Second DNP Run (Need Experienced Users to Weigh In)

[Sayori]

Cycle length:
12 days

Dosing:
200 mg daily

Goal:
lose 10 pounds of fat min

What I expect from this thread:
Tag people you know who have used dnp
So, they can tell me about their experience after

My experience after my first dnp cycle:
I would get tired fast
example: walking upstairs would gas me

Life fuel:
all the post dnp sides are gone now I feel great

tags:
@orbitro @goku21 @Canthus
@Grievous and his pooks @Starborn


​

 

[Leo]

Cycle length:
12 days

Dosing:
200 mg daily

Goal:
lose 10 pounds of fat min

What I expect from this thread:
Tag people you know who have used dnp
So, they can tell me about their experience after

My experience after my first dnp cycle:
I would get tired fast
example: walking upstairs would gas me

Life fuel:
all the post dnp sides are gone now I feel great

tags:
@orbitro @goku21 @Canthus
@Grievous and his pooks @Starborn


​

bump

 

[overrated]

Cycle length:
12 days

Dosing:
200 mg daily

Goal:
lose 10 pounds of fat min

What I expect from this thread:
Tag people you know who have used dnp
So, they can tell me about their experience after

My experience after my first dnp cycle:
I would get tired fast
example: walking upstairs would gas me

Life fuel:
all the post dnp sides are gone now I feel great

tags:
@orbitro @goku21 @Canthus
@Grievous and his pooks @Starborn


​

Valid cycle

 

[Sayori]

Bump

let's get this thread lively

I think the title is ahh ill get ai to make a click bait title for me

 

[overrated]

Bump

let's get this thread lively

I think the title is ahh ill get ai to make a click bait title for me

 

[overrated]

Bump

 

[Sayori]

Bump

thankyou nga

If two more bumps dont work ill but again every 30 min

 

[Sayori]

bump

@@@@

 

[Sayori]

ONE MORE bump

waiting 30 min before next one

 

[goku21]

In my own experience 200mg is the best dose 400mg it’s good too. I’ve felt tired and lazy at the gym on dnp. Stims help alot but post gym you crash heavy.

 

[Starborn]

@Grievous and his pooks @Starborn


​

not necessary nigga

 

[Sayori]

not necessary nigga

miss read nga

 

[Starborn]

nga u dont need to hide it

BRO CAN A NIGGA NOT COMUNICATE WITHBPEPLE ON HERE

niggas always saying I’m gay cuz I tag this dude in threads

 

[devonhendryx999]

Bumperino

 

[Sayori]

BRO CAN A NIGGA NOT COMUNICATE WITHBPEPLE ON HERE

niggas always saying I’m gay cuz I tag this dude in threads

Don't worry its cute

I support you two

 

[Sayori]

bump

+

https://looksmax.org/threads/sick-kunt31-evisceration-thread-hate-this-larp-nga.1941388/

 

[Canthus]

Mirin bro. Also cal intake?

 

[goku21]

Mirin bro. Also cal intake?

He don’t track nothing. But 1500 is doable and better to cut cals then to walk steps in a cut especially on DNP

 

[davidlaidisme67]

Cycle length:
12 days

Dosing:
200 mg daily

Goal:
lose 10 pounds of fat min

What I expect from this thread:
Tag people you know who have used dnp
So, they can tell me about their experience after

My experience after my first dnp cycle:
I would get tired fast
example: walking upstairs would gas me

Life fuel:
all the post dnp sides are gone now I feel great

tags:
@orbitro @goku21 @Canthus
@Grievous and his pooks @Starborn


​

Miring this mogs my experience with dnp. I felt like a human furnace

 

[Sayori]

He don’t track nothing. But 1500 is doable and better to cut cals then to walk steps in a cut especially on DNP

kys fag

i did track just not to the tea like an autist nga like you

I intuitively tracked my cals

but my weight tracking was spot on you don't need autistic tracking for dnp

 

