Study: Adapalene Gel (Differin) is more effective than Tretinoin

[Deleted member 2506]

Basically:

Differin doesn't need a prescription

It's cheaper

WAY less irritating

Is more effective

I've been using differin for a while and have been vouching for it but everyone says tretinoin is better so ye

Source: https://www.ncbi.nlm.nih.gov/pubmed/11843231

 

[Zdeweilx]

Prolonged use of Vitamin A derivatives cause hairloss. Stop using those products for God's sake guys

 

[Deleted member 2506]

Prolonged use of Vitamin A derivatives cause hairloss. Stop using those products for God's sake guys

NIGGA WHAT

Better have a mf source because thats retarded lol

Prolonged use of Vitamin A derivatives cause hairloss. Stop using those products for God's sake guys

just searched it up no ingredients in differin with vitamin a

 

[Zdeweilx]

NIGGA WHAT

Better have a mf source because thats retarded lol

just searched it up no ingredients in differin with vitamin a

My bad then

 

[Cope]

Adapalene is better for acne, tretinoin is better for collagen

 

[her]

Adapalene is better for acne, tretinoin is better for collagen

 

[Deleted member 2506]

Adapalene is better for acne, tretinoin is better for collagen

damn boyo u got a legit source?

p sure only dermaneedling and red light raise collagen?

 

[LordGodcat]

@benignice

 

[Cope]

damn boyo u got a legit source?

p sure only dermaneedling and red light raise collagen?

lolwat, there's studies and threads on this forum that prove this. All it takes is a simple Google search.

Restoration of Collagen Formation in Photodamaged Human Skin by Tretinoin (Retinoic Acid)

 

[Deleted member 2506]

lolwat, there's studies and threads on this forum that prove this. All it takes is a simple Google search.

Restoration of Collagen Formation in Photodamaged Human Skin by Tretinoin (Retinoic Acid)

fuck im gonna switch then collagen mogs all.

acne clears with age but collagen has to be fought to stay

 

[benignice]

I swear to the god of all things holy, the repetitiveness of these threads is going to be enough to get me to leave this site- its like banging my head against a brick wall.

Basically:

Differin doesn't need a prescription

It's cheaper

WAY less irritating

Is more effective

I've been using differin for a while and have been vouching for it but everyone says tretinoin is better so ye

Source: https://www.ncbi.nlm.nih.gov/pubmed/11843231

Adapalene doesn't need a prescription in some places. Its OTC in the USA.
Read the damn study you linked. In this case it was tested against 0.025% tretinoin on acne. This tells us nothing about the effectiveness compared to higher strength tretinoin or when used for ageing. (I'm not knocking adapalene for ageing, I happen to think its pretty damn good- I'm just making a point about the fact that none of y'all seem to read the studies that you jump on)

Prolonged use of Vitamin A derivatives cause hairloss. Stop using those products for God's sake guys

I'm gonna say this one more time: One study and some weak anecdotal evidence does not a fact make.

just searched it up no ingredients in differin with vitamin a

Yes it does. Adapalene (the active ingredient in differin) is a third generation retinoid (ie a vitamin A derivative).

Adapalene is better for acne, tretinoin is better for collagen

We simply can't say for certain that tretinoin is better than adapalene for ageing. It absolutely might be, but it also might not be. Currently tretinoin is the gold standard because we have literal decades of evidence for its use in ageing and it is only recently that adapalene has begun to be used in this way.

 

[Deleted member 2506]

I swear to the god of all things holy, the repetitiveness of these threads is going to be enough to get me to leave this site- its like banging my head against a brick wall.


Adapalene doesn't need a prescription in some places. Its OTC in the USA.
Read the damn study you linked. In this case it was tested against 0.025% tretinoin on acne. This tells us nothing about the effectiveness compared to higher strength tretinoin or when used for ageing. (I'm not knocking adapalene for ageing, I happen to think its pretty damn good- I'm just making a point about the fact that none of y'all seem to read the studies that you jump on)


I'm gonna say this one more time: One study and some weak anecdotal evidence does not a fact make.


Yes it does. Adapalene (the active ingredient in differin) is a third generation retinoid (ie a vitamin A derivative).


We simply can't say for certain that tretinoin is better than adapalene for ageing. It absolutely might be, but it also might not be. Currently tretinoin is the gold standard because we have literal decades of evidence for its use in ageing and it is only recently that adapalene has begun to be used in this way.

damn high iq rationalist ngl I will change my posting style to conform to your views

 

[Chadelite]

damn high iq rationalist ngl I will change my posting style to conform to your views

@benignice is the heavenly father for skin care

 

[benignice]

damn high iq rationalist ngl I will change my posting style to conform to your views

I wouldn't recommend that or go that far- I just have a decent amount of experience in the field.

@benignice is the heavenly father for skin care

Hahah thanks bro, although I really wouldn't go that far.

 

[Deleted member 2506]

I wouldn't recommend that or go that far- I just have a decent amount of experience in the field.

Hahah thanks bro, although I really wouldn't go that far.

Is there anything else that's effective for collagen other than Tretinion, dermaneedling, and red light therapy?

I've been doing all of them extensively coupled with aquaphor and sunscreen and squalane oil + hyaularonic acid and still only see slight gains in youth.

thnx

 

[Chadelite]

Is there anything else that's effective for collagen other than Tretinion, dermaneedling, and red light therapy?

