Is this a good stack for bone growth?

[childishkillah]

All androgens fuck up bone remodeling including when placed under load lol look into ar competing for nucleus transcription with runX2 and b catetin via depleting CBP and p300 stop promoting AAS cod periosteal apposition growth especially ones that have high ar binding affinity

Is proved that androgens give a postive outcome in the RUNx2 preventing overexpression and thus excesive bone reabsorption. Androgens also give a positive outcome in the ẞ-Catetin pathway trought non-genomic responses. AR agonism increases phosphorylation of GSK-3B, androgens increases cytosolic B-catenin inhibited by GSK-3B.

 

[user71636274916194]

Is proved that androgens give a postive outcome in the RUNx2 preventing overexpression and thus excesive bone reabsorption. Androgens also give a positive outcome in the ẞ-Catetin pathway trought non-genomic responses. AR agonism increases phosphorylation of GSK-3B, androgens increases cytosolic B-catenin inhibited by GSK-3B.

Yet they arko in bone shows no differences and if u use ur brain u can realise bc theu compete for CBP and p300 with both b catetine and runX2 the Increse in the studies can just be due to the cell not being able to use them also no not all lol most of the bike anabolism that comes from ar is bc of e2 ( since most study use aromitisble roids ) hence Why we see when we administer testo and it can’t convert to e2 or actually up regulates sots even more

 

[user71636274916194]

Yet they arko in bone shows no differences and if u use ur brain u can realise bc theu compete for CBP and p300 with both b catetine and runX2 the Increse in the studies can just be due to the cell not being able to use them also no not all lol most of the bike anabolism that comes from ar is bc of e2 ( since most study use aromitisble roids ) hence Why we see when we administer testo and it can’t convert to e2 or actually up regulates sots even more

Is proved that androgens give a postive outcome in the RUNx2 preventing overexpression and thus excesive bone reabsorption. Androgens also give a positive outcome in the ẞ-Catetin pathway trought non-genomic responses. AR agonism increases phosphorylation of GSK-3B, androgens increases cytosolic B-catenin inhibited by GSK-3B.

https://pmc.ncbi.nlm.nih.gov/articles/PMC4871247/ 0 changes in bones