Study: Minoxidil Acts as an Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression

[Deleted member 773]

Minoxidil Acts as an Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line - PubMed

Although more than three decades have passed since the first use of minoxidil in androgenetic alopecia (AGA), its mechanisms of action have still not been comprehensively understood. 5α-reductase (5α-R) has an active role as the predominant enzyme in both AGA and female pattern hair loss (FPHL)...

www.ncbi.nlm.nih.gov

 

[LordNorwood]

I knew there must be more to it in terms of its use against MPB than just as a vasodilator.

 

[FatJattMofo]

never using that shit in my life

 

[auboutduprecipice]

dont care would rather not have sex than be bald

 

[Deleted member 773]

dont care would rather not have sex than be bald

Hair is overated tbh.

Things more imporant than hair:

Collagen

Working dick

Fuck Min and Fin and all that reddit cope shit.

 

[mitodrake]

I would look good with full beard, would cover my failos, but also i'm afraid to use minoxdil

 

[Deleted member 773]

I would look good with full beard, would cover my failos, but also i'm afraid to use minoxdil

Dont use it

 

[mitodrake]

Dont use it

Any other tip for get better beard? I really look better with stubble

 

[Deleted member 773]

Any other tip for get better beard? I really look better with stubble

Peppermint oil dermaroller

 

[mitodrake]

Peppermint oil dermaroller

I never heard of it... i have blonde hair folicles on all my face but they dont grow, i'm low t?

 

[DOggo]

''Notably, at the highest concentration, cell growth was suppressed to a level comparable to that observed in the absence of DHT. '' The highest concentration is DHT + 1 mM Minoxidil. 1 mM Minoxidil is equal to 0,209 grams (or 209 mg). The amount we apply is 5% minox 1 mL (per application), which is 50 mg/mL. So you apply 100 mg per day. This is half of the amount where they noticed the same effects in the cells as if they had no DHT. Note that you apply this amount over your whole hair area, so the concentration is even lower, because the dish with cells is different from your skin (you apply less minox per cell than in the study). You should always see what the study means in real life and if it's actually realistic that it has the exact same effects on you.

 

[Deleted member 773]

''Notably, at the highest concentration, cell growth was suppressed to a level comparable to that observed in the absence of DHT. '' The highest concentration is DHT + 1 mM Minoxidil. 1 mM Minoxidil is equal to 0,209 grams (or 209 mg). The amount we apply is 5% minox 1 mL (per application), which is 50 mg/mL. So you apply 100 mg per day. This is half of the amount where they noticed the same effects in the cells as if they had no DHT. Note that you apply this amount over your whole hair area, so the concentration is even lower, because the dish with cells is different from your skin (you apply less minox per cell than in the study). You should always see what the study means in real life and if it's actually realistic that it has the exact same effects on you.

Well I was a dumbass and squirted like 4 caps at once immediately after dermarolling so guess I deserve my suffering.

 

[DOggo]

Well I was a dumbass and squirted like 4 caps at once immediately after dermarolling so guess I deserve my suffering.

I was looking around and it seems the effect is only apparent to the area you apply it, i.e. the surface skin cells.

 

[LordNorwood]

Hair is overated tbh.

Things more imporant than hair:

Collagen

Working dick

Fuck Min and Fin and all that reddit cope shit.

Neither of those things is more important than hair tbh tbh ngl

 

[Deleted member 773]

I was looking around and it seems the effect is only apparent to the area you apply it, i.e. the surface skin cells.

Yes but I put it on after dermarolling AKA put it o an open wound so it went systemic for me.

 

[DOggo]

Yes but I put it on after dermarolling AKA put it o an open wound so it went systemic for me.

there's no evidence of dermarolling causing such an effect

 

[Ritalincel]