Still shedding

[Deleted member 1100]

Closest thing I could find

Figure 3: Control hair on Day 14 (left), biotinyl-GHK treated hair on...

Download scientific diagram | Control hair on Day 14 (left), biotinyl-GHK treated hair on D14 (right). from publication: Reduction of Hair-loss: Matrikines and plant molecules to the rescue | Synopsis : Excessive hair loss in men is a multifactorial problem that needs holistic treatment. The...

www.researchgate.net

https://www.researchgate.net/publication/265411501_Reduction_of_Hair-loss_Matrikines_and_plant_molecules_to_the_rescue#pf6

I'll take a look, but it's probably due to this: "Stimulates hair cell metabolism"

An interesting hypothesis but one reason I can't fully accept the inflammation-only theory is because when castrated men are given exogenous androgens, they lose their very rapidly instead of gradually over decades as one might expect based on this idea.
Furthermore, the rates of hair loss increase as you get older, despite the fact that your androgens drop as you age.
All this suggests that it isn't the case that DHT/androgens simply cause the fibrosis/calcification process slowly over time as a constant response to low-grade inflammation which then results in hair loss.

There are some connections that increasing androgens = higher arterial calcification (which could possibly mean scalp calcification)

Androgen-induced progression of arterial calcification in apolipoprotein E-null mice is uncoupled from plaque growth and lipid levels - PubMed

Arterial calcification has prognostic significance for cardiovascular outcomes, but its pathogenesis remains unclear. Calcification increases with age, but its prevalence in men suggests hormonal influence. In this study we analyzed the effect of exogenous androgens on calcification of advanced...

www.ncbi.nlm.nih.gov

The combination of DHT + Androgen Receptors + Imbalanced Calcification regulators could be the cause despite chronic inflammation not being the main trigger, could be something else as well.

 

[LordNorwood]

I'll take a look, but it's probably due to this: "Stimulates hair cell metabolism"



There are some connections that increasing androgens = higher arterial calcification (which could possibly mean scalp calcification)

Androgen-induced progression of arterial calcification in apolipoprotein E-null mice is uncoupled from plaque growth and lipid levels - PubMed

Arterial calcification has prognostic significance for cardiovascular outcomes, but its pathogenesis remains unclear. Calcification increases with age, but its prevalence in men suggests hormonal influence. In this study we analyzed the effect of exogenous androgens on calcification of advanced...

www.ncbi.nlm.nih.gov

The combination of DHT + Androgen Receptors + Imbalanced Calcification regulators could be the cause despite chronic inflammation not being the main trigger, could be something else as well.

Again that doesn't explain the lack of time-lag between androgens and hair loss in those experiments though.
I believe inflammation is a huge piece of the hair loss puzzle but its just one piece at the end of the day.

 

[Deleted member 3990]

View attachment 187724

Wtf my dad is very high T, 60 years old and has the hairline of o’pry, nothing to worry I think

the biggest meme:

DHT (T) causes hairloss


there are definitely other factors which need to be researched, and if those factors can be changed in our favour, then I think T would actually cause growth (of thick, dark hair)


What I know:
Blood flow
Inflammation
Calcification
Pathway signals