[Canthus]

Miring this mogs my experience with dnp. I felt like a human furnace

Intresting. I didn’t feel anything worth a shit. Even on 400. Idk how. Just very mild warmth on and off

 

[Sayori]

Intresting. I didn’t feel anything worth a shit. Even on 400. Idk how. Just very mild warmth on and off

you're lucky I felt a lil hot on 200

It would make me a lil schizo as it was my first cycle

 

[Canthus]

you're lucky I felt a lil hot on 200

It would make me a lil schizo as it was my first cycle

Yeah I was worried it was bunk
Waiting for the water to clear now this is my first day off. I look like shit

 

[Sayori]

Yeah I was worried it was bunk
Waiting for the water to clear now this is my first day off. I look like shit

brootal shit inform me if you get out of breath doing activies you usally wouldnt get tired or out of breath for

 

[Ergogenic]

Cycle length:
12 days

Dosing:
200 mg daily

Goal:
lose 10 pounds of fat min

What I expect from this thread:
Tag people you know who have used dnp
So, they can tell me about their experience after

My experience after my first dnp cycle:
I would get tired fast
example: walking upstairs would gas me

Life fuel:
all the post dnp sides are gone now I feel great

tags:
@orbitro @goku21 @Canthus
@Grievous and his pooks @Starborn


​

Yes, your goal to lose 10 pounds or 4.5359237 kilograms of pure fat with an energy deficit and 2,4-dinitrophenol may be achievable.

I have used 400 milligrams of 2,4-dinitrophenol per day for some days in the past, but I could not tolerate 400 milligrams for many days. I felt weak all the time. I would drink 4 or 5 litres of water through the day and still feel thirsty. I eventually stopped using 2,4-dinitrophenol and threw all the capsules in a bin because my hands and feet started to burn all the time, and the scleras (white parts of eye) of my eyes had a slight orange tint on the far sides.

2,4-dinitrophenol also has the worst smell and taste ever. I hated tasting and swallowing it. I was gagging from having the powder exit the capsule and go on my tongue. Just thinking about it makes me shiver.

I plan on using it again, but at a lower dose of 200 milligrams instead of 400 milligrams like I did in my past.

 

[Canthus]

Yes, your goal to lose 10 pounds or 4.5359237 kilograms of pure fat with an energy deficit and 2,4-dinitrophenol may be achievable.

I have used 400 milligrams of 2,4-dinitrophenol per day for some days in the past, but I could not tolerate 400 milligrams for many days. I felt weak all the time. I would drink 4 or 5 litres of water through the day and still feel thirsty. I eventually stopped using 2,4-dinitrophenol and threw all the capsules in a bin because my hands and feet started to burn all the time, and the scleras (white parts of eye) of my eyes had a slight orange tint on the far sides.

2,4-dinitrophenol also has the worst smell and taste ever. I hated tasting and swallowing it. I was gagging from having the powder exit the capsule and go on my tongue. Just thinking about it makes me shiver.

I plan on using it again, but at a lower dose of 200 milligrams instead of 400 milligrams like I did in my past.

 

[Sayori]

Yes, your goal to lose 10 pounds or 4.5359237 kilograms of pure fat with an energy deficit and 2,4-dinitrophenol may be achievable.

I have used 400 milligrams of 2,4-dinitrophenol per day for some days in the past, but I could not tolerate 400 milligrams for many days. I felt weak all the time. I would drink 4 or 5 litres of water through the day and still feel thirsty. I eventually stopped using 2,4-dinitrophenol and threw all the capsules in a bin because my hands and feet started to burn all the time, and the scleras (white parts of eye) of my eyes had a slight orange tint on the far sides.

2,4-dinitrophenol also has the worst smell and taste ever. I hated tasting and swallowing it. I was gagging from having the powder exit the capsule and go on my tongue. Just thinking about it makes me shiver.

