophic signaling can lower seizure threshold
and peptide clearance is reduced in kidney disease.
Importantly, trials in Alzheimer’s patients, who are some of the
most fragile subjects possible, still showed it was well tolerated for repeated
cycles. That means in a healthy brain with no comorbidities, the safety margin
is even better. Compare that to most “research chemicals” where long-term
toxicity is unknown Cerebrolysin already has decades of clinical use and
pharmacovigilance data. The takeaway is clear: aside from rare allergy events,
the risk profile is low, especially relative to the potential cognitive upside.

Spoiler: Cerebrolysin course

Let's play the safe card : do not make your own (seems obv but i'm serious )

the data from mild cognitive impairment trials looks good imo. In these studies, daily
5–10 mL intramuscular injections for 20–30 days led to noticeable improvements in :

-Mental clarity,
-Memory,
and cognitive function in general.


https://pubmed.ncbi.nlm.nih.gov/9700674/

Spoiler: Conclusion

In conclusion, cerebrolysin could actually be a cheat code for IQ,
since its brain repairing, neuron connecting, and memory improving
properties could really make a difference in someone's day to day life.

Spoiler: Tags

@Aryan Incel @vincentzygo @chadisbeingmade @SlayerJonas @lewunknownslayer55

​

Nice

 

[kranerman23123]

Cope & DNR. The only drugs that actually change your brain function long term, promote neurogenesis and actual neuro structural change for cognitive enhancement are classical psychedelics. Everything else is complete cope and doesnt come anywhere near the neurogenerative and neuroplastic affects as psychedelics particularly DMT.

 

[MaracasMogs]

Cope & DNR. The only drugs that actually change your brain function long term, promote neurogenesis and actual neuro structural change for cognitive enhancement are classical psychedelics. Everything else is complete cope and doesnt come anywhere near the neurogenerative and neuroplastic affects as psychedelics particularly DMT.

stay dumb brah

 

[MaracasMogs]

Nice

thanks, congrats for the vip

 

[Copercel]

thanks, congrats for the vip

I’ve had it for 2 months already

 

[MaracasMogs]

I’ve had it for 2 months already

You just didn’t put the effect so I didn’t see it

 

[MaracasMogs]

Bbumpy bump

 

[vincentzygo]

Bbumpy bump

Desperation

 

[PlzEndIt]

will read later

 

[vision_n]

huge mirin
haven't tagged me tho

 

[MaracasMogs]

huge mirin
haven't tagged me tho

did i say i would? i didn't remember sorry
you want to be tagged in my future threads?

 

[vision_n]

did i say i would? i didn't remember sorry
you want to be tagged in my future threads?

count me in

 

[MaracasMogs]

count me in

will do boss

 

[Spieldren]

Hey guys, back with another high iq thread.
This time, I will be doing a deep dive into Cerebrolysin, a nootropic.

First of all, I want to precise that I am not a doctor. Any potential harm caused by the people viewing this thread were the only responsible for their harm.

For the people who will NOT read this thread, feel free to rep this thread and bump it.

Spoiler: What is Cerebrolysin ?

Cerebrolysin is a standardized, ultrafiltrate of porcine brain proteins
a mix of small peptides and free amino acids intended to mimic
endogenous neurotrophic factors. It’s given parenterally (IV or IM).
The manufacturer’s product monograph describes it as a
multimodal neuropeptide drug with rapid onset.

View attachment 4128886

Claimed mechanism of action: mimics neurotrophic growth factors
(BDNF, NGF-like effects), modulates neuroinflammation, reduces apoptosis,
stabilizes blood–brain barrier, promotes neuroplasticity and synaptogenesis
in animal models. There’s preclinical evidence of increased BDNF and
reduced neuronal death after insults.

Source for the highinhibs :
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2020.568813/full

Spoiler: Theory

There’s no strong, replicable RCT data showing robust cognitive enhancement
in healthy adults after Cerebrolysin courses. Old small volunteer studies
show acute EEG and short-term memory effects, but translating that
into sustained IQ-style gains or “super-learning” is unsupported.

So my theory is : Cerebrolysin could enhance the cognitive and parietal
fonction because of it's cerebral repairing properties.

Spoiler: What does it do ?

Neuroprotection & neurorestoration: multiple rodent models of ischemia,
TBI, and seizures show reduced infarct size, less neuronal death, and
improved behavioral outcomes after CBL; correlated with upregulation
of BDNF and other pro-survival signals. Mechanistically this looks
like trophic support + reduced excitotoxicity.

EEG / short-term memory effects in humans (early small study): old volunteer
studies showed dose-dependent EEG changes and some short-term memory improvement
under hyperventilation-induced ischemia modeling, hinting at acute CNS
electrophysiological effects. Not the same as proven long-term cognitive
enhancement in healthy people, but interesting

Conclusion : : This means cerebrolysin helps damaged neurons survive, repair, and make new connections.
I want to precise ht
That is why it could be great for IQMaxxing !

https://pubmed.ncbi.nlm.nih.gov/9700674/

Spoiler: Clinical Evidence

Here i will put multiple studies, showing brain "repair" after injury, trauma, etc.

