retinoid receptors and dht

[neo28]

retinoids work through RXR and RAR receptors that directly compete with androgen receptors which is why they work so well for acne, something that people don’t realize is that this exact same mechanism applies to hair loss as well, it’s mechanistically sound and there’s emerging research that backs this. stop nuking your natural hormonal balance with finasteride when you can use retinoids for the same benefits in a controlled manner without fighting your own physiology.

studies:

https://academic.oup.com/mend/article-abstract/19/5/1200/2737980?redirectedFrom=fulltext

https://www.mdpi.com/1422-0067/25/17/9245

The mechanistic insights into the application of retinoids... : Annals of Medicine and Surgery

ition and androgenic activity, especially dihydrotestosterone. The paradoxical role of androgens – promoting hair growth in some areas while suppressing it on the scalp – has been key in understanding AGA’s pathogenesis. Altered androgen receptor signaling in dermal papilla cells contributes...

journals.lww.com

https://onlinelibrary.wiley.com/doi/10.1111/jdv.20000

 

[81xa]

good to know
repped

 

[Sub->CL]

doubt

 

[mohito]

Hair loss is driven by androgen receptor activity, not retinoid receptor signaling

 

[andy9432]

so accutane can stop hair loss?