cemkii
Bloatcel
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ISOTRETINOIN
What is isotretinoin?
Isotretinoin is a powerful prescription only vitamin a derived retinoid. It is used to combat severe acne. This is the most overkill treatment for acne and guaranteed to clear your acne. Please do not use tretinoin or taz or any other cope this is systemic and superior.
How it works?
Isotretinoin works by shrinking the sebaceous glands, unclogging pores, reducing inflammation, and lowering bacteria that causes acne. It is most effective in cystic acne, papules, and blackheads, it is less effective in reduction of jawline acne and milder acne. Its effects last even after stopping and works cumulatively so dose is finalized early on but split across days. However effects are not permanent further side effects will be addressed.
Dosage and timing:
Dosage of isotretinoin is calculated by your body weight 120-150mg per kg of body weight for those outside of Europe 54-68 mg per lb of body weight. It does not matter when it is taken as the product works by accumulation not day to day difference as long as you are consistent over days you are fine. I prefer the long approach to not risk side effects however as long as you dont go over 80mg a day you are fine 10mg is too low start at 20mg its a waste of time. State of dose does matter in isotretinoin although older studies had preferred isotretinoin to be taken with a meal that includes fat newer studies show higher absorption via a fasted state. see below:
Where to purchase?
Isotretinoin is on the cheaper side and is widely available through many sources. I had purchased mine via indiamart paid £120 for the whole supply. It is unlikely that you will find counterfeit isotretinoin this way, however, still is possible make sure they are trusted and have certificates, and obviously packaging has not been tampered with.
Alternatives:
For all you topical nerds that are scared of a pill, other forms of retinoids are available however they are not systemic such as tretinoin, differin and Tazarotene. However all of these just cause flaking and texture refinement does nothing for more severe acne.
Side effects!! (read first grey)
Side effects include dryness, retinoid flare, dermatitis, nosebleeds, bleeding/damaged lips, dry eyes, sun sensitivity, sensitivity to alcohol, liver strain, avoid any lasers or acids on face, dull skin from lack of sebum. Note that skincare must be accounted for; Do not overwash, use a good moisturizer and spf everyday
Now how do we fix these:
Sun sensitivty: spf 50 daily even indoors
nosebleeds: isotonic saline spray or naseptin
damaged lips: reduce dose and/or humectant based lip balm
dry eyes: artificial tears especially if you use contacts
dermatitis: lower dose or b5 balm or steroid or reduce exposure to heat/sun
Liver strain: just dont drink shouldnt be anyways
try not to get pregnant as well i guess??
Post isotretinoin:
Now you can fix that dull skin that isotretinoin caused. azelaic acid can be introduced treat it as a topical retinoid or just jump straight to co2 laser works amazing here to clear any scars, pih, or post inflammation in the face (bit overkill yes but worth it). However it is recommended a few months wait after stopping as isotretinoin does affect healing so could make it worse although newer studies say it is irrelevant. It takes about 3-6 months off isotretinoin to see your skin alive again annoying but at least no acne is present.
TL;DR
Isotretinoin works wonders no need to cope with diet and cutting sugar.
just follow simple things tired of seeing people fucking up the basics in this. Can give more personalized advice just drop a reply ive tried tretinoin, azelaic, co2, differin, and isotretinoin.
What is isotretinoin?
Isotretinoin is a powerful prescription only vitamin a derived retinoid. It is used to combat severe acne. This is the most overkill treatment for acne and guaranteed to clear your acne. Please do not use tretinoin or taz or any other cope this is systemic and superior.
How it works?
Isotretinoin works by shrinking the sebaceous glands, unclogging pores, reducing inflammation, and lowering bacteria that causes acne. It is most effective in cystic acne, papules, and blackheads, it is less effective in reduction of jawline acne and milder acne. Its effects last even after stopping and works cumulatively so dose is finalized early on but split across days. However effects are not permanent further side effects will be addressed.
Dosage and timing:
Dosage of isotretinoin is calculated by your body weight 120-150mg per kg of body weight for those outside of Europe 54-68 mg per lb of body weight. It does not matter when it is taken as the product works by accumulation not day to day difference as long as you are consistent over days you are fine. I prefer the long approach to not risk side effects however as long as you dont go over 80mg a day you are fine 10mg is too low start at 20mg its a waste of time. State of dose does matter in isotretinoin although older studies had preferred isotretinoin to be taken with a meal that includes fat newer studies show higher absorption via a fasted state. see below:
Where to purchase?
Isotretinoin is on the cheaper side and is widely available through many sources. I had purchased mine via indiamart paid £120 for the whole supply. It is unlikely that you will find counterfeit isotretinoin this way, however, still is possible make sure they are trusted and have certificates, and obviously packaging has not been tampered with.
Alternatives:
For all you topical nerds that are scared of a pill, other forms of retinoids are available however they are not systemic such as tretinoin, differin and Tazarotene. However all of these just cause flaking and texture refinement does nothing for more severe acne.
Side effects!! (read first grey)
Side effects include dryness, retinoid flare, dermatitis, nosebleeds, bleeding/damaged lips, dry eyes, sun sensitivity, sensitivity to alcohol, liver strain, avoid any lasers or acids on face, dull skin from lack of sebum. Note that skincare must be accounted for; Do not overwash, use a good moisturizer and spf everyday
Now how do we fix these:
Sun sensitivty: spf 50 daily even indoors
nosebleeds: isotonic saline spray or naseptin
damaged lips: reduce dose and/or humectant based lip balm
dry eyes: artificial tears especially if you use contacts
dermatitis: lower dose or b5 balm or steroid or reduce exposure to heat/sun
Liver strain: just dont drink shouldnt be anyways
try not to get pregnant as well i guess??
Post isotretinoin:
Now you can fix that dull skin that isotretinoin caused. azelaic acid can be introduced treat it as a topical retinoid or just jump straight to co2 laser works amazing here to clear any scars, pih, or post inflammation in the face (bit overkill yes but worth it). However it is recommended a few months wait after stopping as isotretinoin does affect healing so could make it worse although newer studies say it is irrelevant. It takes about 3-6 months off isotretinoin to see your skin alive again annoying but at least no acne is present.
TL;DR
Isotretinoin works wonders no need to cope with diet and cutting sugar.
just follow simple things tired of seeing people fucking up the basics in this. Can give more personalized advice just drop a reply ive tried tretinoin, azelaic, co2, differin, and isotretinoin.



