The first scientific upgrade to hair loss treatment in a generation

User28823

User28823

do not go gentle into that good night
Joined
Aug 7, 2022
Posts
33,339
Reputation
59,534
1775006903765


Two big updates from the world of hair loss treatments.

1. Clascoterone blocks androgens directly at the receptor. No systemic exposure. 539% relative improvement in hair count vs placebo in Phase 3.

2. Rezpegaldesleukin targets autoimmune hair loss at the root. Activates Treg cells to stop your immune system attacking follicles. FDA Fast Track. 28-30% reduction in alopecia severity in 36 weeks.

The old standard (minoxidil, finasteride) was discovered by accident and hasn't fundamentally changed in 30 years. Minoxidil was a blood pressure drug and Finasteride was a prostate drug. Neither was designed for hair. The two new treatments cited above, clascoterone and rezpegaldesleukin, are the first purpose-built mechanisms.
1775006926103


Research on these peptide combinations is compelling. A placebo-controlled trial on a follistatin/VEGF/KGF mixture showed 20% improvement in visible hair density at 22 weeks, sustained at one year. A separate trial on GHK showed 71.5 new hairs/cm² at six months, 7.5x over placebo.

1775006941229


@Saint Casanova
 
  • +1
Reactions: Saint Casanova, Blackpillirony, Mess and 2 others
Good thread but Rezpegaldesleukin wouldn’t be useful for norwooding which is what 99% of this forum cares about.
 
View attachment 4846036

Two big updates from the world of hair loss treatments.

1. Clascoterone blocks androgens directly at the receptor. No systemic exposure. 539% relative improvement in hair count vs placebo in Phase 3.

2. Rezpegaldesleukin targets autoimmune hair loss at the root. Activates Treg cells to stop your immune system attacking follicles. FDA Fast Track. 28-30% reduction in alopecia severity in 36 weeks.

The old standard (minoxidil, finasteride) was discovered by accident and hasn't fundamentally changed in 30 years. Minoxidil was a blood pressure drug and Finasteride was a prostate drug. Neither was designed for hair. The two new treatments cited above, clascoterone and rezpegaldesleukin, are the first purpose-built mechanisms.
View attachment 4846039

Research on these peptide combinations is compelling. A placebo-controlled trial on a follistatin/VEGF/KGF mixture showed 20% improvement in visible hair density at 22 weeks, sustained at one year. A separate trial on GHK showed 71.5 new hairs/cm² at six months, 7.5x over placebo.
View attachment 4846041

@Saint Casanova
and how u get those drugs ?
 
its bullshit. stop fucking spreading misinformation
 
  • JFL
  • +1
Reactions: IceBlueEyes and User28823
Good thread but Rezpegaldesleukin wouldn’t be useful for norwooding which is what 99% of this forum cares about.
Clascoterone is
 
  • +1
Reactions: chudpiller
Just more preventative treatments, not regrowth. baldcels are still best off w hair systems
 
  • JFL
Reactions: User28823
Just more preventative treatments, not regrowth. baldcels are still best off w hair systems
hair systems .. rather rope.

dut + ht mogs
 
Idk dawg ht seems dumb to me. Why thin out your remaining hair by spreading it out. Fake it til you make it 😂
the back of my head is so thick is doesnt even matter... wont even see it
 
  • +1
Reactions: iceturtles
Idk dawg ht seems dumb to me. Why thin out your remaining hair by spreading it out. Fake it til you make it 😂
No one cares about the back. Front and temples or it’s a wrap
 
Can always rely on us two to be awake
Thankfully my actual sleep has got better since I’ve been high dosing melatonin but still not ideal. I’ve always loved staying up though regardless
 
  • +1
Reactions: imontheloose
Thankfully my actual sleep has got better since I’ve been high dosing melatonin but still not ideal. I’ve always loved staying up though regardless
Same. Fanboying over daytime is a normie trait
 
  • +1
Reactions: Saint Casanova
both females cited and only 2. Are you female? L
 
  • Hmm...
Reactions: User28823

Similar threads

TomoIsLearning
Replies
5
Views
110
Antonlord7
Antonlord7
hax
Replies
19
Views
144
stonecold trucel
stonecold trucel
currycel67
Replies
10
Views
297
HubertSkeletrix
HubertSkeletrix
slimester
Replies
8
Views
118
copemaxingll
copemaxingll

Users who are viewing this thread

Back
Top