I plan on using it again, but at a lower dose of 200 milligrams instead of 400 milligrams like I did in my past.

Thank you for the high effort respond

However, my equerry was about the post side effects like low stamina, sleepiness, or something I haven't experienced

 

[Ergogenic]

Thank you for the high effort respond

However, my equerry was about the post side effects like low stamina, sleepiness, or something I haven't experienced

There were no post side effects. There should not be any after you discontinue using 2,4-dinitrophenol, and it leaves your system after some days.

 

[Sayori]

There were no post side effects. There should not be any after you discontinue using 2,4-dinitrophenol, and it leaves your system after some days.

you are incorrect there is post side that users have talked about

like tiredness

The oxidative stress should be causing this

 

[Ergogenic]

you are incorrect there is post side that users have talked about

like tiredness

The oxidative stress should be causing this

I was talking about my own experience.

The post side effects were certainly there for me after day 1 of discontinuing using 2,4-dinitrophenol. I still felt tired and weak and thirsty. What I meant is that there were no and should not be any post side effects after a few days of not using it and having it eliminate from your system.

 

[7zyzz7]

200mg is not enough to lose 10 lbs to fat in 12 days. the most you can lose in 12 days running that dose would probably be 5-6 lbs at most if youre doing 1-2 hours of cardio. make sure to have an antihistamine on hand for allergic reaction and for sleep. benedryl works well, i like this brand. https://www.genexa.com/products/kids-diphenhydramine-allergy-liquid

 

[7zyzz7]

the way i like to do is it i take 100mg per 45 min walk i go on. so i can manage two 45 min walks that day ill do 200mg, the if i can do 3 walks that would be 300mg. this way it will motivate you to move your ass. ive done DNP at 750mg for 2 weeks, and the method i described above (the walking method) works even better than high dose DNP.

walking is key on DNP. its not even funny. if you were walking 4 hours a day i would say on 200mg for 12 day then you just might be able to lose 10 lbs

our ancestor used to walk all day. walking burns fat and is relatively easy to do unless you have ankle/knee problems or severely over weight. if you are unemployed or a student just walk all day on DNP you will get shredded

 

[Sayori]

200mg is not enough to lose 10 lbs to fat in 12 days. the most you can lose in 12 days running that dose would probably be 5-6 lbs at most if youre doing 1-2 hours of cardio. make sure to have an antihistamine on hand for allergic reaction and for sleep. benedryl works well, i like this brand. https://www.genexa.com/products/kids-diphenhydramine-allergy-liquid

I have already run this Cyle before and lost 10 pounds

Yes, the dosage below was 50 mg higher however I am pretty confident my metabolic rate is higher than this ngas

Most misunderstood drug to lose 1lbs PURE FAT a day - FULL GUIDE

Disclaimer - dont do any recreational drugs like cocaine or drink alcohol while using DNP. (Moderator) Anyone who has done 0 research on it will say this: Some retards: If you are not an idiot when running this compound, that isn't going to happen. Be sensible and you will get insane fat loss...

looksmax.org

 

[Sayori]

the way i like to do is it i take 100mg per 45 min walk i go on. so i can manage two 45 min walks that day ill do 200mg, the if i can do 3 walks that would be 300mg. this way it will motivate you to move your ass. ive done DNP at 750mg for 2 weeks, and the method i described above (the walking method) works even better than high dose DNP.

walking is key on DNP. its not even funny. if you were walking 4 hours a day i would say on 200mg for 12 day then you just might be able to lose 10 lbs

our ancestor used to walk all day. walking burns fat and is relatively easy to do unless you have ankle/knee problems or severely over weight. if you are unemployed or a student just walk all day on DNP you will get shredded

mirin your effort

but thats to much work

I'll just up the dose instead of walk

 

[7zyzz7]

mirin your effort

but thats to much work

I'll just up the dose instead of walk

ok that works too. think i lost like 20 lbs running 625mg for 3 weeks back in 2022. But the rebound on DNP is brutal. I made the original DNP thread on this forum back in 2022 but i dont take it myself anymore. Ive rebounded at least 50% of the weight back over the next 4-5 months after every DNP cycle ive done.

