New Compound For Fat Cells In Face (GTFIH)

lacobus

lacobus

Up in the clouds, far from the crowds.
Joined
Aug 18, 2026
Posts
1,337
Reputation
1,574
I came across a cosmetic peptide called Acetyl Hexapeptide-38 (aka Adifyline).

Unlike most “anti-aging” peptides, it’s claimed to raise PGC-1α expression, a coactivator that works with PPARγ in fat cell development. The manufacturer’s own write up says it acts by “stimulating adipogenesis and leading to lipid storage and volume increase.”


A cream containing 2% Adifyline solution was tested on the fine asses 👅 of 22 women aged 50–60.


“After 14 days, areas treated with the cream containing acetyl hexapeptide-38 had a significant volume growth of 11.9% versus initial time, and 79% of volunteers experienced a visible volume enhancement.”


A summary of the brochure claims about a 12% increase in cheek volume.


Researchers tested Acetyl Hexapeptide-38 on human subcutaneous preadipocytes.


At 0.1 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 25.6%.”


At 0.5 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 61.1%.”


The measurement was PGC-1α expression. More importantly, they also measured actual lipid accumulation in the resulting adipocytes.


At 0.1 mg/mL:


“Enhanced lipid accumulation by 27.9%.”


At 0.5 mg/mL:


“Enhanced lipid accumulation by 32.4%.”


So what does this mean my niggas?

⬇️

Increases fat storage in the cells it’s applied to. The peptide raised PGC-1α in fat cell precursors, and those cells went on to store about 28–32% more lipid. Gaunt cells won’t have to suffer anymore.


IMG 5618
 
  • +1
  • Hmm...
  • JFL
Reactions: lowinhibragecel, ICR, Gen1leman and 9 others
Thats just sad to see no reply
 
  • +1
Reactions: lowinhibragecel, ICR, Gen1leman and 4 others
I came across a cosmetic peptide called Acetyl Hexapeptide-38 (aka Adifyline).

Unlike most “anti-aging” peptides, it’s claimed to raise PGC-1α expression, a coactivator that works with PPARγ in fat cell development. The manufacturer’s own write up says it acts by “stimulating adipogenesis and leading to lipid storage and volume increase.”


A cream containing 2% Adifyline solution was tested on the fine asses 👅 of 22 women aged 50–60.


“After 14 days, areas treated with the cream containing acetyl hexapeptide-38 had a significant volume growth of 11.9% versus initial time, and 79% of volunteers experienced a visible volume enhancement.”


A summary of the brochure claims about a 12% increase in cheek volume.


Researchers tested Acetyl Hexapeptide-38 on human subcutaneous preadipocytes.


At 0.1 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 25.6%.”


At 0.5 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 61.1%.”


The measurement was PGC-1α expression. More importantly, they also measured actual lipid accumulation in the resulting adipocytes.


At 0.1 mg/mL:


“Enhanced lipid accumulation by 27.9%.”


At 0.5 mg/mL:


“Enhanced lipid accumulation by 32.4%.”


So what does this mean my niggas?

⬇️

Increases fat storage in the cells it’s applied to. The peptide raised PGC-1α in fat cell precursors, and those cells went on to store about 28–32% more lipid. Gaunt cells won’t have to suffer anymore.


View attachment 5747721
Mirin the IQ and effort.
 
  • +1
Reactions: lowinhibragecel, ICR, Gen1leman and 2 others
  • +1
Reactions: lowinhibragecel, ICR, Gen1leman and 2 others
@Frenchshortcel123 bump thus
 
  • +1
Reactions: lowinhibragecel, ICR, Gen1leman and 3 others
I came across a cosmetic peptide called Acetyl Hexapeptide-38 (aka Adifyline).

Unlike most “anti-aging” peptides, it’s claimed to raise PGC-1α expression, a coactivator that works with PPARγ in fat cell development. The manufacturer’s own write up says it acts by “stimulating adipogenesis and leading to lipid storage and volume increase.”


A cream containing 2% Adifyline solution was tested on the fine asses 👅 of 22 women aged 50–60.


“After 14 days, areas treated with the cream containing acetyl hexapeptide-38 had a significant volume growth of 11.9% versus initial time, and 79% of volunteers experienced a visible volume enhancement.”


A summary of the brochure claims about a 12% increase in cheek volume.


Researchers tested Acetyl Hexapeptide-38 on human subcutaneous preadipocytes.


At 0.1 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 25.6%.”


At 0.5 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 61.1%.”


The measurement was PGC-1α expression. More importantly, they also measured actual lipid accumulation in the resulting adipocytes.


At 0.1 mg/mL:


“Enhanced lipid accumulation by 27.9%.”


At 0.5 mg/mL:


“Enhanced lipid accumulation by 32.4%.”


So what does this mean my niggas?

⬇️

Increases fat storage in the cells it’s applied to. The peptide raised PGC-1α in fat cell precursors, and those cells went on to store about 28–32% more lipid. Gaunt cells won’t have to suffer anymore.


