MSM Side effects and concerns

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With MSM, especially if you megadose it. It can cause bad side effects if your diet and other supplementation doesent support it. Basically, if depletes lots of the metals in our body, so you need to supplement choline (eggs), selenium, molbydenum, zinc, and copper. MSM can decrease their levels and possibly fuck you up. You should also supplement niacin because msm results in a build up of methyl groups and niacin helps clear them. VIt c as well and you needs magnesium glycine cause its a precursor in the lightening reactions for msm. Changes in the levels of anything will screw you up. Ive been on msm 4g+ for a six weeks now and now bad side effects at all, only lightening, Would not reccomend eating like 10g tho thats crazy. Anyone had any side effects?
 
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@MEGA CHAD I take 10g
 
HimmyButler said:
With MSM, especially if you megadose it. It can cause bad side effects if your diet and other supplementation doesent support it. Basically, if depletes lots of the metals in our body, so you need to supplement choline (eggs), selenium, molbydenum, zinc, and copper. MSM can decrease their levels and possibly fuck you up. You should also supplement niacin because msm results in a build up of methyl groups and niacin helps clear them. VIt c as well and you needs magnesium glycine cause it’s a precursor in the lightening reactions for msm. Changes in the levels of anything will screw you up. Ive been on msm 4g+ for a six weeks now and now bad side effects at all, only lightening, Would not reccomend eating like 10g tho thats crazy. Anyone had any side effects?
Click to expand...
Interesting, didn’t know this. But I imagine this will only be a real problem at higher dosages. 3-4g or less should be fine.
 
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Unsh said:
@MEGA CHAD I take 10g
Click to expand...
I took 10g daily for 4 months and I didn't feel any type of side effects, I must stress that I also took vitamin d3+k2, vitamin C, NAC, I also took compounds for Heightmaxxing.

In a few months I will return to MSM megadose together with GH and IGF1 Lr3
 
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MEGA CHAD said:
I took 10g daily for 4 months and I didn't feel any type of side effects, I must stress that I also took vitamin d3+k2, vitamin C, NAC, I also took compounds for Heightmaxxing.

In a few months I will return to MSM megadose together with GH and IGF1 Lr3
Click to expand...

what would the purpose of msm be in your stack? I dropped it off of mine cuz they said all things regarding methylation were false.
 
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For what purpose are you taking msm ?
 
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Splinter901 said:
what would the purpose of msm be in your stack? I dropped it off of mine cuz they said all things regarding methylation were false.
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Eye lightening I would guess.
I've taken 12g MSM for about 6 month. I had many other supps and a very healthy diet and veal liver alongside it. I had no side effects from MSM at all.
 
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Splinter901 said:
what would the purpose of msm be in your stack? I dropped it off of mine cuz they said all things regarding methylation were false.
Click to expand...
I just read your heightmaxxing thread from your experience can I gain 2 inches of height in 3-4 months if take mk677+cjc1295+huperzine A which togethor gives you 10iu per day combined with stretching and posture excercise ?
I'm 18
 
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ThousandCuts said:
Eye lightening I would guess.
I've taken 12g MSM for about 6 month. I had many other supps and a very healthy diet and veal liver alongside it. I had no side effects from MSM at all.
Click to expand...
did ur eyes actually get lighter
 
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I just feel side effects from taking 1000mg vitamin c/not drinking enough water. I'm staying at the 4g dosage because I am actually getting positive effects
 
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Splinter901 said:
what would the purpose of msm be in your stack? I dropped it off of mine cuz they said all things regarding methylation were false.
Click to expand...
"MSM was not toxic to osteoblastic cells and MSCs. MSM increased the expression of GH-related proteins including IGF-1R, p-IGF-1R, STAT5b, p-STAT5b, and Jak2 in osteoblastic cells and MSCs. MSM increased IGF-1R and GHR mRNA expression in osteoblastic cells."


www.ncbi.nlm.nih.gov

MSM Enhances GH Signaling via the Jak2/STAT5b Pathway in Osteoblast-Like Cells and Osteoblast Differentiation through the Activation of STAT5b in MSCs

Methylsulfonylmethane (MSM) is a naturally occurring sulfur compound with well-known anti-oxidant properties and anti-inflammatory activities. But, its effects on bone are unknown. Growth hormone (GH) is regulator of bone growth and bone metabolism. GH ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov

MSM enhances GH signaling via the Jak2/STAT5b pathway in osteoblast-like cells and osteoblast differentiation through the activation of STAT5b in MSCs - PubMed

Methylsulfonylmethane (MSM) is a naturally occurring sulfur compound with well-known anti-oxidant properties and anti-inflammatory activities. But, its effects on bone are unknown. Growth hormone (GH) is regulator of bone growth and bone metabolism. GH activates several signaling pathways such...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
 
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HimmyButler said:
With MSM, especially if you megadose it. It can cause bad side effects if your diet and other supplementation doesent support it. Basically, if depletes lots of the metals in our body, so you need to supplement choline (eggs), selenium, molbydenum, zinc, and copper. MSM can decrease their levels and possibly fuck you up. You should also supplement niacin because msm results in a build up of methyl groups and niacin helps clear them. VIt c as well and you needs magnesium glycine cause its a precursor in the lightening reactions for msm. Changes in the levels of anything will screw you up. Ive been on msm 4g+ for a six weeks now and now bad side effects at all, only lightening, Would not reccomend eating like 10g tho thats crazy. Anyone had any side effects?
Click to expand...
What kind of lightening
 
i take 2 3000mg msm pills a day no side effects
 
MEGA CHAD said:
I took 10g daily for 4 months and I didn't feel any type of side effects, I must stress that I also took vitamin d3+k2, vitamin C, NAC, I also took compounds for Heightmaxxing.

