PDRN (GUIDE) (ANTI-AGING) (GTFIH)

[Rigged]

What is PDRN?
PDRN is a treatment used alot by rich ppl, derived from salmon DNA. Its extremely good for ppl who care about anti aging

Benefits:
— Fixes wrinkle, scars, literally anything that u would like fixed

How to DIY it:

What you need:
— PDRN PEPTIDE
— 31G, 1/2inch Insulin syringe
— Saline to reconsitute
— Alcohol wipes

Steps:
— Mix PDRN powder with saline solution follow instructions (1 ml per 10 mg of PDRN)
— Inject stomach or thigh so wipe with alcohol
— Use syringe to pull the liquid
— Pinch skin inject subq
— 1x a week 4-6 weeks

Where u can buy
— https://www.peptidesciences.com/
— https://www.corepeptides.com/
— https://www.gangnamstyle-shop.com/

Cost:
— $40-$100 per vial 1-2 vials per setion
— If you want to do it with in clinic itll cost $500-$1500 per session

https://www.gangnamlaser.com
in gangnam
https://www.lsaestheticclinic.com
in singapore
https://www.sw1clinic.com
In singapore
https://www.erufucare.com/clinic/bright-clinic
In malaysia
https://www.erufucare.com/clinic/ozhean-clinic-bangsar
In malaysia

 

[Rigged]

Posted this and another in vip section will post this one tdy other one tmrw both anti aging

 

[Sprinkles]

just stick a Jew needle up your ass for better skin bro

 

[Rigged]

just stick a Jew needle up your ass for better skin bro

Ima put something up ur ass alright

 

[Sprinkles]

Ima put something up ur ass alright

 

[AySab]

bro just rewrote my thread

 

[lestoa]

Posted this and another in vip section will post this one tdy other one tmrw both anti aging

can you send a screenshot of the vip section i want to see how it looks like

 

[AySab]

Steps
— Inject stomach or thigh so wipe with alcohol

wtf???
dumbest shit ive ever read.
i thought u were smarter than this.

 

[lilxder2]

erm okay

 

[gigell]

All these things are expensive asf

 

[Rigged]

bro just rewrote my thread

Nuh uh u just explained that it exists and a diff method

 

[Rigged]

wtf???
dumbest shit ive ever read.
i thought u were smarter than this.

Hows it stupid, u can inject pdrn, its better but has higher risk

 

[Rigged]

All these things are expensive asf

U can afford this with a 9-5 and a few weeks of saving

 

[AySab]

Hows it stupid, u can inject pdrn, its better but has higher risk

every single picture you just showed uses pdrn serum injection via mesotherapy.
pdrn only works on the fibroblast cells it comes in contact with, which is why its used with microneedling and injection into the epidermis (for direct fibroblast cell contact).
this isn’t some sort of steroid or peptide where it needs slow release and needs to be injected in the bloodstream…

 

[gigell]

U can afford this with a 9-5 and a few weeks of saving

I’m getting 200 bucks for one week of work soon

I’m also gonna try to find other jobs

 

[gigell]

every single picture you just showed uses pdrn serum injection via mesotherapy.
pdrn only works on the fibroblast cells it comes in contact with, which is why its used with microneedling and injection into the epidermis (for direct fibroblast cell contact).
this isn’t some sort of steroid or peptide where it needs slow release and needs to be injected in the bloodstream…

So what alterntiaves can be injected

I would try this when I’m older when I’ll go to Asia or something

 

[Rigged]

every single picture you just showed uses pdrn serum injection via mesotherapy.
pdrn only works on the fibroblast cells it comes in contact with, which is why its used with microneedling and injection into the epidermis (for direct fibroblast cell contact).
this isn’t some sort of steroid or peptide where it needs slow release and needs to be injected in the bloodstream…

Ur wrong u pin PDRN to interact with TNF-α and IL-6 vs mesotherapy which interacts with COL1A1 and COL3A1 and VEGF vs TIMPs, it doesnt relly on fibroblast contact idk where u got that idea from

