Letrozole and bone smashing

v8sandweights

v8sandweights

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Has anyone here bonesmashed a lot while on 2.5 letrozole a day ?

Asking cause I am but am just worried about theoretical bone resorption and loss of projection through the low estrogen mechanism that increases osteoclast activity while inhibiting osteoblasts which could in theory mean that the micro fractures in the bone then cause resorption as the osteoclasts create an acidic micro environment which essentially swallows the bone and gets rid of it losing projection

Now this is just a theoretical nightmare I have of losing bone projection but the science kinda makes sense, so just wondering if anyone here was on letrozole and smashed for a long time and is fine still so I can rest assured. Or perhaps anyone high iq which can pitch in
 
  • Hmm...
Reactions: wii and lowdimotrucel
Im on letrozole as well and this is something I’ve noticed while bonesmashing chin over the months. I’ve lost a slight amount of chin projection.
 

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