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Kraken
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“Side effects of rapamycin treatment are not limited to immunosuppression. Rapamycin treatment promotes insulin resistance, severe glucose intolerance, and increased gluconeogenesis by impairing lipid deposition in rat adipose tissue (Houde et al., 2010). Cataracts were increased and testicular degeneration was observed in 83% of rapamycin-treated male mice (Wilkinson et al., 2012). All stages of spermatogenesis were lost and the location where sperm should be was filled with multinucleate giant cells, dead cells from different stages, and debris. The full effects was apparent even in those mice receiving the lowest rapamycin dose (Wilkinson et al., 2012).“
I’ve seen some talk about topical rapamycin to address skin aging, which is an interesting idea.
I’ve seen some talk about topical rapamycin to address skin aging, which is an interesting idea.