STUNTED HEIGHT

[WhoTookVendetta]

DURING 12-13 MY MOM PUT ME ON STIMULANTS LIKE METHPLYDATE FOR ADHD I THINK IT STUNTED MY PEAK VELOCITY HEIGHT FUCKK U CAN SEE IT GO DOWN THEN BACK UP AFTER STOPING IT

DID IT STUNT MY HEIGHT???

MY GROWTH CHART:

 

[WhoTookVendetta]

GUYS

 

[Zagro]

DURING 12-13 MY MOM PUT ME ON STIMULANTS LIKE METHPLYDATE FOR ADHD I THINK IT STUNTED MY PEAK VELOCITY HEIGHT FUCKK U CAN SEE IT GO DOWN THEN BACK UP AFTER STOPING IT

DID IT STUNT MY HEIGHT???

MY GROWTH CHART:
View attachment 4689842

It does stunt height but you grew decent enough despite it dw

 

[o_Owtf]

Would methylphenidate be an approved treatment for ADHD if it had such an effect? Stunted growth is taken very seriously by most drug regulatory institutions. It's more likely that you've just had multiple growth spurts, which is not uncommon during puberty.

 

[Zagro]

Would methylphenidate be an approved treatment for ADHD if it had such an effect? Stunted growth is taken very seriously by most drug regulatory institutions. It's more likely that you've just had multiple growth spurts, which is not uncommon during puberty.

Methylphenidate Promotes Premature Growth Plate Closure: In Vitro Evidence - PMC

It is well known that patients with attention deficit hyperactivity disorder treated with stimulants, such as methylphenidate hydrochloride (MPH), have reduced height and weight. Even though MPH has an anorexigenic effect, an additional impact of ...

pmc.ncbi.nlm.nih.gov

 

[WhoTookVendetta]

Methylphenidate Promotes Premature Growth Plate Closure: In Vitro Evidence - PMC

It is well known that patients with attention deficit hyperactivity disorder treated with stimulants, such as methylphenidate hydrochloride (MPH), have reduced height and weight. Even though MPH has an anorexigenic effect, an additional impact of ...

pmc.ncbi.nlm.nih.gov

Im gonna fucking kill my doctor that gave me that shit my growth plates fused 2yrs early

(In gta)

 

[2s2f]

Im gonna fucking kill my doctor that gave me that shit my growth plates fused 2yrs early

(In gta)

lol

 

[onzze]

Im gonna fucking kill my doctor that gave me that shit my growth plates fused 2yrs early

(In gta)

why do you have adhd tho

 

[WhoTookVendetta]

why do you have adhd tho

“why are u blind” ahh question

 

[ccwb]

why do you have adhd tho

What the fuck is this nigga I’m crashing out in Ramadan
@Master @LTNUser @Panchitosbroncs @Anamnesis

 

[ccwb]

“why are u blind” ahh question

“Why do u wear glasses”

 

[onzze]

“why are u blind” ahh question

i never understood people with adhd all symptoms are controllable if you just control them in right moment

 

[2s2f]

i never understood people with adhd all symptoms are controllable if you just control them in right moment

Is this MF dumb

 

[2s2f]

“Why do u wear glasses”

Who is the guy in your avi

 

[WhoTookVendetta]

i never understood people with adhd all symptoms are controllable if you just control them in right moment

High t symptoms = adhd i guess

I was crazy as a kid punching the teacher and harassing girls

 

[ccwb]

Who is the guy in your avi

Me

 

[onzze]

harassing girls

then i have adhd too

 

[o_Owtf]

Im gonna fucking kill my doctor that gave me that shit my growth plates fused 2yrs early

(In gta)

Methylphenidate Promotes Premature Growth Plate Closure: In Vitro Evidence - PMC

It is well known that patients with attention deficit hyperactivity disorder treated with stimulants, such as methylphenidate hydrochloride (MPH), have reduced height and weight. Even though MPH has an anorexigenic effect, an additional impact of ...

