New niche compound to mitigate Aramotase inhibitors negative effects on cognition

[DoNotResusciate]

What is it
10β,17β-dihydroxyestra-1,4-dien-3-one or DHED is a prodrug designed to become E2 in the brain by metabolizing and binding to your ER alpha receptors.

This image shows how DHED is inactive in estrogen receptors but it converts to 17b estradiol through SDR mediated conversion and then binds to ERa/b receptors locally in the brain

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders - PMC​

Many neurological and psychiatric maladies originate from the deprivation of the human brain from estrogens. However, current hormone therapies cannot be used safely to treat these conditions commonly associated with menopause because of detrimental ...

pmc.ncbi.nlm.nih.gov
How can this be used in gear cycles

This can be used in gear cycles that use an aramotase inhibitor to reduce the conversion of testostrone into E2, because of it causing Gynecomastia or infertility when the levels are high, as an ancillary.
When E2 is nuked, estrogen signaling in the brain drops, reducing synaptic plasticity, BDNF expression, cholinergic and dopaminergic activity, and
overallneuronal energy metabolism, which can contribute to brain fog, poorer memory, and impaired cognition

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders - PMC​

Many neurological and psychiatric maladies originate from the deprivation of the human brain from estrogens. However, current hormone therapies cannot be used safely to treat these conditions commonly associated with menopause because of detrimental ...

pmc.ncbi.nlm.nih.gov

You can use this in your cycle to cancel out the negative effects on cognition from an aramotase inhibitor which is caused by low E2 by supplying it selectively to the brain so that we dont have to deal with gyno or infertility

 

[DoNotResusciate]

b

 

[AgentAngularity]

Wrong section of the forum

 

[DoNotResusciate]

b

 

[vexd]

dnr
its been debunked iqlet
aromaste inhibitors dont affect cognition one bit

 

[DoNotResusciate]

Wrong section of the forum

its not rly looksmaxing tho

 

[daunas]

What is it
10β,17β-dihydroxyestra-1,4-dien-3-one or DHED is a prodrug designed to become E2 in the brain by metabolizing and binding to your ER alpha receptors.

This image shows how DHED is inactive in estrogen receptors but it converts to 17b estradiol through SDR mediated conversion and then binds to ERa/b receptors locally in the brain

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders - PMC​

Many neurological and psychiatric maladies originate from the deprivation of the human brain from estrogens. However, current hormone therapies cannot be used safely to treat these conditions commonly associated with menopause because of detrimental ...

pmc.ncbi.nlm.nih.gov
How can this be used in gear cycles

This can be used in gear cycles that use an aramotase inhibitor to reduce the conversion of testostrone into E2, because of it causing Gynecomastia or infertility when the levels are high, as an ancillary.
When E2 is nuked, estrogen signaling in the brain drops, reducing synaptic plasticity, BDNF expression, cholinergic and dopaminergic activity, and
overallneuronal energy metabolism, which can contribute to brain fog, poorer memory, and impaired cognition

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders - PMC​

Many neurological and psychiatric maladies originate from the deprivation of the human brain from estrogens. However, current hormone therapies cannot be used safely to treat these conditions commonly associated with menopause because of detrimental ...

pmc.ncbi.nlm.nih.gov

You can use this in your cycle to cancel out the negative effects on cognition from an aramotase inhibitor which is caused by low E2 by supplying it selectively to the brain so that we dont have to deal with gyno or infertility

source?

 

[DoNotResusciate]

source?

Look at the fucking thread nigga

 

[DoNotResusciate]

dnr
its been debunked iqlet
aromaste inhibitors dont affect cognition one bit

The effect of aromatase inhibition on the cognitive function of older patients with breast cancer - PubMed

Although patients undergoing AI treatment had few changes in neuropsychological performance compared with healthy controls over a 6-month period, regionally specific changes in cerebral metabolic activity were identified during this interval in the patient group. Additional longitudinal...

pubmed.ncbi.nlm.nih.gov

do some fucking reasearch grey

 

[vexd]

The effect of aromatase inhibition on the cognitive function of older patients with breast cancer - PubMed

