theory on doing leg length-limb while taking abaloparatide-Teriparatide.

[KLEORB]

A theoretical Conspiracy's not even a conspiracy at this point. since both of these anabolic agents are both becoming more mainstreamed. I have good hopes to say both of these osteoblast Beast's Will help anyone willing to get a LL, (Limb/leg Lengthening) on many circumstances' due to the factual reason that Teriparatide is a recombinant form of PTH aka (1-34), and it has been shown to stimulate bone formation in individuals with osteopenia or osteoporosis. and Abaloparatide is a synthetic analog of parathyroid hormone-related protein AKA the PTHrP which also promotes bone formation, but with potentially a different mechanisms compared to teriparatide. and since Limb lengthening surgeries involve creating a small gap between bone segments and then gradually distracting stretching them, allowing new bone to form in the gap. This new bone aka the callus needs to be strong and stable to support weight bearing and functional movement.. BUT! there's some possible potential issues. One of the potential risks of limb-leg lengthening surgeries is nonunion or delayed healing but since Abaloparatide and teriparatide have been shown to improve the chances of successful union and faster healing by stimulating bone cell activity and enhancing the mineralization of new bone tissue. This can help prevent complications where the bone may not heal properly, reducing the risk of needing additional interventions or surgeries. and It's Mirin to say Both abaloparatide and teriparatide increase the differentiation and proliferation of osteoblast precursor cells, promoting the maturation of osteoblasts.. THIS is critical for bone regeneration, particularly in surgeries like limb lengthening where new bone formation is required in the distracted gap.

Lets do a comparison:

Phase	Without Medication	With Teriparatide/Abaloparatide
Pre-Surgery Preparation	1-2 months	1-2 months
Initial Healing & Callus Formation (0-2 months)	2 months. slow callus formation	0-2 months. faster callus formation
Distraction Phase (2-4 months)	2-4 months. slower bone regeneration	2-4 months. faster bone formation
Consolidation & Hardening (4-12 months)	4-12 months. slow mineralization	4-8 months. faster consolidation
Total Recovery Time	6-12 months. depending on the amount of lengthening and individual healing	4-8 months. 30% faster recovery

Let me know you're guy's thoughts. Worth it? not worth it? Save more time and more efficient for this specific surgery>?
Mirin? Not Mirin?

 

[KLEORB]

bump