pmc.ncbi.nlm.nih.gov

This study is far from conclusive. This is in vitro where you continuously bathe chondrycytes directly in >10mg of methylphenidate, as opposed to in vivo where you have actual kids who take the drug. When you take the drug yourself, there is no shot that like 10-33% of the drug goes directly to your growth plates. Furthermore the drug might be processed, packaged, and delivered to cells in a different way. You can bathe cells in a lot of things that harm them or change gene expression, even if those things are safe when taken orally for instance. The researches are aware of these limitations and are very tentative in their discussion, with a lot of maybes and mights.

Methylphenidate has been used on children for 70 years, there's been more than enough time and motivation to make a retrospective study comparing kids who have have taken methylphenidate with those who haven't. In fact I checked, and there's actually been a study on this. 5718 kids ADHD kids from a 1982 cohort had their heights measured. In the abstract they say very plainly that "Our findings suggest that ADHD treatment with stimulant medication is not associated with differences in adult height or significant changes in growth."

ADHD, Stimulant Treatment, and Growth: A Longitudinal Study - PMC

There is ongoing concern that stimulant medications may adversely affect growth. In a sample of attention-deficit/hyperactivity disorder (ADHD) cases and controls from a population-based birth cohort, we assessed growth and the association between ...

pmc.ncbi.nlm.nih.gov

 

[iblamesikk]

do

DURING 12-13 MY MOM PUT ME ON STIMULANTS LIKE METHPLYDATE FOR ADHD I THINK IT STUNTED MY PEAK VELOCITY HEIGHT FUCKK U CAN SEE IT GO DOWN THEN BACK UP AFTER STOPING IT

DID IT STUNT MY HEIGHT???

MY GROWTH CHART:
View attachment 4689842

do u have a cat pfp on tiktok

 

[WhoTookVendetta]

do

do u have a cat pfp on tiktok

Yes

 

[iblamesikk]

Yes

the one with a helmet in a jet?

 

[cemkii]

Damn low key I didn’t grow much for the 12 months I was on it either did restart growth though makes you wonder

 

[gymcelld]

Ur mum was a crackhead

 

[Zagro]

This study is far from conclusive. This is in vitro where you continuously bathe chondrycytes directly in >10mg of methylphenidate, as opposed to in vivo where you have actual kids who take the drug. When you take the drug yourself, there is no shot that like 10-33% of the drug goes directly to your growth plates. Furthermore the drug might be processed, packaged, and delivered to cells in a different way. You can bathe cells in a lot of things that harm them or change gene expression, even if those things are safe when taken orally for instance. The researches are aware of these limitations and are very tentative in their discussion, with a lot of maybes and mights.

Methylphenidate has been used on children for 70 years, there's been more than enough time and motivation to make a retrospective study comparing kids who have have taken methylphenidate with those who haven't. In fact I checked, and there's actually been a study on this. 5718 kids ADHD kids from a 1982 cohort had their heights measured. In the abstract they say very plainly that "Our findings suggest that ADHD treatment with stimulant medication is not associated with differences in adult height or significant changes in growth."

ADHD, Stimulant Treatment, and Growth: A Longitudinal Study - PMC

There is ongoing concern that stimulant medications may adversely affect growth. In a sample of attention-deficit/hyperactivity disorder (ADHD) cases and controls from a population-based birth cohort, we assessed growth and the association between ...

pmc.ncbi.nlm.nih.gov

Too many words so i will DNR as it looks copy-pasted

No one cares about your height and there are hundreds of meds given to children that stunt height as long as it isn’t clinically significant 3-4cm or more no one really gives a fuck if it stunt the kids height

 

[o_Owtf]

Too many words so i will DNR as it looks copy-pasted

No one cares about your height and there are hundreds of meds given to children that stunt height as long as it isn’t clinically significant 3-4cm or more no one really gives a fuck if it stunt the kids height