Heres pinning results they look identical or better, also when u pin it goes through interstitial fluids which gets to more tissues this is way better for ovr tissue repair and it also boosts it

@gigell

 

[Rigged]

can you send a screenshot of the vip section i want to see how it looks like

No im gatekeeping if u want to see u have to pay @Master $100

 

[mathis]

it doesnt relly on fibroblast contact

 

[Rigged]

Nigga what its true it has 4 different mechanisms unrelated to fibroblast

 

[mathis]

Nigga what its true it has 4 different mechanisms unrelated to fibroblast

PDRN's interaction with fibroblasts is the main reason ( its not close ) of why this compound is used. Keep spreading bs

 

[Rigged]

PDRN's interaction with fibroblasts is the main reason ( its not close ) of why this compound is used. Keep spreading bs

literal ragebait from a guy who knows nothing

Frontiers | Pharmacological Activity and Clinical Use of PDRN

PDRN is a proprietary and registered drug that possesses several activities: tissue repairing, anti-ischemic, and anti-inflammatory. These therapeutic proper...

www.frontiersin.org

Polydeoxyribonucleotide: A Promising Biological Platform to Accelerate Impaired Skin Wound Healing

The normal wound healing process is characterized by a complex, highly integrated cascade of events, requiring the interactions of many cell types, including inflammatory cells, fibroblasts, keratinocytes and endothelial cells, as well as the involvement of growth factors and enzymes. However...

www.mdpi.com

Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes - Journal of Cell Communication and Signaling

This article summarizes important molecular mechanisms that drive aging in human skin from the perspective of dermal fibroblasts. The dermis comprises the bulk of the skin and is largely composed of a collagen‐rich extracellular matrix (ECM). The dermal ECM provides mechanical strength...

link.springer.com

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Wound healing is a physiological restorative response to tissue and cell injury. This process occurs in collaboration with a complex cascade of cellular events, including biochemical alterations to the extracellular matrix. Polydeoxyribonucleotide (PDRN) is a fragmented DNA mixture from...

www.spandidos-publications.com

 

[mathis]

literal ragebait from a guy who knows nothing

Frontiers | Pharmacological Activity and Clinical Use of PDRN

PDRN is a proprietary and registered drug that possesses several activities: tissue repairing, anti-ischemic, and anti-inflammatory. These therapeutic proper...

www.frontiersin.org

Polydeoxyribonucleotide: A Promising Biological Platform to Accelerate Impaired Skin Wound Healing

The normal wound healing process is characterized by a complex, highly integrated cascade of events, requiring the interactions of many cell types, including inflammatory cells, fibroblasts, keratinocytes and endothelial cells, as well as the involvement of growth factors and enzymes. However...

www.mdpi.com

Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes - Journal of Cell Communication and Signaling

This article summarizes important molecular mechanisms that drive aging in human skin from the perspective of dermal fibroblasts. The dermis comprises the bulk of the skin and is largely composed of a collagen‐rich extracellular matrix (ECM). The dermal ECM provides mechanical strength...

link.springer.com

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Wound healing is a physiological restorative response to tissue and cell injury. This process occurs in collaboration with a complex cascade of cellular events, including biochemical alterations to the extracellular matrix. Polydeoxyribonucleotide (PDRN) is a fragmented DNA mixture from...

www.spandidos-publications.com

Wont even bother replying
Insane low iq everyone that know a thing abt this compound would laught at you

 

[Rigged]

Wont even bother replying
Insane low iq everyone that know a thing abt this compound would laught at you

low iq retards after saying “muh i could reply and explain why ur wrong but i wont”

 

[AySab]

Ur wrong u pin PDRN to interact with TNF-α and IL-6 vs mesotherapy which interacts with COL1A1 and COL3A1 and VEGF vs TIMPs, it doesnt relly on fibroblast contact idk where u got that idea from

Heres pinning results they look identical or better, also when u pin it goes through interstitial fluids which gets to more tissues this is way better for ovr tissue repair and it also boosts it

@gigell

again, those images are utilising skinboosters which are administrated by mesotherapy to the face…
the only time they injected I.M was due to diabetic patients who needed overall healing support either for joints, bone, wounds around the body etc.
also, YOU NEED TO HAVE A WOUND FOR IT WORK (if you want to get rid of wrinkles). so injecting whenever isn’t going to help with wrinkles; the studies always use a open wound to study its effect or they directly inject into the skin graft.