This one is about traumatic brain injury :
https://www.mdpi.com/2076-3425/13/3/507

Dementia (Alzheimers and vascular dementia) :
https://pubmed.ncbi.nlm.nih.gov/19848437/

Depression, anxiety blud, consciousness recovery:
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.00803/full

https://pmc.ncbi.nlm.nih.gov/articles/PMC9147297/

Sadly, a study about healthy people taking cerebrolysin :

Dose-dependent effects of Cerebrolysin on EEG and short-term memory of healthy volunteers during control and hyperventilation induced cerebral ischemia - PubMed

Cerebrolysin, a peptidergic nootropic drug, was to be effective on learning and other cognitive functions in animal experiments as well as in clinical studies. Hyperventilation (HV) as a model of brain ischemia induces slowing of the EEG and cognitive impairment. The aim of this study was to...

pubmed.ncbi.nlm.nih.gov

Preclinical and small volunteer studies
suggest potential for short-term memory,
learning speed, and neuroplasticity enhancement.

it’s a mixture of peptides that mimics neurotrophic factors like BDNF and NGF,
which are literally the molecules responsible for brain growth and plasticity.
In stroke and TBI patients, Cerebrolysin has been shown to accelerate recovery
and improve functional outcomes, meaning it can repair and rewire damaged neural
circuits. In Alzheimer’s and vascular dementia, clinical trials report modest but real
cognitive improvements, which implies enhanced synaptic function even in aging,
diseased brains . Animal studies go further: it boosts hippocampal survival, reduces
oxidative stress, and increases synaptic density, all of which line
up with better memory and learning capacity.

Spoiler: Safety

When people bring up safety concerns with Cerebrolysin, the reality is that
it’s one of the cleaner compounds out there. Across dozens of clinical
trials in stroke, TBI, and dementia, adverse events were comparable to
placebo, usually just mild dizziness, headaches, or injection-site reactions.
Meta-analyses confirm that it does not increase serious adverse events, even
when used for weeks in vulnerable elderly patients. The one real risk is
hypersensitivity, with rare case reports of anaphylaxis, but these are
extremely uncommon given the thousands of patients treated.
Epilepsy and severe renal failure are listed as contraindications, which
makes sense since neurotrophic signaling can lower seizure threshold
and peptide clearance is reduced in kidney disease.
Importantly, trials in Alzheimer’s patients, who are some of the
most fragile subjects possible, still showed it was well tolerated for repeated
cycles. That means in a healthy brain with no comorbidities, the safety margin
is even better. Compare that to most “research chemicals” where long-term
toxicity is unknown Cerebrolysin already has decades of clinical use and
pharmacovigilance data. The takeaway is clear: aside from rare allergy events,
the risk profile is low, especially relative to the potential cognitive upside.

Spoiler: Cerebrolysin course

Let's play the safe card : do not make your own (seems obv but i'm serious )

the data from mild cognitive impairment trials looks good imo. In these studies, daily
5–10 mL intramuscular injections for 20–30 days led to noticeable improvements in :

-Mental clarity,
-Memory,
and cognitive function in general.


https://pubmed.ncbi.nlm.nih.gov/9700674/

Spoiler: Conclusion

In conclusion, cerebrolysin could actually be a cheat code for IQ,
since its brain repairing, neuron connecting, and memory improving
properties could really make a difference in someone's day to day life.

Spoiler: Tags

@Aryan Incel @vincentzygo @chadisbeingmade @SlayerJonas @lewunknownslayer55

​

good thread but conclusion sounds like some 8th grader chatgpt shit

 

[CalulArgintiu59]

Mirin thread, if cerebrolasyn were to be in pill form, I think everybody would take it

 

[MaracasMogs]

Mirin thread, if cerebrolasyn were to be in pill form, I think everybody would take it

Yeah me too

 

[MaracasMogs]

good thread but conclusion sounds like some 8th grader chatgpt shit

Yeah jfl I did the conclusion with it tbh

 

[jeoyw9192]

did i say i would? i didn't remember sorry
you want to be tagged in my future threads?

Tag me too

 

[why not me?]

A

 

[Its_over_gooner]

Hey guys, back with another high iq thread.
This time, I will be doing a deep dive into Cerebrolysin, a nootropic.

First of all, I want to precise that I am not a doctor. Any potential harm caused by the people viewing this thread were the only responsible for their harm.

For the people who will NOT read this thread, feel free to rep this thread and bump it.

Spoiler: What is Cerebrolysin ?

Cerebrolysin is a standardized, ultrafiltrate of porcine brain proteins
a mix of small peptides and free amino acids intended to mimic
endogenous neurotrophic factors. It’s given parenterally (IV or IM).
The manufacturer’s product monograph describes it as a
multimodal neuropeptide drug with rapid onset.

View attachment 4128886

Claimed mechanism of action: mimics neurotrophic growth factors
(BDNF, NGF-like effects), modulates neuroinflammation, reduces apoptosis,
stabilizes blood–brain barrier, promotes neuroplasticity and synaptogenesis
in animal models. There’s preclinical evidence of increased BDNF and
reduced neuronal death after insults.