Bitch you fucking sent a 6 page study to me and you can't read 2 paragraphs jfl

 

[WhoTookVendetta]

Ur mum was a crackhead

I hate her so much

 

[gymcelld]

I hate her so much

Brutal up growing pill

 

[Zagro]

Bitch you fucking sent a 6 page study to me and you can't read 2 paragraphs jfl

Okay i took a singular second and already see a fault you made retard

“In fact I checked, and there's actually been a study on this. 5718 kids ADHD kids from a 1982 cohort had their heights measured. In the abstract they say very plainly that "Our findings suggest that ADHD treatment with stimulant medication is not associated with differences in adult height or significant changes in growth."“

1982 cohort but let’s skip that, tell me what this was based on? PAH? “clinically insignificant decrease” so there is a decrease , but muhh “clinically insignificant”.

You also cant just conclude things from random studies back from when you were still a zygote, it is proven mechanistically that it stunts height

 

[Panchitosbroncs]

What the fuck is this nigga I’m crashing out in Ramadan
@Master @LTNUser @Panchitosbroncs @Anamnesis

Nigga why you @ in this shit ass threads

 

[o_Owtf]

Okay i took a singular second and already see a fault you made retard

What was the fault I made? You said that there was some fault but I seriously scratching my head as to what you're trying to communicate when reading your reply. This is not me being facetious, I'm not perfect and I'm not afraid to own up to mistakes

1982 cohort but let’s skip that

Wtf is the problem with a 1982 cohort? Do you think millenials are aliens? In 2014 when this study was made it made them 32 years old.

tell me what this was based on? PAH?

What is PAH?

Also send the study i can claim random shit aswell

I already sent the study, it's in the bottom of #18. If you couldn't find it the first time I have no hopes of you reading it either way, but here it is again.

it is proven mechanistically that it stunts height

It has not been proven, the researchers to the study you linked themselves acknowledge that it is not proven. They say that it MAY explain growth retardation that has been seen in MPH users, and crucially they do not say that it explains final height differences. Maybe because those differences are very unlikely to exist in the first place, as per the study I linked you.

 

[Zagro]

What was the fault I made? You said that there was some fault but I seriously scratching my head as to what you're trying to communicate when reading your reply. This is not me being facetious, I'm not perfect and I'm not afraid to own up to mistakes


Wtf is the problem with a 1982 cohort? Do you think millenials are aliens? In 2014 when this study was made it made them 32 years old.


What is PAH?


I already sent the study, it's in the bottom of #18. If you couldn't find it the first time I have no hopes of you reading it either way, but here it is again.


It has not been proven, the researchers to the study you linked themselves acknowledge that it is not proven. They say that it MAY explain growth retardation that has been seen in MPH users, and crucially they do not say that it explains final height differences. Maybe because those differences are very unlikely to exist in the first place, as per the study I linked you.

Waste of time honestly, this is the most retarded reply I’ve gotten so far this week “what is PAH” “wtf is the problem with a study made 50 years ago?” “What was the fault?” And then quotes the fucking fault i pointed out nigga what

I also quoted a line from the study you provided which says “CLINICALLY INSIGNIFICANT DECREASE”

Translating

Decrease in final height

 

[o_Owtf]

Waste of time honestly, this is the most retarded reply I’ve gotten so far this week “what is PAH” “wtf is the problem with a study made 50 years ago?” “What was the fault?” And then quotes the fucking fault i pointed out nigga what

2026 - 2014(publication date) = 12 years, not 50 years

If you have some serious smoking gun fault that you found then you should have no problems elaborating right? Or maybe the reason why you're being so vague and unstructured in your replies is because you don't have any argument against me.

Just saw your edit. Clinically insignificant decrease means just that, insignificant, beneath any reasonable person's notice. Not attributable to the drug. But you're not a reasonable person, you're grasping at thin air desperately trying to win an internet argument lol.

