My first 2000$/vial injection with CGRP inhibitors (Vyepti)

[Deleted member 153834]

had my first IV infusion yesterday, it was very fast-acting and in the evening i could feel my senses and everything getting much clearer.

background: ive been having debilitating migraine attacks, sometimes up to 5-6 times per week with very strong brainstem aura that included loss of vision, numbness in the left part of my body etc.

now that ive been awake for a couple of hours, it feels like ive been given access to consciousness premium:
-4k vision without loss of FOV,weird tracers,blurring
-clear thoughts, thinking hard is painless and i can focus hard without it triggering migraines
-NO FUCKING PAIN

niggers, this is awesome. i hope the effects will last, but they should supposedly get stronger after the first 3 months of treatment.

also: i pay 0$/month its all covered by insurance

@Dr. Mog @Hernan @Jason Voorhees

 

[Deleted member 153834]

idk if anybody else on here suffers from migraines but this medication has been really life-changing so far

 

[Jason Voorhees]

Happy for you, man. I don’t know much about infusions or migraines, my knowledge on these topics is very poor
but from what I understand you were in a lot of pain and now you’re not so that is good. Also I read the last line that it's covered by insurance so that's sweet aswell

 

[Deleted member 153834]

Happy for you, man. I don’t know much about infusions or migraines, my knowledge on these topics is very poor
but from what I understand you were in a lot of pain and now you’re not so that is good. Also I read the last line that it's covered by insurance so that's sweet aswell

yeah dude, i was sometimes out almost continuously for 3 months

 

[Ogionth]

idk if anybody else on here suffers from migraines but this medication has been really life-changing so far

Yeah, it's pretty documented.


What was your dosage btw?

 

[Deleted member 153834]

Yeah, it's pretty documented.


What was your dosage btw?

it was my first vial so i think i got 100mg. are you on them as well?

 

[Ogionth]

it was my first vial so i think i got 100mg. are you on them as well?

Nah, I'm not on them but I know about them

The placebo for them is very strong as well, in studies like if there's an 8 migraine decrease per month then around 5 are placebo but the treatment is statistically significant

 

[Deleted member 153834]

Nah, I'm not on them but I know about them

The placebo for them is very strong as well, in studies like if there's an 8 migraine decrease per month then around 5 are placebo but the treatment is statistically significant

yeah theyre great. also in the czech republic you dont have to beg your insurance to put you on anything, i was literally given a choice to pick ANY cgrp inhibtor option including oral (gepants) or auto-injections (ajovy etc). our healthcare is awesome

 

[mewzilla]

had my first IV infusion yesterday, it was very fast-acting and in the evening i could feel my senses and everything getting much clearer.

background: ive been having debilitating migraine attacks, sometimes up to 5-6 times per week with very strong brainstem aura that included loss of vision, numbness in the left part of my body etc.

now that ive been awake for a couple of hours, it feels like ive been given access to consciousness premium:
-4k vision without loss of FOV,weird tracers,blurring
-clear thoughts, thinking hard is painless and i can focus hard without it triggering migraines
-NO FUCKING PAIN

niggers, this is awesome. i hope the effects will last, but they should supposedly get stronger after the first 3 months of treatment.

also: i pay 0$/month its all covered by insurance

@Dr. Mog @Hernan @Jason Voorhees

heh he said aura

 

[Deleted member 153834]

heh he said aura

yeah bro migraine aura is just like in the animes its so awesome and cool

 

[Ogionth]

yeah theyre great. also in the czech republic you dont have to beg your insurance to put you on anything, i was literally given a choice to pick ANY cgrp inhibtor option including oral (gepants) or auto-injections (ajovy etc). our healthcare is awesome

I mean if they're willing to do CGRP inhib, then that's already amazing! They're extremely expensive once you account it annually.

Great man!

 

[Deleted member 153834]

I mean if they're willing to do CGRP inhib, then that's already amazing! They're extremely expensive once you account it annually.

