LAST HOPE FOR GROWTH PLATES? MEGATHREAD. (HIGH IQ)

ND jainn

ND jainn

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EXPLAINING
KY19382 – currently the most potent Wnt/β pathway activator, inhibiting the CXXC5 protein, which is responsible for the aging of growth plate cartilage during puberty. Inhibition of CXXC5 triggers rapi differentiation of longitudinal bone growth and slows the closure of growth plates by almost half. (which allows us to remove the restriction)

1000001688



STUDY #1
The most interesting and important study was where KY19382 suppressed CXXC5 and activated Wnt/β-catenin.
In the same study, KY19382 showed an increase in tibia size with a dose of 0.1 mg/kg body weight. This is an incredible result and potential for height gain. A daily increase in the length of the growth plate.
It also affects COL2A1, RUNX2 and MMP13 in the growth plates.

1000001691



STUDY #2
A functionally improved indirubin derivative, KY19382, elongated tibial length through delayed senescence and further activation of the growth plate in adolescent mice. Collectively, our findings reveal an important role for CXXC5 as a suppressor of longitudinal bone growth involving growth plate activity.

1000001694



CONCLUSION
To sum it up, we can say with confidence that KY19382 Ideal for stack to increase bone length. It is very cheap (if you know where to buy) and extremely accessible.
The recommended dose is 705mcg/1g per kg of body weight.
As long as your growth plates are open, this will be the ideal option for increasing length.
 

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Last edited:
  • +1
Reactions: copedcel and mistermogsalot
grown ahh man talking bout sum hi
 
EXPLAINING
KY19382 – currently the most potent Wnt/β pathway activator, inhibiting the CXXC5 protein, which is responsible for the aging of growth plate cartilage during puberty. Inhibition of CXXC5 triggers rapi differentiation of longitudinal bone growth and slows the closure of growth plates by almost half. (which allows us to remove the restriction)

View attachment 5305879


STUDY #1
The most interesting and important study was where KY19382 suppressed CXXC5 and activated Wnt/β-catenin.
In the same study, KY19382 showed an increase in tibia size with a dose of 0.1 mg/kg body weight. This is an incredible result and potential for height gain. A daily increase in the length of the growth plate.
It also affects COL2A1, RUNX2 and MMP13 in the growth plates.

View attachment 5305881


STUDY #2
A functionally improved indirubin derivative, KY19382, elongated tibial length through delayed senescence and further activation of the growth plate in adolescent mice. Collectively, our findings reveal an important role for CXXC5 as a suppressor of longitudinal bone growth involving growth plate activity.

View attachment 5305883


CONCLUSION
To sum it up, we can say with confidence that KY19382 Ideal for stack to increase bone length. It is very cheap (if you know where to buy) and extremely accessible.
The recommended dose is 705mcg/1g per kg of body weight.
As long as your growth plates are open, this will be the ideal option for increasing length.
cool thread i skimmed through it and read conclusion
 
  • +1
Reactions: ND jainn
EXPLAINING
KY19382 – currently the most potent Wnt/β pathway activator, inhibiting the CXXC5 protein, which is responsible for the aging of growth plate cartilage during puberty. Inhibition of CXXC5 triggers rapi differentiation of longitudinal bone growth and slows the closure of growth plates by almost half. (which allows us to remove the restriction)

View attachment 5305879


STUDY #1
The most interesting and important study was where KY19382 suppressed CXXC5 and activated Wnt/β-catenin.
In the same study, KY19382 showed an increase in tibia size with a dose of 0.1 mg/kg body weight. This is an incredible result and potential for height gain. A daily increase in the length of the growth plate.
It also affects COL2A1, RUNX2 and MMP13 in the growth plates.

View attachment 5305881


STUDY #2
A functionally improved indirubin derivative, KY19382, elongated tibial length through delayed senescence and further activation of the growth plate in adolescent mice. Collectively, our findings reveal an important role for CXXC5 as a suppressor of longitudinal bone growth involving growth plate activity.




CONCLUSION
To sum it up, we can say with confidence that KY19382 Ideal for stack to increase bone length. It is very cheap (if you know where to buy) and extremely accessible.
The recommended dose is 705mcg/1g per kg of body weight.
As long as your growth plates are open, this will be the ideal option for increasing length.
interesting
 
  • +1
Reactions: ND jainn
my growth plates closed at 14
 
EXPLAINING
KY19382 – currently the most potent Wnt/β pathway activator, inhibiting the CXXC5 protein, which is responsible for the aging of growth plate cartilage during puberty. Inhibition of CXXC5 triggers rapi differentiation of longitudinal bone growth and slows the closure of growth plates by almost half. (which allows us to remove the restriction)

View attachment 5305879


STUDY #1
The most interesting and important study was where KY19382 suppressed CXXC5 and activated Wnt/β-catenin.
In the same study, KY19382 showed an increase in tibia size with a dose of 0.1 mg/kg body weight. This is an incredible result and potential for height gain. A daily increase in the length of the growth plate.
It also affects COL2A1, RUNX2 and MMP13 in the growth plates.

View attachment 5305881


STUDY #2
A functionally improved indirubin derivative, KY19382, elongated tibial length through delayed senescence and further activation of the growth plate in adolescent mice. Collectively, our findings reveal an important role for CXXC5 as a suppressor of longitudinal bone growth involving growth plate activity.




CONCLUSION
To sum it up, we can say with confidence that KY19382 Ideal for stack to increase bone length. It is very cheap (if you know where to buy) and extremely accessible.
The recommended dose is 705mcg/1g per kg of body weight.
As long as your growth plates are open, this will be the ideal option for increasing length.
Nice :feelsyay:
 
What’s the evidence this translates beyond adolescent mice into human height gain?
 

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