Although patients undergoing AI treatment had few changes in neuropsychological performance compared with healthy controls over a 6-month period, regionally specific changes in cerebral metabolic activity were identified during this interval in the patient group. Additional longitudinal...

pubmed.ncbi.nlm.nih.gov

do some fucking reasearch grey

im a grey
but know more than u
pls delete ur account and ur life

 

[DoNotResusciate]

View attachment 5334560
im a grey
but know more than u
pls delete ur account and ur life

look at the fucking study dumbass
it was made with children (not adults)
only 28 of them
They didnt nuke the estrogen of these boys like bodybuilders do
ANd they didnt detect significant differences in the limited cogntition tests they were given

 

[vexd]

look at the fucking study dumbass
it was made with children (not adults)
only 28 of them
They didnt nuke the estrogen of these boys like bodybuilders do
ANd they didnt detect significant differences in the limited cogntition tests they were given

yea significant
do you know what nootropic stacks are
also teens are taking AIs for extending the growth plates who's giving shit about shitty bodybuildingcels
pls kys

 

[DoNotResusciate]

yea significant
do you know what nootropic stacks are
also teens are taking AIs for extending the growth plates who's giving shit about shitty bodybuildingcels
pls kys

This thread isnt made for teens taking AIs dumbass. It says gear cycles.

I am going to rape you your mom, siblings(if any), foid (unlikely to have), dad, and ill stuff your head in your moms pussy which is now stretched enough to fit your head cuz of my enormous dick and im gonna take your moms head and fit it in ur pussy so its a circle and kinda looks like an ourobros

 

[vexd]

This thread isnt made for teens taking AIs dumbass. It says gear cycles.

I am going to rape you your mom, siblings(if any), foid (unlikely to have), dad, and ill stuff your head in your moms pussy which is now stretched enough to fit your head cuz of my enormous dick and im gonna take your moms head and fit it in ur pussy so its a circle and kinda looks like an ourobros

dnr
if I ever saw u I would just make u suck ur own cock and snap u like a twig
also life is not worth living past 20

 

[DoNotResusciate]

also life is not worth living past 20

For you maybe. Cuz youll be an Ourobros

 

[sasha108]

What is it
10β,17β-dihydroxyestra-1,4-dien-3-one or DHED is a prodrug designed to become E2 in the brain by metabolizing and binding to your ER alpha receptors.

This image shows how DHED is inactive in estrogen receptors but it converts to 17b estradiol through SDR mediated conversion and then binds to ERa/b receptors locally in the brain

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders - PMC​

Many neurological and psychiatric maladies originate from the deprivation of the human brain from estrogens. However, current hormone therapies cannot be used safely to treat these conditions commonly associated with menopause because of detrimental ...

pmc.ncbi.nlm.nih.gov
How can this be used in gear cycles

This can be used in gear cycles that use an aramotase inhibitor to reduce the conversion of testostrone into E2, because of it causing Gynecomastia or infertility when the levels are high, as an ancillary.
When E2 is nuked, estrogen signaling in the brain drops, reducing synaptic plasticity, BDNF expression, cholinergic and dopaminergic activity, and
overallneuronal energy metabolism, which can contribute to brain fog, poorer memory, and impaired cognition

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders - PMC​

Many neurological and psychiatric maladies originate from the deprivation of the human brain from estrogens. However, current hormone therapies cannot be used safely to treat these conditions commonly associated with menopause because of detrimental ...

pmc.ncbi.nlm.nih.gov

You can use this in your cycle to cancel out the negative effects on cognition from an aramotase inhibitor which is caused by low E2 by supplying it selectively to the brain so that we dont have to deal with gyno or infertility

Mirin the effort, but its really wrong section,it will disappear into a pile of shit here

 

[Aox Ofwar]

13M 5'4 can I reach 6'?

 

[NoidFiggerJew67]

Dnr but mirin the big words. Free rep

 

[DoNotResusciate]

13M 5'4 can I reach 6'?

only if you do masai jumps

 

[Aox Ofwar]

only if you do masai jumps

What if closes growth plates?