I've been doing all of them extensively coupled with aquaphor and sunscreen and squalane oil + hyaularonic acid and still only see slight gains in youth.

thnx

ur young af your collagen is peaking rn how can you improve much

 

[benignice]

Is there anything else that's effective for collagen other than Tretinion, dermaneedling, and red light therapy?

I've been doing all of them extensively coupled with aquaphor and sunscreen and squalane oil + hyaularonic acid and still only see slight gains in youth.

thnx

You're hitting the big ones honestly.
How old are you?

 

[Seth Walsh]

Basically:

Differin doesn't need a prescription

It's cheaper

WAY less irritating

Is more effective

I've been using differin for a while and have been vouching for it but everyone says tretinoin is better so ye

Source: https://www.ncbi.nlm.nih.gov/pubmed/11843231

Yeah it's a lot better for acne. Retin-A is better for anti-aging though. They both thin out the stratum corneum which is considered bad but if you use GHK-cu in combination you will be invincible.

 

[Deleted member 2506]

You're hitting the big ones honestly.
How old are you?

just turned 18

 

[benignice]

just turned 18

....and you want to look like a child, why exactly? If you're 18 you're likely not going to get much in the realm of "anti ageing", in your case you focus should be much more on protection and prevention.

 

[eduardkoopman]

Is more effective

Effective for what???

I know Tretinoin is for acne, in essence. So better for acne, only??

But many (me included), use tratinoin NOTfor acne, but for "anti-aging". Aka, collagen maxxing, to keep elastic skin.
And how does Defferin do with Collagen maxxing??


Found a study on the aging befirtis and compassing.
Don't have time to read it. yet

https://link.springer.com/content/pdf/10.1684/ejd.2018.3320.pdf

concuslion I only time to read:
it said:
"Conclusion: Adapalene 0.3% gel showed non-inferior efficacy to tretinoin 0.05% cream as treatment for photoaged skin, with a similar safety profile. Adapalene 0.3% gel may therefore be considered a safe and effective option for the treatment of mild or moderate photoaging."

I just see. That one is also good for Collagen maxxing:

 

[RAITEIII]

You're hitting the big ones honestly.
How old are you?

You think red light the therapy works?

 

[eduardkoopman]

@5foot8Paki
@Zdeweilx

Please stop being low Iq in posts. And make this thread right.
Please backup claims with sme links, studiies, etc.
I mean, I just did a 10 minutes haisty search,because of time shortage. And I can already correct you on stuff that was said (see below)
And you Zdeweilx ; you have zero backup or depth for the balding claims.

#MakeYourPostsGreatAgain

just searched it up no ingredients in differin with vitamin a

I just checked it for you.
You were wrong.

Adapalene = a retinoid. A 3rd generation retinoid
And A retinoid = Vitamine A - devirative

Now tratinoin/Retin-A is first generation Retinoid.

I don't know if first generation or 3rd generation retinoid; have less or more effect on balding for example (or so at all)??

source:

Adapalene - Wikipedia

en.wikipedia.org

Retinoid - Wikipedia

en.wikipedia.org

 

[6ft8InTheNetherlands]

So many posts and no one mentions using them both?

I use retin a 0.025 3x a week
skinceuticals retinol once a week
effezel ( adapalene plus Benz perox) once a week
sal acid too

 

[StressShady]

Prolonged use of Vitamin A derivatives cause hairloss. Stop using those products for God's sake guys

Mon cherry, were iz your le research proof papers ?

 

[Zdeweilx]

Mon cherry, were iz your le research proof papers ?

MUH PAPERS MUH STUDIES
THIS IS UHHHMERICA

 

[StressShady]

MUH PAPERS MUH STUDIES
THIS IS UHHHMERICA

écoute ici petite me*de

 

[Hepatologyscribe]

Used Differin 0.1% gel for 2 years and Retin-A 0.05% for 6 months.

I Can tell you Retin-A is 5x more effective

(for acne)

 

[Zdeweilx]

WHERES MUH HUUUMBURGER AM HUUUUNGREY

écoute ici petite me*de

 

[benignice]

You think red light the therapy works?

I think it does as a concept, yes. In clinic and legit home devices I think do work. The shitty cheap ones you see all the time on here and the bootlegged versions? I'm less convinced about those.

 

[xico32]

Either Differin nor Tretinoin is available in Germany without a receipt. It‘s over here.

I think it does as a concept, yes. In clinic and legit home devices I think do work. The shitty cheap ones you see all the time on here and the bootlegged versions? I'm less convinced about those.

What are legit home devices? And what price range

 

[Deleted member 2506]

I think it does as a concept, yes. In clinic and legit home devices I think do work. The shitty cheap ones you see all the time on here and the bootlegged versions? I'm less convinced about those.

all the amazon ones are pure bullshit
Joovv Go Portable LED Light Therapy with Medical Grade Power

this is the best one rn

Used Differin 0.1% gel for 2 years and Retin-A 0.05% for 6 months.

I Can tell you Retin-A is 5x more effective

(for acne)

fuckk im switching

 

[7 rings]

low iq thread, tretinoin mogs

 

[Deleted member 2506]

low iq thread, tretinoin mogs

i have learned indeed

 

[Deleted member 6963]

....and you want to look like a child, why exactly? If you're 18 you're likely not going to get much in the realm of "anti ageing", in your case you focus should be much more on protection and prevention.

Sorry for necroposting, but do you know how much Vitamin A gets absorbed and goes systemic if applied topically in form of tretinoin, retinol or a retinoid?
Is hypervitaminosis A a real possibility/ danger if you just apply it to your face?

Thanks in advance.