H
Hemoscrit
Iron
- Joined
- Mar 4, 2024
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What proviron is
Proviron is a DHT derivative that carries an androgenic rating of 30-40 and an anabolic rating of 100-150. All ratings are measured against testosterone, which carries a rating of 100 in both categories.
The effects of Proviron
Although Proviron carries a higher than testosterone anabolic rating, very little anabolic effects are observed when taken because 3α-hydroxysteroid dehydrogenase (3α-HSD) disables Proviron inside skeletal muscular tissue, so you won't be making observable muscular gains with pure Proviron usage. Mesterolone(Proviron) has an extremely strong binding affinity to Sex-Hormone-Binding-Globulin (SHBG), By binding to SHBG mesterolone(Proviron) will increase the amount of circulating free testosterone. Proviron also has the ability to interact with aromatase, the enzyme that converts of testosterone to estrogen. By binding to the aromatase enzyme Proviron can mildly inhibit aromatase activity, thereby lowering estrogen. Please take into note It will not carry an anti-estrogenic effect near the level of power of an Aromatase Inhibitor (AI) but it will be notable and likely to have some impact in delaying growth plate ossification (Aromatase inhibitors in men: effects and therapeutic options - PMC (nih.gov)). The androgenic effects may play a role in helping masculinize your face during puberty (SNPs Associated With Testosterone Levels Influence Human Facial Morphology - PMC (nih.gov)).
DO NOT REPLACE AN AI WITH PROVIRON, but make sure to account for proviron dosage when taking an aromatase inhibitor to not destroy estrogen levels. Estrogen is neuroprotective, please do not completely eliminate it. Bloodwork is king on these topics.
Safety concerns -
There are concerns about Proviron negatively affect lipid profiles and inducing pathogenic cardiac hypertrophy(heart enlargement), but these effects can be treated by aerobic training(Adverse effect of the anabolic-androgenic steroid mesterolone on cardiac remodelling and lipoprotein profile is attenuated by aerobicz exercise training - PubMed (nih.gov)).
Hair loss and hair line receding as this is a DHT derived compound. You can attempt to attenuate this by using research chemical RU55841 which binds to androgen receptors on the hair and prevents Proviron from inducing hair loss.
Please Comment if you have any other safety concerns so I can address them for you.
Dosage
A dosage of 25-100mg/day has been shown to have minimal suppressive effect on the HPTA
Tldr - Proviron in puberty has a chance to masculinize you, can slightly reduce estrogen levels, and increase free testosterone levels in your body, has side effects of hurting lipid profile and inducing heart enlargement. Side effects reduced by aerobic exercise and hair loss medication.
Proviron is a DHT derivative that carries an androgenic rating of 30-40 and an anabolic rating of 100-150. All ratings are measured against testosterone, which carries a rating of 100 in both categories.
The effects of Proviron
Although Proviron carries a higher than testosterone anabolic rating, very little anabolic effects are observed when taken because 3α-hydroxysteroid dehydrogenase (3α-HSD) disables Proviron inside skeletal muscular tissue, so you won't be making observable muscular gains with pure Proviron usage. Mesterolone(Proviron) has an extremely strong binding affinity to Sex-Hormone-Binding-Globulin (SHBG), By binding to SHBG mesterolone(Proviron) will increase the amount of circulating free testosterone. Proviron also has the ability to interact with aromatase, the enzyme that converts of testosterone to estrogen. By binding to the aromatase enzyme Proviron can mildly inhibit aromatase activity, thereby lowering estrogen. Please take into note It will not carry an anti-estrogenic effect near the level of power of an Aromatase Inhibitor (AI) but it will be notable and likely to have some impact in delaying growth plate ossification (Aromatase inhibitors in men: effects and therapeutic options - PMC (nih.gov)). The androgenic effects may play a role in helping masculinize your face during puberty (SNPs Associated With Testosterone Levels Influence Human Facial Morphology - PMC (nih.gov)).
DO NOT REPLACE AN AI WITH PROVIRON, but make sure to account for proviron dosage when taking an aromatase inhibitor to not destroy estrogen levels. Estrogen is neuroprotective, please do not completely eliminate it. Bloodwork is king on these topics.
Safety concerns -
There are concerns about Proviron negatively affect lipid profiles and inducing pathogenic cardiac hypertrophy(heart enlargement), but these effects can be treated by aerobic training(Adverse effect of the anabolic-androgenic steroid mesterolone on cardiac remodelling and lipoprotein profile is attenuated by aerobicz exercise training - PubMed (nih.gov)).
Hair loss and hair line receding as this is a DHT derived compound. You can attempt to attenuate this by using research chemical RU55841 which binds to androgen receptors on the hair and prevents Proviron from inducing hair loss.
Please Comment if you have any other safety concerns so I can address them for you.
Dosage
A dosage of 25-100mg/day has been shown to have minimal suppressive effect on the HPTA
Tldr - Proviron in puberty has a chance to masculinize you, can slightly reduce estrogen levels, and increase free testosterone levels in your body, has side effects of hurting lipid profile and inducing heart enlargement. Side effects reduced by aerobic exercise and hair loss medication.
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