Topical Spironolactone (acnecels gtfih)

.exotic4u

.exotic4u

Banned
Joined
Mar 10, 2025
Posts
257
Reputation
172
Hello roidcels (and acnecels), today we are going to talk about topical spironolactone (and how to use it). This is a informational thread not some revolutionary new method (i'm pretty sure this info is already known jfl)

Anyways lets get into it: Topical Spironolactone is extremely effective and useful when on a steroid cycle, it counters androgenic side effects (acne, shit skin texture, anti aging) from steroids and promotes skin health.

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
1750529705567



Oral Spironolactone also helps with hair loss from DHT (Dihydrotestosterone). (Though I would recommend using finasteride or dutasteride for better results.)


Why topical?? Applying topical spironolactone to skin doesn't mess with your hormone levels. (Doesn't potentially nuke testosterone).
1750529908735

Ok bhaicel but what to buy? Look for a prescription-grade topical spironolactone cream or gel (5% preferably but 2% works)
1. Clense your skin first (don't use a harsh one)
2. Apply a light drop that covers your entire face (dont use too much jfl)
3. Apply once daily (recommended at night as part of your skincare). If you use it at daytime, use SPF to prevent skin damage
(Optional) Mix with your moisturizer (make sure in the ingredients list there is niacimide or ceramides to heal the skin barrier)
Relevant studies:heart::
https://pmc.ncbi.nlm.nih.gov/articles/PMC5360829/
https://pubmed.ncbi.nlm.nih.gov/2147469/
https://pubmed.ncbi.nlm.nih.gov/24509960/
https://pubmed.ncbi.nlm.nih.gov/2972662/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
 
  • +1
Reactions: Djimo
sorry for the shit formatting i tried
 
the oral stuff fucks your AR
 
  • +1
Reactions: .exotic4u
just get accutane nigga, did wonders for me 5 years ago
 
  • JFL
Reactions: .exotic4u
Hello roidcels (and acnecels), today we are going to talk about topical spironolactone (and how to use it). This is a informational thread not some revolutionary new method (i'm pretty sure this info is already known jfl)

Anyways lets get into it: Topical Spironolactone is extremely effective and useful when on a steroid cycle, it counters androgenic side effects (acne, shit skin texture, anti aging) from steroids and promotes skin health.

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
View attachment 3848170


Oral Spironolactone also helps with hair loss from DHT (Dihydrotestosterone). (Though I would recommend using finasteride or dutasteride for better results.)


Why topical?? Applying topical spironolactone to skin doesn't mess with your hormone levels. (Doesn't potentially nuke testosterone).
View attachment 3848188
Ok bhaicel but what to buy? Look for a prescription-grade topical spironolactone cream or gel (5% preferably but 2% works)
1. Clense your skin first (don't use a harsh one)
2. Apply a light drop that covers your entire face (dont use too much jfl)
3. Apply once daily (recommended at night as part of your skincare). If you use it at daytime, use SPF to prevent skin damage
(Optional) Mix with your moisturizer (make sure in the ingredients list there is niacimide or ceramides to heal the skin barrier)
Relevant studies:heart::
https://pmc.ncbi.nlm.nih.gov/articles/PMC5360829/
https://pubmed.ncbi.nlm.nih.gov/2147469/
https://pubmed.ncbi.nlm.nih.gov/24509960/
https://pubmed.ncbi.nlm.nih.gov/2972662/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
might rape your hormones heavy tbh, hear its only for women. get better topical dht blockers (winlevi might be better and less risk profile) and block Mtor on your skin too. I wanted to try using it but id only recommend it if you're on roids and on letrozole/arimidex tbh, mtor and dht pathways are both stimulated by hgh and anabolic hormones like test/dht conversion and mTor, both are crucial for development. in some cases blocking mtor directly might have better effects on acne since pathology and all that, and if you get dry skin its better compared to having cystic acne jfl. My stack rn to manage hgh acne (when it arrives/can source it):
Winlevi 1/2x/daily
Tazarotene 0.1% 2/3week
rapamycin 0.1% 3x/week
letrozole undecided dose (height and managing potential winlevi effects
ghk-cu 3mg ED, mini breaks after 6 weeks (like 3 days)
and then will add something else for barrier restoration +ghk-cu post microneedling (once a month)
@enchanted_elixir whatchu think about it bro
 