 

[Zagro]

2026 - 2014(publication date) = 12 years, not 50 years

If you have some serious smoking gun fault that you found then you should have no problems elaborating right? Or maybe the reason why you're being so vague and unstructured in your replies is because you don't have any argument against me.

You don’t know anything about the body itself that’s where the issue comes from

Stimulants stunt height and this is water, even caffeine stunts height and you’re here talking about how they don’t while the study you sent shows a decrease in height? You don’t even know what predicted adult height is and how big the margin of error is.

You have no idea of how growth works or any topic at all to make such claims, do you think that it’s personal? That I’m stubborn? I would have been snorting meth right this second and getting my hands on every stimulant but i wont for obvious reasons; stunting height

The low effort in my replies is simply because i do NOT give a single fuck about anyone on this forum, if you don’t want to believe me or don’t hear the answer you wanted to hear go on and do it, it’s not like i give a fuck if you end up stunting your height

 

[o_Owtf]

The low effort in my replies is simply because i do NOT give a single fuck about anyone on this forum

 

[Zagro]

View attachment 4689965

Where counter-argument dumb ass nigga

Take the loss like the good boy you are

 

[o_Owtf]

Where counter-argument dumb ass nigga

Take the loss like the good boy you are

What do you mean "loss"? Is that what you think the point of a debate is, winning? Debates are about reaching truth. Thinking of it as a battle is such an infantile, stubborn-underdeveloped-brain way of looking at it. With your language it's obvious that you're emotionally invested in this. If all you care about is calling yourself a winner then sure, continue being factually incorrect, deprived of a potentially fruitful conversation that you just kept dismissing. And crown yourself the title of "winner." lol

 

[Zagro]

What do you mean "loss"? Is that what you think the point of a debate is, winning? Debates are about reaching truth. Thinking of it as a battle is such an infantile, stubborn-underdeveloped-brain way of looking at it. With your language it's obvious that you're emotionally invested in this. If all you care about is calling yourself a winner then sure, continue being factually incorrect, deprived of a potentially fruitful conversation that you just kept dismissing. And crown yourself the title of "winner." lol

Yes

It isn’t that deep bro you don’t have to write a paragraph with perfect grammar it’s obvious that you yourself are emotionally invested and as I’ve said i don’t care

Nigga called me stubborn as if he wasn’t calling me a bitch a few minutes ago, you were the stubborn one even with evidence, you neglected the fucking decrease in height in the study YOU provided

“Factually incorrect” accept it faggot or counter-argument me, you stopped for a reason innit

 

[o_Owtf]

Yes

It isn’t that deep bro you don’t have to write a paragraph with perfect grammar it’s obvious that you yourself are emotionally invested and as I’ve said i don’t care

Nigga called me stubborn as if he wasn’t calling me a bitch a few minutes ago, you were the stubborn one even with evidence you neglected, the fucking decrease in height in the study YOU provided

“Factually incorrect” accept it faggot or counter-argument me, you stopped for a reason innit

Is it difficult to write with good grammar? I find it comes quite naturally. By language I wasn't referring to profanity, I have no problems with that, every time you call me "retard" serves to weaken your point. I was referring to the way you're emotionally charged. I didn't neglect your evidence, I went through it carefully and brought up several counter arguments that you have yet to adress. Things like "this is in vitro", "the reserachers themselves never claimed that it explains any potential difference in adult final height."

If you're not willing to accept that "statistically insignificant decrease" means "there was no decrease in final adult height attributable to methyl phenidate" (which is true, this is scientific language that actually means this) then we'll continue this debate in a few years when your brain is more developed.

 

[Jesus_ist_König]

It does stunt height but you grew decent enough despite it dw

Based. The difference is like 1 cm at final height

 

[Zagro]

If you're not willing to accept that "statistically insignificant decrease" means "there was no decrease in final adult height attributable to methyl phenidate"

???

