Managing Estrogen on Cycle and Proper AI Use (High IQ ROIDERS GTFIH)

[BR32]

Basic Pharmacology ​

Testosterone regardless of whether it is exogenous or endogenous gets converted into estradiol by the aromatase enzyme.

This is natural and beneficial-moderate E2 levels are essential for

• Muscle growth
• Joint lubrication
• LIbido and erectile function
• Mood stability
• Neuroprotection

However excess aromatization (especially from spikes in your test) can cause all of those nasty estrogenic side effects we all know

• Puffy nips or gyno​
• Bloating and excess water retention​
• Mood swings​
• Fatigue​

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So you decided to run the common beginner cycle of 500 test e pinning 2x/week and 6.25mg aromasin EOD and now you’re wondering why you feel like shit a few weeks in despite "controlling your estrogen" with an AI.

The problem with that is that aromatization is not linear

Most guys assume more testosterone → proportionally more estrogen → need tons of AI

Thats wrong
Aromatase is rate limited

Once you flatten testosterone peaks E2 production stabilizes

So nuking aromatase repeatedly with high does AI use overshoots massively.

In fact low E2 is actually worse than moderately high E2 in most men
From an anabolic and looksmaxxing perspective tanked E2 is a disaster

When we tank E2 here is what happens
MPS goes down, IGF 1 signaling goes down, your libido tanks, your lipids get fucked, etc​

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Managing Your Estrogen ​

The problem with many of the cookie cutter cycles that get prescribed on .org are that they suck at actually managing your estrogen properly and avoiding uncessecary sides effects. Here's is what you should actually do to properly manage E2.

• Pin every single day or at least every other day (This reduces aromatization compared to injecting once or twice a week when you spike your blood levels dramatically --> more aromatization) Low dose injections flatten the curve so when running a cycle like 250 or 300 test most people won't even need to use an AI)​
• Don't use an AI "just in case" what you are doing is tanking your E2 without bloodwork and thats gonna make you depressed, have ED, and you'll have poor anabolism.​
• Start your cycle with no AI​
• Monitor symptoms weekly puffy nips? Possible gyno. Lots of water retention? Thats probably elevated E2.​
• GET YOUR BLOODWORK DONE​
• Only add an AI if you absolutely need it: Arimidex start at 0.125-0.25mg 2x/week. Aromasin 6.25-12.5mg 2x/week.​
• Get lean-body fat increases aromatization​
• If you get gyno get on raloxifene ASAP (I recommend buying before you start your cycle)​

---

So you crashed your E2

Symptoms of crashed E2 include

Joint pain, zero libido, flat mood, dry skin, and brain fog, many misattribute these to high E2 or the gear itself.

If this happens stop AI use immediately and wait 5-10 days for low E2 sides to go away then reassess​

Example Protocol
Test E 300mg/week, pinned daily with a slin pin (43mg/day)
No AI at start
Monitor symptoms and bloods
Add Aromasin at low dose if needed
Keep water and sodium consistent
Track weight and bloating

Takeaways
Estrogen is your friend in the right range
Daily pinning is essential
AI use should be a last resort not a default
Stay lean, do bloodwork, optimize ​

 

[BR32]

Bump

 

[flows5991]

good thread

 

[flows5991]

@Aryan Incel @decadouche57

 

[BR32]

good thread

thanks

 

[vision_n]

Great structuring for <500 user

Good post

 

[BR32]

Great structuring for <500 user

Good post

I've seen too many wall of texts I had to make something accessible and digestible especially when its this important

 

[Tensor]

Good thread

 

[harmonytingfam]

water but decent info for newbies

 

[BR32]

water but decent info for newbies

that was the idea I just seen to many people taking 12.5mg aromasin EOD

 

[Aryan Incel]

Good thread