Great man!

yeah theyre expensive as shit, but theyre fully covered after youve tried 2 types of prophylaxes, i did valproate and metoprolol, neither of which had any significant effect. so i was referred into a specialized center where they put me on vyepti after letting me pick

 

[avenox]

had my first IV infusion yesterday, it was very fast-acting and in the evening i could feel my senses and everything getting much clearer.

background: ive been having debilitating migraine attacks, sometimes up to 5-6 times per week with very strong brainstem aura that included loss of vision, numbness in the left part of my body etc.

now that ive been awake for a couple of hours, it feels like ive been given access to consciousness premium:
-4k vision without loss of FOV,weird tracers,blurring
-clear thoughts, thinking hard is painless and i can focus hard without it triggering migraines
-NO FUCKING PAIN

niggers, this is awesome. i hope the effects will last, but they should supposedly get stronger after the first 3 months of treatment.

also: i pay 0$/month its all covered by insurance

@Dr. Mog @Hernan @Jason Voorhees

Is this just for migrained or is this like a looksmaxxing thingy

 

[Ogionth]

yeah theyre expensive as shit, but theyre fully covered after youve tried 2 types of prophylaxes, i did valproate and metoprolol, neither of which had any significant effect. so i was referred into a specialized center where they put me on vyepti after letting me pick

I see.

Since when have you been having migraines?

Did you experience any weight gain from the appetite increase on Valproate btw?

 

[Deleted member 153834]

Is this just for migrained or is this like a looksmaxxing thingy

you cant really looksmaxx if youre lying in a dark/sound-proofed room all day ig lol. but only indirectly

 

[Deleted member 153834]

I see.

Since when have you been having migraines?

Did you experience any weight gain from the appetite increase on Valproate btw?

ive been havin migraines since i had meningitis at 14, typically every 6 months. but it intensified a lot during/after my trip to japan in 2023, when i was freshly 20. i was on valproate for only 2 months and i didnt get any of those sides.

 

[Ogionth]

ive been havin migraines since i had meningitis at 14, typically every 6 months. but it intensified a lot during/after my trip to japan in 2023, when i was freshly 20.

I see, I've never had a migraine myself but from people telling me it's an extremely bad experience

i was on valproate for only 2 months and i didnt get any of those sides.

 

[Deleted member 153834]

I see, I've never had a migraine myself but from people telling me it's an extremely bad experience

yeah, especially the hemiplegic/severe aura migraines are fucking horrible. you basically get a mini-stroke every fucking day, without permanent damage tho thankfully

 

[Ogionth]

yeah, especially the hemiplegic/severe aura migraines are fucking horrible. you basically get a mini-stroke every fucking day, without permanent damage tho thankfully

Sounds terrible, well it gets better man and it will, now that you're on CGRP inhib,

Hope it goes well for you! Have a good day!

 

[Dr. Mog]

It’s a legit treatment if you are willing to spend around 8k a year. These aren’t as common as you might think. Definitely a first world A tier city treatment lol.

Migraine in simple terms is just constriction of arteries in your brain, less blood supply = less oxygen = hypoxia of neural tissues leading to pain.

I would have suggested anti hypertensives like propranolol since they basically dilate and relax the arteries, if that isn’t strong enough only then move on to calcitonin gene related peptides.

Every time you came back from the hospital make sure to tell em to check for your BP too. Chronic infusion tends to, not all but sometimes, lead to hypertension especially if you have a genes for it - usually when parents too are hypertensive.

Also if you feel any extremities of your body, like toes and fingers turn a little cold or blue, look up Raynaud’s phenomenon, asses the similarity and then consult the doc ASAP.

 

[Deleted member 153834]

It’s a legit treatment if you are willing to spend around 8k a year. These aren’t as common as you might think. Definitely a first world A tier city treatment lol.

Migraine in simple terms is just constriction of arteries in your brain, less blood supply = less oxygen = hypoxia of neural tissues leading to pain.

I would have suggested anti hypertensives like propranolol since they basically dilate and relax the arteries, if that isn’t strong enough only then move on to calcitonin gene related peptides.

Every time you came back from the hospital make sure to tell em to check for your BP too. Chronic infusion tends to, not all but sometimes, lead to hypertension especially if you have a genes for it - usually when parents too are hypertensive.

Also if you feel any extremities of your body, like toes and fingers turn a little cold or blue, look up Raynaud’s phenomenon, asses the similarity and then consult the doc ASAP.

read the thread dude, i pay 0$ for it. in the czech republic its fully covered by insurance for everyone (you can pick which cgrp inhib you want as a patient, theyll give you anything for free). also i wrote that i took valproate and metoprolol before this to meet the insurance criteria. i only get the IV every 3 months, its very chill.

 

[Dr. Mog]

read the thread dude, i pay 0$ for it. in the czech republic its fully covered by insurance for everyone (you can pick which cgrp inhib you want as a patient, theyll give you anything for free). also i wrote that i took valproate and metoprolol before this to meet the insurance criteria. i only get the IV every 3 months, its very chill.

Shieeet mb I was too busy to read the thread. Happy for you tho.

Mirin the country’s health insurance scheme I just hope (((they))) aren’t infusing you with something else along with CGRPs