Axton
Bronze
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- Dec 1, 2025
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I read in this post that it's better to use PBS instead of bac water, so I asked DeepSeek because I wanted to know more and it told me that using a multi-dose bottle of standard PBS for injections multiple times is unsafe because it lacks preservatives to stop bacterial growth. Every time you puncture the bottle to reconstitute another vial, in my case, a kit of 100mg vials, I would have to puncture it 10 times so after the first puncture it wouldn't be sterile anymore and everytime I need to reconstitute another vial I risk introducing bacteria that can multiply in the solution which can lead to serious skin infections, abscesses, or even life-threatening sepsis. Unlike bac water, which contains alcohol to kill microbes, standard PBS is designed for single-use laboratory work, not multi-dose injections. The solution for this that I found is to instead get a 5 or 10ml vial of single-use PBS for every vial (which is impossible to find), instead of a 100ml bottle of PBS that you use repeatedly for every vial, or just use the whole 100ml and reconstitute every vial at once, which will almost certainly degrade it.
So, for anyone who did reconstitute with PBS, how did it go? Let me know how true what I stated above is or if I'm wrong.
So, for anyone who did reconstitute with PBS, how did it go? Let me know how true what I stated above is or if I'm wrong.
