Rating every drug I’ve tried (Oral, Injectable, Intranasal, Topical)

bruhtoobrutal

bruhtoobrutal

youthful twink
Joined
Jan 15, 2025
Posts
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S tier
Isotretinoin
DNP

A tier
Topical Minoxidil
Latisse (bimatoprost)
Retatrutide
Tirzepatide
Eplerenone
Furosemide
Testosterone
HGH
Alcohol

B tier
DSIP
High dose melatonin
Pregabalin
Baclofen
GB-115
TAK653
ACD856
Tadalafil

C tier
Tazarotene 0.1%
Injectable GHK-Cu
T3/T4
exemestane
Letrozole
Nicotine
BPC-157/TB-500

D tier
Hydroquinone
Metformin
Bromantane

F tier
Weed
Oral Minoxidil
 
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😗🤌
 
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holy avi mirin
 
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GB-115
TAK653
ACD856
new day new research chemical :ogre:

What do they do?
 
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What problems did you have with oral minox?
 
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GB-115
TAK653
ACD856
new day new research chemical :ogre:

What do they do?
ACD856- Enhances signaling of neurotrophins like NGF and BDNF

TAK653- enhances excitatory glutamate signaling. Activates ERk, mTor & AKT pathways. Increases BDNF

GB-115- combats anxiety by blocking CCK-1 receptors, Non sedative and no potential for abuse.

:feelsgood:
 
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ACD856- Enhances signaling of neurotrophins like NGF and BDNF

TAK653- enhances excitatory glutamate signaling. Activates ERk, mTor & AKT pathways. Increases BDNF

GB-115- combats anxiety by blocking CCK-1 receptors, Non sedative and no potential for abuse.

:feelsgood:
Have you tried any of them? If so how was your experience, and did you get any downsides?
 
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ACD856- Enhances signaling of neurotrophins like NGF and BDNF

TAK653- enhances excitatory glutamate signaling. Activates ERk, mTor & AKT pathways. Increases BDNF

GB-115- combats anxiety by blocking CCK-1 receptors, Non sedative and no potential for abuse.

:feelsgood:
Can you expand on each one, reasoning behind the placements?
 
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What problems did you have with oral minox?
Many

#1. Main reason it’s F tier is because of the insane bloating you get. Man even diuretics can’t help much.

#2. Grows hairs in unwanted areas

#3. Skin issues
 
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Have you tried any of them? If so how was your experience, and did you get any downsides?
Can you expand on each one, reasoning behind the placements?
TAK/ACD- combining these is a must, they make a good synergistic combo. My mood felt way better, I felt way clearer. Don’t expect anything crazy though + you gotta be consistent with it.

GB-115- Good, it works for Generalized anxiety. Don’t recommend for social anxiety though.
 
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TAK/ACD- combining these is a must, they make a good synergistic combo. My mood felt way better, I felt way clearer. Don’t expect anything crazy though + you gotta be consistent with it.

GB-115- Good, it works for Generalized anxiety. Don’t recommend for social anxiety though.
I mean for all of them, I assume based on ur title uve tried all of them?
 
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I mean for all of them, I assume based on ur title uve tried all of them?
not giving an explanation on all of them
pretty self explanatory just ask about certain ones if you want
 
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S tier
Isotretinoin
DNP

A tier
Topical Minoxidil
Latisse (bimatoprost)
Retatrutide
Tirzepatide
Eplerenone
Furosemide
Testosterone
HGH
Alcohol

B tier
DSIP
High dose melatonin
Pregabalin
Baclofen
GB-115
TAK653
ACD856
Tadalafil

C tier
Tazarotene 0.1%
Injectable GHK-Cu
T3/T4
exemestane
Letrozole
Nicotine
BPC-157/TB-500

D tier
Hydroquinone
Metformin
Bromantane

F tier
Weed
Oral Minoxidil
Why’s hydroquinone d tier?
 
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It’s more a dark spot remover and way too potent. People usually come out looking like albinos/ way too pale.
I’m using it as a skin lightening treatment after seeing all the skin bleaching threads
 
I’m using it as a skin lightening treatment after seeing all the skin bleaching threads
trust go with something softer like Kojic Acid or TXA acid

The end result will not satisfy you
It left my skin very unbalanced and way too pale, I recovered from it now but it was brutal for like 3 months.
 
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Why is dnp so high is it really alldat
Yes it is a fucking life changer
I can never look at weight loss the same after discovering DNP

Imagine this a pill that literally shreds through pounds that would otherwise take WEEKS of consistency. Get fat eat whatever you want, pop some DNP for the week, just chill in front of a fan butt naked and watch all that go away.
 
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Yes it is a fucking life changer
I can never look at weight loss the same after discovering DNP

Imagine this a pill that literally shreds through pounds that would otherwise take WEEKS of consistency. Get fat eat whatever you want, pop some DNP for the week, just chill in front of a fan butt naked and watch all that go away.
Wow, so you didn’t experience any significant lethargy or other sides while using it?
 
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Mirin the list.

I have dnp laying around for muh next cut. So excited :soy::soy:
 
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Yes it is a fucking life changer
I can never look at weight loss the same after discovering DNP

Imagine this a pill that literally shreds through pounds that would otherwise take WEEKS of consistency. Get fat eat whatever you want, pop some DNP for the week, just chill in front of a fan butt naked and watch all that go away.
What dose u using?
 
