Semax & Selank for derealization

[doomed.svd]

should I hop on both?
Been having derealization for a long time and it has legit ruined my life, if anyone could help

 

[maki3]

What has caused it for you?

 

[doomed.svd]

What has caused it for you?

anxiety

 

[bobowilliams]

Selank is better for anxiety.

Studies suggest Selank interacts with GABA_A receptors, acting somewhat like benzodiazepines but without the typical sedating effects. Instead of causing drowsiness, Selank tends to maintain normal wakefulness. Some research even suggests it may increase activity in orexin systems, which are associated with alertness.

• Selank also affects serotonin and dopamine signaling, altering the levels and metabolism of these neurotransmitters. In addition, it appears to influence the expression of genes involved in monoamine receptors and transporters.
• Interestingly, Selank also increases BDNF expression in the hippocampus, similar to Semax. It can inhibit enzymes that break down enkephalins, which are natural peptides involved in pain regulation and mood.
• Because Selank is derived from tuftsin, it also has immune-modulating properties. Studies show it can influence cytokines such as IL-6 and shift the balance of certain T-helper immune responses.
• Overall, Selank’s profile tends to look anxiolytic and regulatory, while Semax is more nootropic and neuroprotective.
• Selank consistently shows anxiolytic effects in animal models and appears to relieve anxiety in human studies at levels comparable to mild benzodiazepines
• One relative of Semax works differently - this peptide eases worry while keeping alertness intact. Instead of drowsiness, it brings mental clarity through stress reduction. People frequently pair it alongside Semax for combined effects. Together, they balance concentration with a steady mood. This mix supports performance in settings demanding presence without tension. Sharp thinking stays possible even under pressure. Just like Semax, the dosage matches closely. Either through nose spray or injection. Stops anytime without symptoms. Body does not grow reliant.
  
  
  

 

[Surrender]

Selank is better for anxiety.

Studies suggest Selank interacts with GABA_A receptors, acting somewhat like benzodiazepines but without the typical sedating effects. Instead of causing drowsiness, Selank tends to maintain normal wakefulness. Some research even suggests it may increase activity in orexin systems, which are associated with alertness.

• Selank also affects serotonin and dopamine signaling, altering the levels and metabolism of these neurotransmitters. In addition, it appears to influence the expression of genes involved in monoamine receptors and transporters.
• Interestingly, Selank also increases BDNF expression in the hippocampus, similar to Semax. It can inhibit enzymes that break down enkephalins, which are natural peptides involved in pain regulation and mood.
• Because Selank is derived from tuftsin, it also has immune-modulating properties. Studies show it can influence cytokines such as IL-6 and shift the balance of certain T-helper immune responses.
• Overall, Selank’s profile tends to look anxiolytic and regulatory, while Semax is more nootropic and neuroprotective.
• Selank consistently shows anxiolytic effects in animal models and appears to relieve anxiety in human studies at levels comparable to mild benzodiazepines
• One relative of Semax works differently - this peptide eases worry while keeping alertness intact. Instead of drowsiness, it brings mental clarity through stress reduction. People frequently pair it alongside Semax for combined effects. Together, they balance concentration with a steady mood. This mix supports performance in settings demanding presence without tension. Sharp thinking stays possible even under pressure. Just like Semax, the dosage matches closely. Either through nose spray or injection. Stops anytime without symptoms. Body does not grow reliant.
  
  

thanks chat gpt

 

[81xa]

that wont do shit, look for propanolol or pregabalin

 

[bobowilliams]

that wont do shit, look for propanolol or pregabalin

Depends on the person. Also depends what you take it with. Here's one user:

I started taking 500mcg Selank subcutaneously with each Ritalin dose.

• This changed EVERYTHING.
• No more 'euphoric' feeling: The weird rush is gone.
• No more hyperfocusing on the wrong thing: The focus is still there, but I can steer it now.
• No more anxiety: This is the big one. I've been so calm, while still being alert and able to focus. It's like Ritalin makes my focus levels explode, and Selank stops it from spilling over into bad side effects.
• The Eye Contact Flip:
• Before, I could never make eye contact. Now I struggle with not breaking eye contact. It's completely switched. I can actually form sentences and talk to people like a normal human being.

Maybe he's exaggerating. Other users:

• SELANK did nothing for me with 2 sprays, nothing with 4 sprays, but I noticed it was 6 sprays (3 in each nostril)
• I went to prom on 400mcg of Selank. Honestly I thought it would do absolutely nothing but it worked decent enough at lowering my inhibition. I was able to dance and talk to girls easier and conversation started to flow better.
• yeah i've gone through 8 vials of this shit and it does nothing to me. Maybe i'm built different It didn't lower my inhibition it just made me slightly drowsy and i could see colors better lol.

Seems to be hit or miss. Here's the official mean rating of r/Nootropics:

Dexedrine, adderall, ritalin, modafinil, phenibut, psilocybin seem to be the best.