The guide to Nootropics

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Nootropics Guide
Brain meme 13625965


*I know there is already a BOTB guide on Nootropics this is for the giveaway*:SMILERS:
idc if water feel free to dnr
! This is not medical advice !

0. Introduction / Table of Contents
0. Introduction / Table of contents
1. Nootropics 101
2. Natural Nootropics
3. Prescription Nootropics
4. Sources


This guide will talk about the importance of Nootropics, The best Nootropics for each category (Natural, Prescription, and Synthetic), The effectiveness of the Nootropic, and the background of the Nootropic that is being talked about. This is a rushed guide so if information looks a little off please excuse it.

1. Nootropics 101
What are Nootropics and what do they do?

Nootropics are artificial and natural compounds/substances that enhance cognitive function (attention, memory, learning, reasoning, problem-solving, decision-making, etc.) Nootropics are known as "smart drugs" and they while they don't act directly by releasing neurotransmitters (chemical messengers).

They still could improve the brain’s supply of glucose and oxygen, have antihypoxic effects (prevent/mitigate from insufficient oxygen supply to tissues), and protect brain tissue from neurotoxicity (damage to the nervous system).

These substances are metabolically active, but most nootropics show no immediate effects after a single dose, requiring an extended period of use to produce results.


Nootropics will usually fall into these three categories:

1. Natural supplements
These are all over the counter things you could buy off of amazon.
These supplements are mostly known for things like caffeine, creatine, ashwagandha, ginseng, bacopa monnieri, etc.
While considered safer then other options of Nootropics it lacks bulletproof medical evidence for actual significant cognitive enchantments.
Most effects for the natural supplements will be subtle or will need to cumulate to really do something.

2. Prescription drugs
Prescription drugs are FDA approved and while are used for people with conditions people can still use them with risks of cardiovascular side effects.
These are known for Ritalin, Adderall ( more of a prescription stimulant but basically a nootropic) , Bromantane, and Nardil
Are known for being more effective then natural supplements but carry more possible risks

3. Synthetic Compounds
I will not be talking about synthetic compounds much
Most synthetic compounds are not FDA approved and are unregulated substances
These are known for Racetams, Noopept, (and also Ritalin and Adderall but they are prescription drugs)

Know that you know most of the basics lets get into the Nootropics.

2. Natural Nootropics

2.1- Caffeine

Caffeine is the most popular Nootropic commonly found coffee, energy drinks, tea, and most chocolate based candies. Caffeine has a more of an acute cognitive
effect. But it still increases alertness, attention, and enhanced performance on memory tasks.
Caffeine exerts its effects by blocking adenosine receptors A1 (in the brain, heart, kidneys) and A2A ( found in the basal ganglia).
The effects from the blockade of A1 receptors seems to diminish with chronic exposure, but there may be residual effects that are mediated through A2A receptors.

2.2- Ashwagandha

Ashwagandha is a herb from India that has been used for 1000+ years.

It has been shown to be a reliable anxiety reducer. :lulWut:
Also shown to have increase some aspects of attention but that's not well studied.
Ashwagandha seems to have GABA-mimetic activity (imitate the effects of the inhibitory neurotransmitter), which may account for its anxiolytic effects (reduction of anxiety).

2.3- L-Theanine

L-Theanine is one of the main psychoactive compounds (chemical substances) found in tea.

L-theanine is extremely safe and has been shown to mitigate the negative aspects of caffeine, such as anxiety, increased blood pressure and diminished sleep quality, while possibly improving upon the positive aspects.
L-theanine taken with caffeine is one of the most reliable and safe nootropic stacks for improving focus.:BoolinJAM:

4. Prescription Nootropics

3.1- Adderall

Used for people with ADHD. Adderall is used for a focus and attention.
Sadly I could not find any studies that prove it helps non ADHD people so this does not really improve cognitive function for the neurotypical brain (usually).
But there is 1000s of non ADHD people that swear by Adderall and will say that is a good nootropic for focus.
For neurotypical people Adderall is seemed to be more effective in boost energy, interest, enjoyment, and optimism about the task at hand.

3.2- Ritalin
1783678515145
:feelskek:


The drug works by increasing the concentration of certain neurotransmitters in the brain that control reasoning, problem solving and other behaviors.
Again I could not find any studies that say it does the same for non ADHD people.
But just like Adderall there is countless people on reddit and other forums that swear Ritalin is their savior and helps them focus while studying.
Just like Adderall the only thing that was shown through studies is that it is more effective in boost energy, interest, enjoyment, and optimism about the task at hand.


4. Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC4480845/
Ik some are not the best sources:COPIUM:

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