Deleted member 2621
Kortajarena lurking
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Could this maybe also work in older people?
"3.2. Low-Intensity Pulsed Ultrasound
Low-intensity pulsed ultrasound (LIPUS) produces mechanical waves that propagate through biological tissues at a pulse frequency of 1.5 MHz with a pulse repetition frequency of 1 kHz. At an output power of 30 mW/cm2, LIPUS can stimulate tissue growth without heating [15, 16]. A daily treatment with LIPUS for 20 minutes has been established as a favorable treatment modality in the field of orthopedics [36–39]. This treatment protocol has been found to stimulate bone healing after fracture in a variety of human and animal models by promoting new vascularization and bone formation [35–37]. Also, this technique has been applied successfully to promote growth and healing after distraction (i.e., excessive separation of bony segments) of the tibia in a rabbit model and after distraction of the callus [36, 39]. Daily direct application of LIPUS for 4 weeks also stimulated mandibular bone growth in rats and rabbits [22, 23]. However, achieving similar results in monkeys required four months of treatment [40] and about a year in humans (when combined with FAs) [41] (Figure 1). Such long periods of daily application of LIPUS are challenging and highly demanding for a clinical implementation. Thus, the development of an approach to boost the stimulatory effect of LIPUS on bone growth is necessary."
"3.2. Low-Intensity Pulsed Ultrasound
Low-intensity pulsed ultrasound (LIPUS) produces mechanical waves that propagate through biological tissues at a pulse frequency of 1.5 MHz with a pulse repetition frequency of 1 kHz. At an output power of 30 mW/cm2, LIPUS can stimulate tissue growth without heating [15, 16]. A daily treatment with LIPUS for 20 minutes has been established as a favorable treatment modality in the field of orthopedics [36–39]. This treatment protocol has been found to stimulate bone healing after fracture in a variety of human and animal models by promoting new vascularization and bone formation [35–37]. Also, this technique has been applied successfully to promote growth and healing after distraction (i.e., excessive separation of bony segments) of the tibia in a rabbit model and after distraction of the callus [36, 39]. Daily direct application of LIPUS for 4 weeks also stimulated mandibular bone growth in rats and rabbits [22, 23]. However, achieving similar results in monkeys required four months of treatment [40] and about a year in humans (when combined with FAs) [41] (Figure 1). Such long periods of daily application of LIPUS are challenging and highly demanding for a clinical implementation. Thus, the development of an approach to boost the stimulatory effect of LIPUS on bone growth is necessary."