  • +1
Reactions: natralrivers
might rape your hormones heavy tbh, hear its only for women. get better topical dht blockers (winlevi might be better and less risk profile) and block Mtor on your skin too. I wanted to try using it but id only recommend it if you're on roids and on letrozole/arimidex tbh, mtor and dht pathways are both stimulated by hgh and anabolic hormones like test/dht conversion and mTor, both are crucial for development. in some cases blocking mtor directly might have better effects on acne since pathology and all that, and if you get dry skin its better compared to having cystic acne jfl. My stack rn to manage hgh acne (when it arrives/can source it):
Winlevi 1/2x/daily
Tazarotene 0.1% 2/3week
rapamycin 0.1% 3x/week
letrozole undecided dose (height and managing potential winlevi effects
ghk-cu 3mg ED, mini breaks after 6 weeks (like 3 days)
and then will add something else for barrier restoration +ghk-cu post microneedling (once a month)
@enchanted_elixir whatchu think about it bro

might rape your hormones heavy tbh, hear its only for women. get better topical dht blockers (winlevi might be better and less risk profile) and block Mtor on your skin too. I wanted to try using it but id only recommend it if you're on roids and on letrozole/arimidex tbh, mtor and dht pathways are both stimulated by hgh and anabolic hormones like test/dht conversion and mTor, both are crucial for development. in some cases blocking mtor directly might have better effects on acne since pathology and all that, and if you get dry skin its better compared to having cystic acne jfl. My stack rn to manage hgh acne (when it arrives/can source it):
Winlevi 1/2x/daily
Tazarotene 0.1% 2/3week
rapamycin 0.1% 3x/week
letrozole undecided dose (height and managing potential winlevi effects
ghk-cu 3mg ED, mini breaks after 6 weeks (like 3 days)
and then will add something else for barrier restoration +ghk-cu post microneedling (once a month)
@enchanted_elixir whatchu think about it bro
How tf did you source winlevi
 
How tf did you source winlevi
okderma but if you're broke just buy it from navana pharma https://shombhob.com/product-details/clascon-cream, the pharmacy has low trust but okderma dropshits ts so imma just buy a fuck ton of it. Plus it seems okay-cheap compared to that. worst case scenario ill have to blow some money on a compounding pharmacy, the only thing thats missing is rapamycin (metformin is pretty copey and rapamycin literally gives MTOR its name [Mechanical target of rapamycin], metformin suppression of mtor through AMPK seems mild in comparison) since most people with skin problems would benefit yes from increased cell turnover but that breaks them out first so im putting that on pause with rapamycin when in a high glycemic state + anabolic state due to proliferation genes (high mtor expression in the skin, prone to comedones and breakout) then using a retinoid a few hours after the spike. This is my case though (becasue of roids) so you might just be okay with using oral dut or topical clascoterone. But, lose the fear of fin and dut, the side effects are psychosomatic. If you think about them too much, youll probably get them + your balls can be revived from the dead (in case you cant source clascoterone and have to resort to dut).
 
  • +1
Reactions: wtiera and natralrivers
Hello roidcels (and acnecels), today we are going to talk about topical spironolactone (and how to use it). This is a informational thread not some revolutionary new method (i'm pretty sure this info is already known jfl)

Anyways lets get into it: Topical Spironolactone is extremely effective and useful when on a steroid cycle, it counters androgenic side effects (acne, shit skin texture, anti aging) from steroids and promotes skin health.