TBH DNP is great for very obese people but its not a sustainable method of staying lean. unless your goal is to get lean and then be ready to eat way less calories then you were 2 weeks ago and sustain that but thats just brootal.

DNP almost works too well, and if you are not adjusted to your new body weight you will overeat likely. This is why reta works so well beacuse its fixing the root cause of weightloss which is caloric intake. the other root cause is metabolism. so if you can find a way to increase your metabolism while also not eating like a fatass then you will be lean for life quite easily.

ray peat says coconut oil allowed him to go longer between meals by increasing his thyroid function. i made a thread earlier today.

https://looksmax.org/threads/coconut-oil-for-fat-loss-natural-retatrutide.1941137/#post-27063301

So something like taking thyroid supplement daily and eating more coconut oil will be more sustainable than DNP in the long run. Althrough DNP is very great for rapid fatloss if you need to get lean before a certain date.

 

[Sayori]

ok that works too. think i lost like 20 lbs running 625mg for 3 weeks back in 2022. But the rebound on DNP is brutal. I made the original DNP thread on this forum back in 2022 but i dont take it myself anymore. Ive rebounded at least 50% of the weight back over the next 4-5 months after every DNP cycle ive done.

TBH DNP is great for very obese people but its not a sustainable method of staying lean. unless your goal is to get lean and then be ready to eat way less calories then you were 2 weeks ago and sustain that but thats just brootal.

DNP almost works too well, and if you are not adjusted to your new body weight you will overeat likely. This is why reta works so well beacuse its fixing the root cause of weightloss which is caloric intake. the other root cause is metabolism. so if you can find a way to increase your metabolism while also not eating like a fatass then you will be lean for life quite easily.

ray peat says coconut oil allowed him to go longer between meals by increasing his thyroid function. i made a thread earlier today.

https://looksmax.org/threads/coconut-oil-for-fat-loss-natural-retatrutide.1941137/#post-27063301

So something like taking thyroid supplement daily and eating more coconut oil will be more sustainable than DNP in the long run. Althrough DNP is very great for rapid fatloss if you need to get lean before a certain date.

The thyroid effects of dnp is what makes the rebound brootal

however, its very minimal and easily negated

just take some reta and eat minimal calories and youll be good even after dnp

Also, that coconut thread is bullshit

 

[7zyzz7]

The thyroid effects of dnp is what makes the rebound brootal

yeah you can take a thyroid supplement while on DNP. i didnt use to take daily thyroid when i was running my DNP during those times. although one cycle i used 25mcg t3 daily with my DNP and that was the best DNP cycle i ever had. I think t4 is important too so t3/t4 combo is better for daily use. i take 1 grain daily of thyroid it hasnt made me lose weight but i can go longer in between meals without losing my mind i think t4 is very important also if you hypo and not just t3.

Also, that coconut thread is bullshit

nigga your nuts

 

[Sayori]

yeah you can take a thyroid supplement while on DNP. i didnt use to take daily thyroid when i was running my DNP during those times. although one cycle i used 25mcg t3 daily with my DNP and that was the best DNP cycle i ever had. I think t4 is important too so t3/t4 combo is better for daily use. i take 1 grain daily of thyroid it hasnt made me lose weight but i can go longer in between meals without losing my mind i think t4 is very important also if you hypo and not just t3.

nigga your nuts

I haven't ordered t3 yet

this dnp cycle will be ran without any supports other than post mot c and nad+ after the cycle

 

[7zyzz7]

I haven't ordered t3 yet

this dnp cycle will be ran without any supports other than post mot c and nad+ after the cycle

take low dose niacinamide multiple time throughout the day for NAD+

Vitamin B3 (Niacinamide) for Skin Health and Energy

Niacinamide supplements support skin health, boost cellular energy, and protect against toxins.

purebulk.com

i take 1/64th of tsp multiple times a day everyday

i would also recommend high vitamin C preferably from freshly squeezed orange juice and daily oyster or egg yolks for micronutrients.