Source for the highinhibs :
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2020.568813/full

Spoiler: Theory

There’s no strong, replicable RCT data showing robust cognitive enhancement
in healthy adults after Cerebrolysin courses. Old small volunteer studies
show acute EEG and short-term memory effects, but translating that
into sustained IQ-style gains or “super-learning” is unsupported.

So my theory is : Cerebrolysin could enhance the cognitive and parietal
fonction because of it's cerebral repairing properties.

Spoiler: What does it do ?

Neuroprotection & neurorestoration: multiple rodent models of ischemia,
TBI, and seizures show reduced infarct size, less neuronal death, and
improved behavioral outcomes after CBL; correlated with upregulation
of BDNF and other pro-survival signals. Mechanistically this looks
like trophic support + reduced excitotoxicity.

EEG / short-term memory effects in humans (early small study): old volunteer
studies showed dose-dependent EEG changes and some short-term memory improvement
under hyperventilation-induced ischemia modeling, hinting at acute CNS
electrophysiological effects. Not the same as proven long-term cognitive
enhancement in healthy people, but interesting

Conclusion : : This means cerebrolysin helps damaged neurons survive, repair, and make new connections.
I want to precise ht
That is why it could be great for IQMaxxing !

https://pubmed.ncbi.nlm.nih.gov/9700674/

Spoiler: Clinical Evidence

Here i will put multiple studies, showing brain "repair" after injury, trauma, etc.

This one is about traumatic brain injury :
https://www.mdpi.com/2076-3425/13/3/507

Dementia (Alzheimers and vascular dementia) :
https://pubmed.ncbi.nlm.nih.gov/19848437/

Depression, anxiety blud, consciousness recovery:
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.00803/full

https://pmc.ncbi.nlm.nih.gov/articles/PMC9147297/

Sadly, a study about healthy people taking cerebrolysin :

Dose-dependent effects of Cerebrolysin on EEG and short-term memory of healthy volunteers during control and hyperventilation induced cerebral ischemia - PubMed

Cerebrolysin, a peptidergic nootropic drug, was to be effective on learning and other cognitive functions in animal experiments as well as in clinical studies. Hyperventilation (HV) as a model of brain ischemia induces slowing of the EEG and cognitive impairment. The aim of this study was to...

pubmed.ncbi.nlm.nih.gov

Preclinical and small volunteer studies
suggest potential for short-term memory,
learning speed, and neuroplasticity enhancement.

it’s a mixture of peptides that mimics neurotrophic factors like BDNF and NGF,
which are literally the molecules responsible for brain growth and plasticity.
In stroke and TBI patients, Cerebrolysin has been shown to accelerate recovery
and improve functional outcomes, meaning it can repair and rewire damaged neural
circuits. In Alzheimer’s and vascular dementia, clinical trials report modest but real
cognitive improvements, which implies enhanced synaptic function even in aging,
diseased brains . Animal studies go further: it boosts hippocampal survival, reduces
oxidative stress, and increases synaptic density, all of which line
up with better memory and learning capacity.

Spoiler: Safety

When people bring up safety concerns with Cerebrolysin, the reality is that
it’s one of the cleaner compounds out there. Across dozens of clinical
trials in stroke, TBI, and dementia, adverse events were comparable to
placebo, usually just mild dizziness, headaches, or injection-site reactions.
Meta-analyses confirm that it does not increase serious adverse events, even
when used for weeks in vulnerable elderly patients. The one real risk is
hypersensitivity, with rare case reports of anaphylaxis, but these are
extremely uncommon given the thousands of patients treated.
Epilepsy and severe renal failure are listed as contraindications, which
makes sense since neurotrophic signaling can lower seizure threshold
and peptide clearance is reduced in kidney disease.
Importantly, trials in Alzheimer’s patients, who are some of the
most fragile subjects possible, still showed it was well tolerated for repeated
cycles. That means in a healthy brain with no comorbidities, the safety margin
is even better. Compare that to most “research chemicals” where long-term
toxicity is unknown Cerebrolysin already has decades of clinical use and
pharmacovigilance data. The takeaway is clear: aside from rare allergy events,
the risk profile is low, especially relative to the potential cognitive upside.

Spoiler: Cerebrolysin course

Let's play the safe card : do not make your own (seems obv but i'm serious )

the data from mild cognitive impairment trials looks good imo. In these studies, daily
5–10 mL intramuscular injections for 20–30 days led to noticeable improvements in :

-Mental clarity,
-Memory,
and cognitive function in general.


https://pubmed.ncbi.nlm.nih.gov/9700674/

Spoiler: Conclusion

In conclusion, cerebrolysin could actually be a cheat code for IQ,
since its brain repairing, neuron connecting, and memory improving
properties could really make a difference in someone's day to day life.

Spoiler: Tags

@Aryan Incel @vincentzygo @chadisbeingmade @SlayerJonas @lewunknownslayer55

​

tldr a letter, brain cancer sppedrun, no? (im lowiq)

 

[MaracasMogs]

Tag me too

Will do

 

[MaracasMogs]

im lowiq