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6ft8InTheNetherlands
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Estrogen produced by aromatization of gonadal androgen has an important facilitative role in male-typical aggressive behavior that is mediated through its interaction with estrogen receptors (ER) in the brain. Isoflavones found in soybeans and soy-based dietary supplements bind ER and have dose- and tissue-dependent effects on estrogen-mediated responses. Yet, effects of isoflavone-rich diets on social and aggressive behavior have not been studied. We studied the effects of long-term (15 months) consumption of diets rich in soy isoflavones on spontaneous social behavior among adult male cynomolgus macaques (Macaca fascicularis) (n = 44) living in nine stable social groups. There were three experimental conditions which differed only by the source of dietary protein: casein and lactalbumin (no isoflavones), soy protein isolate containing 0.94 mg isoflavones/g protein, and soy protein isolate containing 1.88 mg isoflavones/g protein. In the monkeys fed the higher amount of isoflavones, frequencies of intense aggressive (67% higher) and submissive (203% higher) behavior were elevated relative to monkeys fed the control diet (P's < 0.05). In addition, the proportion of time spent by these monkeys in physical contact with other monkeys was reduced by 68%, time spent in proximity to other monkeys was reduced 50%, and time spent alone was increased 30% (P's < 0.02). There were no effects of treatment on serum testosterone or estradiol concentrations or the response of plasma testosterone to exogenous gonadotropin-releasing hormone (GnRH). The results indicate that long-term consumption of a diet rich in soy isoflavones can have marked influences on patterns of aggressive and social behavior.
Link to study: https://www.researchgate.net/public..._of_diets_rich_in_soy_protein_and_isoflavones
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This study put a group of mice on a low phytoestrogenic diet and kept the other one on a soy based diet. The soy group displayed more social and aggressive behavior.
Further, mice on low-phyto diet displayed a decrease in sociability and a reduced preference for social odors, indicating a general disturbance of social behavior.
STUDY: Dietary phytoestrogens modulate aggression and activity in social behavior circuits of male mice.
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Could the aggression be caused by an increase in estrogen and as a result cause more submissive behavior?
Link to study: https://www.researchgate.net/public..._of_diets_rich_in_soy_protein_and_isoflavones
---------------------------
This study put a group of mice on a low phytoestrogenic diet and kept the other one on a soy based diet. The soy group displayed more social and aggressive behavior.
Further, mice on low-phyto diet displayed a decrease in sociability and a reduced preference for social odors, indicating a general disturbance of social behavior.
STUDY: Dietary phytoestrogens modulate aggression and activity in social behavior circuits of male mice.
-----------------------------
Could the aggression be caused by an increase in estrogen and as a result cause more submissive behavior?