View attachment 5747721
mirin thread
 
  • +1
Reactions: ICR, Gen1leman, Jordan Barrett and 3 others
high iq thread
 
  • +1
Reactions: lowinhibragecel, ICR, Gen1leman and 3 others
  • +1
  • Love it
Reactions: lowinhibragecel, ICR, Gen1leman and 2 others
  • +1
Reactions: Tayvion Cole, ICR, Gen1leman and 1 other person
I came across a cosmetic peptide called Acetyl Hexapeptide-38 (aka Adifyline).

Unlike most “anti-aging” peptides, it’s claimed to raise PGC-1α expression, a coactivator that works with PPARγ in fat cell development. The manufacturer’s own write up says it acts by “stimulating adipogenesis and leading to lipid storage and volume increase.”


A cream containing 2% Adifyline solution was tested on the fine asses 👅 of 22 women aged 50–60.


“After 14 days, areas treated with the cream containing acetyl hexapeptide-38 had a significant volume growth of 11.9% versus initial time, and 79% of volunteers experienced a visible volume enhancement.”


A summary of the brochure claims about a 12% increase in cheek volume.


Researchers tested Acetyl Hexapeptide-38 on human subcutaneous preadipocytes.


At 0.1 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 25.6%.”


At 0.5 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 61.1%.”


The measurement was PGC-1α expression. More importantly, they also measured actual lipid accumulation in the resulting adipocytes.


At 0.1 mg/mL:


“Enhanced lipid accumulation by 27.9%.”


At 0.5 mg/mL:


“Enhanced lipid accumulation by 32.4%.”


So what does this mean my niggas?

⬇️

Increases fat storage in the cells it’s applied to. The peptide raised PGC-1α in fat cell precursors, and those cells went on to store about 28–32% more lipid. Gaunt cells won’t have to suffer anymore.


View attachment 5747721
very interesting, could it be used around our eye area? more fat storage would be great
 
  • +1
Reactions: lowinhibragecel, Tayvion Cole, ICR and 2 others
very interesting, could it be used around our eye area? more fat storage would be great
From what I have researched it gives more fat storage on anywhere with skin

So probably around your eye area because well… It’s skin.
 
  • +1
Reactions: lowinhibragecel, Tayvion Cole, ICR and 4 others
Thats just sad to see no reply
Shameful this young nigga Iacobus is trying to help y'all young yutes.

Bump for a bro, I guess!
I came across a cosmetic peptide called Acetyl Hexapeptide-38 (aka Adifyline).
I mean, cool and good research, but there are many peptides or other things that have potential niche side effects (like fat growth).

I just don’t know if investing in the product is actually worth it… Especially when it's a niche new compound. And this was just a single study done on a small group of women.

However good a thread, man. And I won't say cope because I haven't tried. Just saying the results have a high chance of being skewed.

I'm going to rot and go the surgery route if needed instead, though, sorry!
 
  • +1
  • Love it
Reactions: lowinhibragecel, Tayvion Cole, ICR and 3 others
Shameful this young nigga Iacobus is trying to help y'all young yutes.

Bump for a bro, I guess!

I mean, cool and good research, but there are many peptides or other things that have potential niche side effects (like fat growth).

I just don’t know if investing in the product is actually worth it… Especially when it's a niche new compound. And this was just a single study done on a small group of women.

However good a thread, man. And I won't say cope because I haven't tried. Just saying the results have a high chance of being skewed.

I'm going to rot and go the surgery route if needed instead, though, sorry!
Bumping a brother !!!
 
  • +1
Reactions: lowinhibragecel, Tayvion Cole, ICR and 3 others
Shameful this young nigga Iacobus is trying to help y'all young yutes.

Bump for a bro, I guess!

I mean, cool and good research, but there are many peptides or other things that have potential niche side effects (like fat growth).

I just don’t know if investing in the product is actually worth it… Especially when it's a niche new compound. And this was just a single study done on a small group of women.

However good a thread, man. And I won't say cope because I haven't tried. Just saying the results have a high chance of being skewed.

I'm going to rot and go the surgery route if needed instead, though, sorry!
Thanks bro!

Don’t know if I will invest either, if I see more things about it maybe.
 
  • +1
Reactions: lowinhibragecel, Tayvion Cole, ICR and 2 others
From what I have researched it gives more fat storage on anywhere with skin

So probably around your eye area because well… It’s skin.
do you think it would have a meaninful change? (not fat graphting level obv). besides infras i cant think of other reasons to use it
 
  • +1
Reactions: Tayvion Cole, ICR, Gen1leman and 1 other person
do you think it would have a meaninful change? (not fat graphting level obv). besides infras i cant think of other reasons to use it
Not plenty of studies done with it, but from my research it seems to be effective.

Give it a try what’s the worst that could happen.
 
  • +1
Reactions: Tayvion Cole, ICR, Gen1leman and 1 other person
Not plenty of studies done with it, but from my research it seems to be effective.