 

[Rigged]

again, those images are utilising skinboosters which are administrated by mesotherapy to the face…
the only time they injected I.M was due to diabetic patients who needed overall healing support either for joints, bone, wounds around the body etc.
also, YOU NEED TO HAVE A WOUND FOR IT WORK (if you want to get rid of wrinkles). so injecting whenever isn’t going to help with wrinkles; the studies always use a open wound to study its effect or they directly inject into the skin graft.

@mathis both of yall are sum dumb niggas

PDRN ALSO works thru nucleotide salvage and A2A adenosine receptor activation, and also imagine making shit up studies show subq and IM injections EXTREMELY improve facial thru boosting collagen and cellular regen


Both these studies show wounds arent needed:

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Wound healing is a physiological restorative response to tissue and cell injury. This process occurs in collaboration with a complex cascade of cellular events, including biochemical alterations to the extracellular matrix. Polydeoxyribonucleotide (PDRN) is a fragmented DNA mixture from...

www.spandidos-publications.com

Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes - Journal of Cell Communication and Signaling

This article summarizes important molecular mechanisms that drive aging in human skin from the perspective of dermal fibroblasts. The dermis comprises the bulk of the skin and is largely composed of a collagen‐rich extracellular matrix (ECM). The dermal ECM provides mechanical strength...

link.springer.com

Id put u dumbasses both on ignore but then itd seem like im folding ill keep replying both u retards

 

[´´´´´´´´]

does it thicken the superficial musculoaponeurotic system?

 

[Rigged]

does it thicken the superficial musculoaponeurotic system?

No

 

[AySab]

@mathis both of yall are sum dumb niggas

PDRN ALSO works thru nucleotide salvage and A2A adenosine receptor activation, and also imagine making shit up studies show subq and IM injections EXTREMELY improve facial thru boosting collagen and cellular regen


Both these studies show wounds arent needed:

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Wound healing is a physiological restorative response to tissue and cell injury. This process occurs in collaboration with a complex cascade of cellular events, including biochemical alterations to the extracellular matrix. Polydeoxyribonucleotide (PDRN) is a fragmented DNA mixture from...

www.spandidos-publications.com

Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes - Journal of Cell Communication and Signaling

This article summarizes important molecular mechanisms that drive aging in human skin from the perspective of dermal fibroblasts. The dermis comprises the bulk of the skin and is largely composed of a collagen‐rich extracellular matrix (ECM). The dermal ECM provides mechanical strength...

link.springer.com

Id put u dumbasses both on ignore but then itd seem like im folding ill keep replying both u retards

no. you’re correct, although that doesn’t disprove my point which was in order to get the benefits on anti-aging (skin wise) you’ll still need to activate a natural healing response.
if you’re just targeting cells (around the whole body) that have been degraded due to aging, then injecting it in your body seems optimal.

 

[AySab]

@mathis both of yall are sum dumb niggas

PDRN ALSO works thru nucleotide salvage and A2A adenosine receptor activation, and also imagine making shit up studies show subq and IM injections EXTREMELY improve facial thru boosting collagen and cellular regen


Both these studies show wounds arent needed:

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Wound healing is a physiological restorative response to tissue and cell injury. This process occurs in collaboration with a complex cascade of cellular events, including biochemical alterations to the extracellular matrix. Polydeoxyribonucleotide (PDRN) is a fragmented DNA mixture from...

www.spandidos-publications.com

Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes - Journal of Cell Communication and Signaling

This article summarizes important molecular mechanisms that drive aging in human skin from the perspective of dermal fibroblasts. The dermis comprises the bulk of the skin and is largely composed of a collagen‐rich extracellular matrix (ECM). The dermal ECM provides mechanical strength...

link.springer.com

Id put u dumbasses both on ignore but then itd seem like im folding ill keep replying both u retards

also one of the studies don’t even mention PDRN use except if you’re proposing that PDRN intiates TGF-Beta activity.