In a few months I will return to MSM megadose together with GH and IGF1 Lr3
Click to expand...
Any benefits
 
MEGA CHAD said:
"MSM was not toxic to osteoblastic cells and MSCs. MSM increased the expression of GH-related proteins including IGF-1R, p-IGF-1R, STAT5b, p-STAT5b, and Jak2 in osteoblastic cells and MSCs. MSM increased IGF-1R and GHR mRNA expression in osteoblastic cells."


www.ncbi.nlm.nih.gov

MSM Enhances GH Signaling via the Jak2/STAT5b Pathway in Osteoblast-Like Cells and Osteoblast Differentiation through the Activation of STAT5b in MSCs

Methylsulfonylmethane (MSM) is a naturally occurring sulfur compound with well-known anti-oxidant properties and anti-inflammatory activities. But, its effects on bone are unknown. Growth hormone (GH) is regulator of bone growth and bone metabolism. GH ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov

MSM enhances GH signaling via the Jak2/STAT5b pathway in osteoblast-like cells and osteoblast differentiation through the activation of STAT5b in MSCs - PubMed

Methylsulfonylmethane (MSM) is a naturally occurring sulfur compound with well-known anti-oxidant properties and anti-inflammatory activities. But, its effects on bone are unknown. Growth hormone (GH) is regulator of bone growth and bone metabolism. GH activates several signaling pathways such...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
Click to expand...
I believe it’s mostly safe but I saw some things about anxiety attacks and other ad side effects on Reddit
 
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HimmyButler said:
With MSM, especially if you megadose it. It can cause bad side effects if your diet and other supplementation doesent support it. Basically, if depletes lots of the metals in our body, so you need to supplement choline (eggs), selenium, molbydenum, zinc, and copper. MSM can decrease their levels and possibly fuck you up. You should also supplement niacin because msm results in a build up of methyl groups and niacin helps clear them. VIt c as well and you needs magnesium glycine cause its a precursor in the lightening reactions for msm. Changes in the levels of anything will screw you up. Ive been on msm 4g+ for a six weeks now and now bad side effects at all, only lightening, Would not reccomend eating like 10g tho thats crazy. Anyone had any side effects?
Click to expand...
Did ur skin lighten yet??
 
nice does it also take any heavy metals like mercury, lead, cadmium, nickel? if yes it's pretty god tier

on 2x2g a day for 2 weeks now. guess I'll eat more liver and eggs then :feelshmm:
 
Chinacurry said:
Did ur skin lighten yet??
Click to expand...
Hevent been able to use msm while on break from uni, but people have told me I look lighter even though I am just using nac and vit c. I will be able to use my full stack for a 2months next week and be able to come up with more defenitive co nclusions
\
 
a study i read said there were no side effects of msm even in doses of 30,000mg a day.
 
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trey123 said:
a study i read said there were no side effects of msm even in doses of 30,000mg a day.
Click to expand...
Its based on ancedotal shit people said of reddit




Better to be safe
 
I've taken 4g with NAC, and 1g of vitamin C for 4 months and I've seen results. It pretty much gives me glowing skin and even somewhat changed my hair texture/color. I would say it's worth trying.
 
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Nomad said:
I've taken 4g with NAC, and 1g of vitamin C for 4 months and I've seen results. It pretty much gives me glowing skin and even somewhat changed my hair texture/color. I would say it's worth trying.
Click to expand...
How much msm you took? Did it lighten skin
 
BrahminBoss said:
How much msm you took? Did it lighten skin
Click to expand...
4 grams daily, and yeah my skin did noticeably lighten. I also started wearing 50 spf sunscreen so that probably had an effect too.
 
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Nomad said:
4 grams daily, and yeah my skin did noticeably lighten. I also started wearing 50 spf sunscreen so that probably had an effect too.
Click to expand...
Link to brand?
 
Nomad said:
Nope, is it something I should look into? What does it do?
Click to expand...
Red undertones like this
FAD103DA C484 4E99 8E82 D50A00AF050D
 
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BUT... MUH... MUH LIGHTER EYE COLOUR
 
5.5psl said:
I just read your heightmaxxing thread from your experience can I gain 2 inches of height in 3-4 months if take mk677+cjc1295+huperzine A which togethor gives you 10iu per day combined with stretching and posture excercise ?
I'm 18
Click to expand...
Yeah i myself am laughing seeing this post of mine as of now lmfaoo
@smoothsexy
 
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smoothsexy said:
yes
Click to expand...
I haven't started doing it yet i am currently blasting 500 mg test and focus is to build muscle when i cruise i will try it and will make a post on it
 
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