T3 and T3/T4 combo product you can get from meds.com.mx/ cynoplus and cynomel

 

[7zyzz7]

yeah if were to run a DNP cycle today i would do:
Diet: orange juice, low fat chocolate milk, oysters, soda, egg yolks (in a protein shake w/ milk & cacao powder + sugar/dextrose)
Supplementation: Thyroid, B-complex, magnesium, potassium, b3 (low dose 3-4 times daily), Vitamin D, Vitamin E and Vitamin K, Antihistamine (benedryl)
Activity: as much walking as possible

 

[Sayori]

take low dose niacinamide multiple time throughout the day for NAD+

Vitamin B3 (Niacinamide) for Skin Health and Energy

Niacinamide supplements support skin health, boost cellular energy, and protect against toxins.

purebulk.com

i take 1/64th of tsp multiple times a day everyday
View attachment 4778298
i would also recommend high vitamin C preferably from freshly squeezed orange juice and daily oyster or egg yolks for micronutrients.

T3 and T3/T4 combo product you can get from meds.com.mx/ cynoplus and cynomel

I already have nad+ peptide

 

[7zyzz7]

I already have nad+ peptide

1. Low-dose Niacinamide → NAD⁺ salvage pathway (Ray Peat approach)​

Mechanism
Niacinamide enters the NAD+ salvage pathway:

1. Niacinamide
2. → NMN (via Nicotinamide phosphoribosyltransferase, NAMPT)
3. → NAD+

Key metabolic effects

• Restores intracellular NAD⁺ pools used by:
  • Sirtuins
  • PARP enzymes
  • mitochondrial dehydrogenases
• At low doses (≈25–100 mg):
  • mild NAD⁺ replenishment
  • inhibits lipolysis via reduced cAMP/PKA signaling
  • lowers circulating free fatty acids

Ray Peat rationale
Ray Peat favored small doses because:

• stabilizes mitochondrial oxidative metabolism
• avoids excess NAD⁺ turnover → methyl drain
• prevents strong inhibition of fat oxidation seen at large doses.

This is essentially metabolic regulation, not aggressive NAD boosting.

2. NAD⁺ peptide / injectable NAD⁺ strategies​

“NAD peptides” typically refer to compounds aimed at directly elevating NAD⁺ signaling, sometimes paired with peptides that affect mitochondrial function.

Mechanistic differences:

A. Direct NAD⁺ delivery​

Exogenous **NAD+ or precursors bypass rate-limiting NAMPT steps.

Effects:

• rapid rise in cellular NAD⁺
• stronger activation of Sirtuins
• increased mitochondrial biogenesis signaling (PGC-1α axis)

But:

• transient spike → faster degradation by CD38 enzymes
• can increase NAD⁺ turnover stress.

B. Peptide-linked mitochondrial signaling​

Some NAD-focused peptides indirectly affect:

• mitochondrial unfolded protein response
• oxidative phosphorylation regulation
• mitochondrial DNA repair

This is more biohacking / longevity signaling than basic metabolic support.