 

[AySab]

@mathis both of yall are sum dumb niggas

PDRN ALSO works thru nucleotide salvage and A2A adenosine receptor activation, and also imagine making shit up studies show subq and IM injections EXTREMELY improve facial thru boosting collagen and cellular regen


Both these studies show wounds arent needed:

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Wound healing is a physiological restorative response to tissue and cell injury. This process occurs in collaboration with a complex cascade of cellular events, including biochemical alterations to the extracellular matrix. Polydeoxyribonucleotide (PDRN) is a fragmented DNA mixture from...

www.spandidos-publications.com

Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes - Journal of Cell Communication and Signaling

This article summarizes important molecular mechanisms that drive aging in human skin from the perspective of dermal fibroblasts. The dermis comprises the bulk of the skin and is largely composed of a collagen‐rich extracellular matrix (ECM). The dermal ECM provides mechanical strength...

link.springer.com

Id put u dumbasses both on ignore but then itd seem like im folding ill keep replying both u retards

not to mention, every single photo you’ve provided uses a pdrn serum which has been injected via mesotherapy to stimulate fibroblast cells to release growth factors and blah blah all that good stuff.
you’ve been providing studies that use PDRN as a compound, so yes, i am wrong as this is a different method of use.

 

[AySab]

So what alterntiaves can be injected

I would try this when I’m older when I’ll go to Asia or something

just inject hGH peptides honestly.
it’ll probably open more growth pathways due to IGF-1 stimulation.

 

[Rigged]

no. you’re correct, although that doesn’t disprove my point which was in order to get the benefits on anti-aging (skin wise) you’ll still need to activate a natural healing response.
if you’re just targeting cells (around the whole body) that have been degraded due to aging, then injecting it in your body seems optimal.

I js took lasix since im going to a party rn so i feel sick af and ill reply short
It does affect anti aging and skin either way without wounds

 

[AySab]

I js took lasix since im going to a party rn so i feel sick af and ill reply short
It does affect anti aging and skin either way without wounds

i took some furosemide too, on the train rn.

 

[Rigged]

also one of the studies don’t even mention PDRN use except if you’re proposing that PDRN intiates TGF-Beta activity.

Im not proposing it does upregulate TGF-Beta

 

[AySab]

Im not proposing it does upregulate TGF-Beta

then I understand, i’m wrong.

 

[Rigged]

not to mention, every single photo you’ve provided uses a pdrn serum which has been injected via mesotherapy to stimulate fibroblast cells to release growth factors and blah blah all that good stuff.
you’ve been providing studies that use PDRN as a compound, so yes, i am wrong as this is a different method of use.

The pics ive used all are pinning

 

[AySab]

Im not proposing it does upregulate TGF-Beta

never knew it had that function since I’ve only researched it uses with treating acne scarring.

 

[Rigged]

then I understand, i’m wrong.

nah ur a good ass user tbh

 

[AySab]

The pics ive used all are pinning

no, they use mesotherapy buddy.
it literally says skin boosters under the pictures and the laser clinic uses mesotherapy too.

 

[Rigged]

no, they use mesotherapy buddy.
it literally says skin boosters under the pictures and the laser clinic uses mesotherapy too.

Mb i was thinking of the other guide i posted similar to this, the 2nd pic does inject tho

 

[Rigged]

no, they use mesotherapy buddy.
it literally says skin boosters under the pictures and the laser clinic uses mesotherapy too.

Thread 'EXOSOME (GUIDE) (ANTI-AGING) (GTFIH)'
https://looksmax.org/threads/exosome-guide-anti-aging-gtfih.1078943/

Heres the other one

 

[AySab]

Mb i was thinking of the other guide i posted similar to this, the 2nd pic does inject tho

what was the other guide?

 

[mathis]

PDRN ALSO works thru nucleotide salvage and A2A adenosine receptor acactivation

Where do i say otherwise What an immature dumbass.
You’ll never be able to accept being wrong