Give it a try what’s the worst that could happen.
What's the difference between this and volufiline
 
  • +1
Reactions: Tayvion Cole, ICR, Gen1leman and 1 other person
  • +1
Reactions: lowinhibragecel, Tayvion Cole, Gen1leman and 1 other person
I came across a cosmetic peptide called Acetyl Hexapeptide-38 (aka Adifyline).

Unlike most “anti-aging” peptides, it’s claimed to raise PGC-1α expression, a coactivator that works with PPARγ in fat cell development. The manufacturer’s own write up says it acts by “stimulating adipogenesis and leading to lipid storage and volume increase.”


A cream containing 2% Adifyline solution was tested on the fine asses 👅 of 22 women aged 50–60.


“After 14 days, areas treated with the cream containing acetyl hexapeptide-38 had a significant volume growth of 11.9% versus initial time, and 79% of volunteers experienced a visible volume enhancement.”


A summary of the brochure claims about a 12% increase in cheek volume.


Researchers tested Acetyl Hexapeptide-38 on human subcutaneous preadipocytes.


At 0.1 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 25.6%.”


At 0.5 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 61.1%.”


The measurement was PGC-1α expression. More importantly, they also measured actual lipid accumulation in the resulting adipocytes.


At 0.1 mg/mL:


“Enhanced lipid accumulation by 27.9%.”


At 0.5 mg/mL:


“Enhanced lipid accumulation by 32.4%.”


So what does this mean my niggas?

⬇️

Increases fat storage in the cells it’s applied to. The peptide raised PGC-1α in fat cell precursors, and those cells went on to store about 28–32% more lipid. Gaunt cells won’t have to suffer anymore.


View attachment 5747721
Really informative thx
 
  • +1
Reactions: lowinhibragecel, Tayvion Cole and ICR
Why niggers literally post every fucking shit in off topic???
 
  • +1
  • JFL
Reactions: lowinhibragecel, NonnobisDomine, Tayvion Cole and 1 other person
I came across a cosmetic peptide called Acetyl Hexapeptide-38 (aka Adifyline).

Unlike most “anti-aging” peptides, it’s claimed to raise PGC-1α expression, a coactivator that works with PPARγ in fat cell development. The manufacturer’s own write up says it acts by “stimulating adipogenesis and leading to lipid storage and volume increase.”


A cream containing 2% Adifyline solution was tested on the fine asses 👅 of 22 women aged 50–60.


“After 14 days, areas treated with the cream containing acetyl hexapeptide-38 had a significant volume growth of 11.9% versus initial time, and 79% of volunteers experienced a visible volume enhancement.”


A summary of the brochure claims about a 12% increase in cheek volume.


Researchers tested Acetyl Hexapeptide-38 on human subcutaneous preadipocytes.


At 0.1 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 25.6%.”


At 0.5 mg/mL:


“Preadipocytes treated with acetyl hexapeptide-38 increased their expression by 61.1%.”


The measurement was PGC-1α expression. More importantly, they also measured actual lipid accumulation in the resulting adipocytes.


At 0.1 mg/mL:


“Enhanced lipid accumulation by 27.9%.”


At 0.5 mg/mL:


“Enhanced lipid accumulation by 32.4%.”


So what does this mean my niggas?

⬇️

Increases fat storage in the cells it’s applied to. The peptide raised PGC-1α in fat cell precursors, and those cells went on to store about 28–32% more lipid. Gaunt cells won’t have to suffer anymore.


View attachment 5747721
Son just discovered it :hnghn:
But actually cool thread
 
  • +1
Reactions: lowinhibragecel, Tayvion Cole and lacobus
Hi saars instead of using buccal fat removal or leaning, you should use this expriemental chinese tech research chemical peptide that is not available anywhere on the planet and costs 800+ dollars and you will get scammed buying it
@NonnobisDomine nigga what you think
 
  • +1
Reactions: lowinhibragecel, NonnobisDomine and Tayvion Cole
Hi saars instead of using buccal fat removal or leaning, you should use this expriemental chinese tech research chemical peptide that is not available anywhere on the planet and costs 800+ dollars and you will get scammed buying it
@NonnobisDomine nigga what you think
wallahi I js wanna loss fst naturslly
 
nice high effort thread

too bad this is the opposite of what i need i have horrible fat distribution in the face i need to get rid of
 
  • +1
Reactions: lacobus
nice high effort thread

too bad this is the opposite of what i need i have horrible fat distribution in the face i need to get rid of
I think Ghk-Cu would work for that, no?
 

Similar threads

hexum.dnd
Replies
2
Views
23
Surfsup
Surfsup
lacobus
Replies
39
Views
146
negative
negative
nel9d
Replies
1
Views
28
JJound
JJound
sub3forfemcels
Replies
5
Views
58
pfl
pfl
Spieluhr
Replies
1
Views
10
truesub5--
truesub5--

Users who are viewing this thread

  • lacobus
  • truesub5--
Back
Top