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Why weed at f its not that bad in my opinion
 
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Wow, so you didn’t experience any significant lethargy or other sides while using it?
Yeah I did

Dehydrated, Burning, Yellow cum, Felt lethargic 24/7, Scared to death going to sleep

But it’s all worth it ngl
I shred like 10 pounds in a week I forgot tbh

I’ve ran about 3 cycles now
 
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Mirin the list.

I have dnp laying around for muh next cut. So excited :soy::soy:
DNP mogs so hard
I needa restock before summer hits
I’ve ran DNP in summer it was literal hell
What dose u using?
I’ve always done 400mg, perfect dose.
I always run it along a GLP like reta or tirz and sometimes T3. I was loosing like a pound a day if I remember or more.
 
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TAK/ACD- combining these is a must, they make a good synergistic combo. My mood felt way better, I felt way clearer. Don’t expect anything crazy though + you gotta be consistent with it.
How is your thinking and perception compared to baseline?
How does it compound over time (the benefits)?
 
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Why weed at f its not that bad in my opinion
It overactives my amygdala way too much
Makes me too anxious and too lazy. Specially carts, those shits fried my brain ngl.
 
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Why D? Does it not work?
It does work, a little too good.
It’s too potent the finish isn’t desired
Left my skin very uneven like white patches, My family all pointed it out. Also it left me WAY TOO pale not lightened.
 
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It overactives my amygdala way too much
Makes me too anxious and too lazy. Specially carts, those shits fried my brain ngl.
Understandable and ive never had a cart only the actual green
 
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trust go with something softer like Kojic Acid or TXA acid

The end result will not satisfy you
It left my skin very unbalanced and way too pale, I recovered from it now but it was brutal for like 3 months.
I need it to fix some dark areas.
Are you sure Kojic and TXA are not cope?
 
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It does work, a little too good.
It’s too potent the finish isn’t desired
Left my skin very uneven like white patches, My family all pointed it out. Also it left me WAY TOO pale not lightened.
What if it's diluted and used over time? Do you still think it would work?
 
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I need it to fix some dark areas.
Are you sure Kojic and TXA are not cope?
If it’s some dark spots you can use hydroquinone. Kojic and TXA are not cope for full facial skin lightening, they just take longer to work, the finish is way more even, gentler and natural.
 
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What if it's diluted and used over time? Do you still think it would work?
It did work tbh
All my friends told me I got whiter, but like paleish. In the beginning hydroquinone raped my skin and left me looking like Michael Jackson.


I just wouldn’t touch it
Try softer options and if those don’t work after like a month move to stronger stuff.
 
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Understandable and ive never had a cart only the actual green
I still do it from time to time with my friends but I have to be in a very specific setting for it to enjoyable. Idk why in the beginning it made me low inhib asf then I just started getting extremely fucking anxious for some reason. Actual weed mogs carts hard though.
 
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I still do it from time to time with my friends but I have to be in a very specific setting for it to enjoyable. Idk why in the beginning it made me low inhib asf then I just started getting extremely fucking anxious for some reason. Actual weed mogs carts hard though.
You just gotta chill out lay down and take deep breaths then the anxiety goes away and youre chilled asf and hungry asf
 
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Commentary on this?
Nothing tbh
I bought this when I was just starting out, didn’t even know what it did. Seems very promising though, a lot of good anecdotal reviews seems most effective when injected locally into the injured site.
 
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You just gotta chill out lay down and take deep breaths then the anxiety goes away and youre chilled asf and hungry asf
That’s also another reason why I put it F tier

I was tapping that shit everyday in summer I gained 10 pounds. it made me way too hungry I was eating the entire kitchen. Indirect looksmin.
 
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That’s also another reason why I put it F tier

I was tapping that shit everyday in summer I gained 10 pounds. it made me way too hungry I was eating the entire kitchen. Indirect looksmin.
Brah limit it to once a week that shit fries your brain
 
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Why topical minox over oral
 
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Dnp and alcohol so high???
 
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Dnp and alcohol so high???
DNP is a God tier drug

Alcohol is a fun time
(I’m currently hung over asf from last night)
 
Yeah I did

Dehydrated, Burning, Yellow cum, Felt lethargic 24/7, Scared to death going to sleep

But it’s all worth it ngl
I shred like 10 pounds in a week I forgot tbh

I’ve ran about 3 cycles now
I forgot to ask yesterday, but how would you say the nutrient partitioning is? Did you experience much muscle loss?
 
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trust go with something softer like Kojic Acid or TXA acid

The end result will not satisfy you
It left my skin very unbalanced and way too pale, I recovered from it now but it was brutal for like 3 months.
The thing is I’m not sure kojic or TXA will work on my shitskin. Hence why I’m using hydro, but I’m also using vit c and taz with it to help with the undertones and evenness
 
I forgot to ask yesterday, but how would you say the nutrient partitioning is? Did you experience much muscle loss?
DNP is muscle sparing
 
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S tier
Isotretinoin
DNP

A tier
Topical Minoxidil
Latisse (bimatoprost)
Retatrutide
Tirzepatide
Eplerenone
Furosemide
Testosterone
HGH
Alcohol

B tier
DSIP
High dose melatonin
Pregabalin
Baclofen
GB-115
TAK653
ACD856
Tadalafil

C tier
Tazarotene 0.1%
Injectable GHK-Cu
T3/T4
exemestane
Letrozole
Nicotine
BPC-157/TB-500

D tier
Hydroquinone
Metformin
Bromantane

F tier
Weed
Oral Minoxidil
By "High dose melatonin" you mean how many ?
 
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