What kind of delusion is this I’m curious? When it’s clinically insignificant (up to 1-2 inches can be called insignificant btw) they can say it caused no decrease

This is something I’ve seen with isotretinoin trials aswell, they can state that there is no decrease in height in the abstract but if you take a singular minute to check the results you can see up to 2cm decrease in height

Stimulants stunt height this is literally water, why are we even arguing? If you want to continue you should know that continuous concentrations do not mean bathing it in methylphenidate? You can replicate those concentrations if you just use that same dose or the dose to reach “x” amount of concentration

Its very obvious if you know which receptors it effects and the downstream effects of those receptors

Let’s genuinely debate about this I’m curious and i wont bark like a dog and throw slurs the whole time as much as everything triggers me 10-fold on roids but thats no excuse

 

[o_Owtf]

Let’s genuinely debate about this I’m curious and i wont bark like a dog and throw slurs the whole time as much as everything triggers me 10-fold on roids but thats no excuse

Alright, I'll try my best as well.

When you say "clinically insignificant differences" it has a pretty precise meaning. Let's say you have 500 adult men, and you divide them into two groups of 250. If you check the average heights of each group respectively, even if they've lived comparable lifestyles and have similar genetic material, there is bound to be some difference. Let's say the difference is 0.4 cm. We can actually check the likelihood that the difference between the average heights of these being greater than 0.4cm with what's called a Z-test. If you want to I can teach you the ropes if you're not used to them, otherwise I'll just show you my calculations.

sampling variability = (male height SD)*sqrt(2/N) = 7*sqrt(2/250) = 7 * 0.0894 = 0.626.
Z = 0.4/sampling variability = 0.4/0.626 = 0.64.
=>
Pr(difference >= 0.4) = 2(1 - Std_Normal_CDF(Z)) = 2(1- 0.739) = 0.52 = 52% chance.

That is to say, when you divide a group of 500 adult men into two groups then there's a 52% you'd expect at difference greater than 0.4cm. So it's not very uncommon to have a difference like that. Now, the longitudinal study that I'm referring to happens to have used a setup similar to what I was describing, 250 men who didn't take ADHD meds vs 300 men who did. The difference they found between the groups was exactly 0.4 cm, the ADHD men were 0.4 cm shorter, which is to say there's a 52% chance of happening when you just check 250 random guys against each other anyways.

The p-value you see in the rightmost column is the likelihood of a difference at least that large occuring. 56% and 29% are too likely, what if the difference was that men who took methyl phenidate were 0.4 cm taller? Would that mean to you that using stimulants during puberty definitely make you taller? In academia you'd wan't something like 5% to be considered noteworthy, 1% to be considered strong, and 0.1% to be considered very strong. A 2 cm difference in tretinoin might not be considered noteworhty because they used too few participants, but if they used 1000s of participants in each group and the difference was 2 cm then that'd be a very strong result indicating that tretinoin harms growth.

So stimulants stunting growth is not water, judging from this study you can have hundreds of participants in each group and still not see a statistically significant difference. Of course you can never truly know, you can just keep increasing the population size forever until small sub millimeter differences will become significant. I agree with you though, I can't imagine stimulants helping growth, if it has any effect at all it is most likely negative. The study you linked does show that stimulants in vitro impact genetic expressions related to early growth plate closure, which can't be a good sign. But it's very unlikely at this point that it's going to make you any shorter than 0.4 cm than you'd otherwise be, if there's a negative impact it's subtle and indirect. OP is very unlikely to have lost out on any significant growth if any at all.

 

[ICL]

DURING 12-13 MY MOM PUT ME ON STIMULANTS LIKE METHPLYDATE FOR ADHD I THINK IT STUNTED MY PEAK VELOCITY HEIGHT FUCKK U CAN SEE IT GO DOWN THEN BACK UP AFTER STOPING IT

DID IT STUNT MY HEIGHT???

MY GROWTH CHART:
View attachment 4689842

Nigga stfu. I wish i had stimulants, shit doesnt do anything against height btw

 

[Firstname.Lastname]

Not like it matters for an LLLTN