Starting my first 500 mg testosterone cycle need an ancillary interaction check

God_Fearing_Virgin

God_Fearing_Virgin

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Daily:

- Eplerenone 50 mg
- Telmisartan 40 mg
- Ezetimibe 10 mg
- Rosuvastatin 10 mg
- Nebivolol 5 mg
- Cialis 5 mg
- Dutasteride 2.5mg
- Oral minoxidil 5mg
- RU58841
- Accutane 5mg


Not daily:

- Empagliflozin or dapagliflozin EOD
- HCG 3× weekly
- HMG 1× weekly
- Aromasin only for high-estrogen symptoms
- Cerebrolysin
- Semax + Selank




My main concerns are:

- Eplerenone + telmisartan: hyperkalemia and kidney injury

- All BP lowering drugs together Telmisartan + eplerenone + oral minoxidil + nebivolol + Cialis + empagliflozin/dapagliflozin: severe hypotension, fainting and kidney injury

Any experienced roidcel bhai know how are these risks normally managed safely? Is regular potassium, creatinine/eGFR, BP and heart rate monitoring enough, or are some of these BP medications redundant.
 
Solution
midfacedeficient
i was asked for advice here so i'm gunna give what i got, dont get mad if it's imperfect (it is), and remember it's just my opinion; you don't have to care about it at all.

heres what i think a more standard approach for a newer guy running 500 test would look like.
out of your daily's you listed,

id keep:
Telmisartan 40 mg
-make this your go-to for blood pressure.
-its also a mild mysostatin inhibitor.
-its very hard to go wrong taking this as a normal person on cycle who isnt anemic or something.
-buy the 80's. want 40? bite it in half. but everyone that blasts ends up blasting more eventually, whether its mid cycle or the next cycle that they said would never happen 😵. so when u inevitably get there, if u need 80's you'll have...
i was asked for advice here so i'm gunna give what i got, dont get mad if it's imperfect (it is), and remember it's just my opinion; you don't have to care about it at all.

heres what i think a more standard approach for a newer guy running 500 test would look like.
out of your daily's you listed,

id keep:
Telmisartan 40 mg
-make this your go-to for blood pressure.
-its also a mild mysostatin inhibitor.
-its very hard to go wrong taking this as a normal person on cycle who isnt anemic or something.
-buy the 80's. want 40? bite it in half. but everyone that blasts ends up blasting more eventually, whether its mid cycle or the next cycle that they said would never happen 😵. so when u inevitably get there, if u need 80's you'll have them. and there's probably no downside to just taking 80s now

Nebivolol 5 mg
-always good to have on hand
-if you end up having to use this on 500 test, youre likely fucked in the long run. if you get severe heart rate problems on this cycle, you either have a bad lifestyle (recreational activities 😉) or bad genetics.
-not sure why ud have to take this daily. you really shouldnt have to. just have it in case you need to

cialis 5mg
- i mean if u have ed or something. very common to come and go on various cycles. have it on hand for that; sometimes it happens. take it a couple hours before the main event btw, wont do anything if u pop it right before.
-if you want to use it for a pump, cool. i dont think it'll do that much

Dutasteride 2.5mg & Oral minoxidil 5mg
-self explanatory

Accutane 5mg
- i never had anyone close to me 🫨who ran into acne problems. except one guy, a friend from a couple states over. accutane definitely helped him with these gnarly breakouts he got on his chest and back. take it preventatively if you are prone to that

id drop these things:
RU58841
- just personally not a fan.
- can cause a lot of heart problems. taking it on cycle adds another variable into the equation when u end up having blood pressure or resting heart rate issues. thats why it never got approved.
its typically best to just drop whatever drug's causing problems than try to find another drug to cover up the symptoms. this just makes it harder to figure out which drug is causing problems so you dont know which to drop
but also, having a drug that pressures ur cardiovascular system as hard as ru while also blasting puts a lot unnecessary stress on the heart. is it really worth it for the benefits of ru? if you know for a fact if doesnt have those bad sides for u then sure. if not id drop it

the others, i just dont know what they are. not huge into the looksmaxing thing.

i wouldnt worry at all about your questions at the bottom. if you have this same sort of investment you have into these drugs into your diet and lifestyle, you'll likely go through this pretty damn healthy. if not, you have pretty bad genetics and should never blast again.
 
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Solution
What the fuck is the point of having Nebivolol AND Telmisartan. You could start off without both and monitor your BP.
 
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What the fuck is the point of having Nebivolol AND Telmisartan. You could start off without both and monitor your BP.
i'd have both on hand for sure, youd use them for totally different situations. but obviously dont just take them both every day for no reason like you said; wait til you need to.
 
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i'd have both on hand for sure, youd use them for totally different situations. but obviously dont just take them both every day for no reason like you said; wait til you need to.
imo I would switch Telmisartan to HCTZ since it reduces risk of hyperkalemia from Eplerenone. That’s a common combination to balance U&E’s. (y)
 
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imo I would switch Telmisartan to HCTZ since it reduces risk of hyperkalemia from Eplerenone. That’s a common combination to balance U&E’s. (y)
this wasnt common in my day of being friends and such with people that do these activities, but it sounds promising based on what you say so id say it's worth looking in to for op
 
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