---

Core biochemical difference​

Feature	Niacinamide (low dose)	NAD peptide / NAD injection
pathway	endogenous salvage pathway	exogenous NAD⁺ elevation
rate control	regulated by NAMPT	bypasses regulation
metabolic tone	stabilizing / anti-lipolytic	stimulatory / signaling
NAD dynamics	gradual restoration	acute spike + turnover

---

In simple terms

• Niacinamide: slow NAD maintenance
• NAD peptides/injections: rapid NAD signaling spike

 

[Sayori]

1. Low-dose Niacinamide → NAD⁺ salvage pathway (Ray Peat approach)​

Mechanism
Niacinamide enters the NAD+ salvage pathway:

1. Niacinamide
2. → NMN (via Nicotinamide phosphoribosyltransferase, NAMPT)
3. → NAD+

Key metabolic effects

• Restores intracellular NAD⁺ pools used by:
  • Sirtuins
  • PARP enzymes
  • mitochondrial dehydrogenases
• At low doses (≈25–100 mg):
  • mild NAD⁺ replenishment
  • inhibits lipolysis via reduced cAMP/PKA signaling
  • lowers circulating free fatty acids

Ray Peat rationale
Ray Peat favored small doses because:

• stabilizes mitochondrial oxidative metabolism
• avoids excess NAD⁺ turnover → methyl drain
• prevents strong inhibition of fat oxidation seen at large doses.

This is essentially metabolic regulation, not aggressive NAD boosting.

2. NAD⁺ peptide / injectable NAD⁺ strategies​

“NAD peptides” typically refer to compounds aimed at directly elevating NAD⁺ signaling, sometimes paired with peptides that affect mitochondrial function.

Mechanistic differences:

A. Direct NAD⁺ delivery​

Exogenous **NAD+ or precursors bypass rate-limiting NAMPT steps.

Effects:

• rapid rise in cellular NAD⁺
• stronger activation of Sirtuins
• increased mitochondrial biogenesis signaling (PGC-1α axis)

But:

• transient spike → faster degradation by CD38 enzymes
• can increase NAD⁺ turnover stress.

B. Peptide-linked mitochondrial signaling​

Some NAD-focused peptides indirectly affect:

• mitochondrial unfolded protein response
• oxidative phosphorylation regulation
• mitochondrial DNA repair

This is more biohacking / longevity signaling than basic metabolic support.

---

Core biochemical difference​

Feature	Niacinamide (low dose)	NAD peptide / NAD injection
pathway	endogenous salvage pathway	exogenous NAD⁺ elevation
rate control	regulated by NAMPT	bypasses regulation
metabolic tone	stabilizing / anti-lipolytic	stimulatory / signaling
NAD dynamics	gradual restoration	acute spike + turnover

---

In simple terms

• Niacinamide: slow NAD maintenance
• NAD peptides/injections: rapid NAD signaling spike

 

[7zyzz7]

View attachment 4778323

 

[midfacedeficient]

200's barely noticeable. just dump it all 20min before bed and u'll probably be fine in the morning. definitely by lunch

 

[VrillFatNoob24]

i dont mean to be an annoying faggot BUT....

Everybodys tolerance to it is different, some can run 600mg and be fine and some can be in 200 mg and in extreme pain

 

[orbitro]

m

Cycle length:
12 days

Dosing:
200 mg daily

Goal:
lose 10 pounds of fat min

What I expect from this thread:
Tag people you know who have used dnp
So, they can tell me about their experience after

My experience after my first dnp cycle:
I would get tired fast
example: walking upstairs would gas me

Life fuel:
all the post dnp sides are gone now I feel great

tags:
@orbitro @goku21 @Canthus
@Grievous and his pooks @Starborn



​

Mirin

 

[@@@]

bump

@@@@

Mirin, get your vitamins in so you don't get cataracts/PN, you won't anyways

 

[Sayori]

Mirin, get your vitamins in so you don't get cataracts/PN, you won't anyways

Yeah with 12 days of use I'm not going to get it

 

[v.3ex]

Cycle length:
12 days

Dosing:
200 mg daily

Goal:
lose 10 pounds of fat min

What I expect from this thread:
Tag people you know who have used dnp
So, they can tell me about their experience after

My experience after my first dnp cycle:
I would get tired fast
example: walking upstairs would gas me

Life fuel:
all the post dnp sides are gone now I feel great

tags:
@orbitro @goku21 @Canthus
@Grievous and his pooks @Starborn


​

bump