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
View attachment 3848170


Oral Spironolactone also helps with hair loss from DHT (Dihydrotestosterone). (Though I would recommend using finasteride or dutasteride for better results.)


Why topical?? Applying topical spironolactone to skin doesn't mess with your hormone levels. (Doesn't potentially nuke testosterone).
View attachment 3848188
Ok bhaicel but what to buy? Look for a prescription-grade topical spironolactone cream or gel (5% preferably but 2% works)
1. Clense your skin first (don't use a harsh one)
2. Apply a light drop that covers your entire face (dont use too much jfl)
3. Apply once daily (recommended at night as part of your skincare). If you use it at daytime, use SPF to prevent skin damage
(Optional) Mix with your moisturizer (make sure in the ingredients list there is niacimide or ceramides to heal the skin barrier)
Relevant studies:heart::
https://pmc.ncbi.nlm.nih.gov/articles/PMC5360829/
https://pubmed.ncbi.nlm.nih.gov/2147469/
https://pubmed.ncbi.nlm.nih.gov/24509960/
https://pubmed.ncbi.nlm.nih.gov/2972662/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
gives you titties btw
 
  • +1
Reactions: natralrivers
okderma but if you're broke just buy it from navana pharma https://shombhob.com/product-details/clascon-cream, the pharmacy has low trust but okderma dropshits ts so imma just buy a fuck ton of it. Plus it seems okay-cheap compared to that. worst case scenario ill have to blow some money on a compounding pharmacy, the only thing thats missing is rapamycin (metformin is pretty copey and rapamycin literally gives MTOR its name [Mechanical target of rapamycin], metformin suppression of mtor through AMPK seems mild in comparison) since most people with skin problems would benefit yes from increased cell turnover but that breaks them out first so im putting that on pause with rapamycin when in a high glycemic state + anabolic state due to proliferation genes (high mtor expression in the skin, prone to comedones and breakout) then using a retinoid a few hours after the spike. This is my case though (becasue of roids) so you might just be okay with using oral dut or topical clascoterone. But, lose the fear of fin and dut, the side effects are psychosomatic. If you think about them too much, youll probably get them + your balls can be revived from the dead (in case you cant source clascoterone and have to resort to dut).
Thanks and you know lots about this shit lol, I just started researching topical anti androgens for skin yesterday
 
okderma but if you're broke just buy it from navana pharma https://shombhob.com/product-details/clascon-cream, the pharmacy has low trust but okderma dropshits ts so imma just buy a fuck ton of it. Plus it seems okay-cheap compared to that. worst case scenario ill have to blow some money on a compounding pharmacy, the only thing thats missing is rapamycin (metformin is pretty copey and rapamycin literally gives MTOR its name [Mechanical target of rapamycin], metformin suppression of mtor through AMPK seems mild in comparison) since most people with skin problems would benefit yes from increased cell turnover but that breaks them out first so im putting that on pause with rapamycin when in a high glycemic state + anabolic state due to proliferation genes (high mtor expression in the skin, prone to comedones and breakout) then using a retinoid a few hours after the spike. This is my case though (becasue of roids) so you might just be okay with using oral dut or topical clascoterone. But, lose the fear of fin and dut, the side effects are psychosomatic. If you think about them too much, youll probably get them + your balls can be revived from the dead (in case you cant source clascoterone and have to resort to dut).
Have you tried the one from the link ? Ima need this too if it's real.
 

Similar threads

S
Replies
19
Views
356
Gaygymmaxx
Gaygymmaxx
dancooper
Replies
10
Views
1K
6ft8pslslayer
6ft8pslslayer
ZyzzReincarnate
Replies
32
Views
1K
iblameautistickids
iblameautistickids
LightskinHtn
Replies
9
Views
660
Eren
Eren
Sachlichkeit
Discussion DHT is good
Replies
17
Views
964
Sachlichkeit
Sachlichkeit

Users who are viewing this thread

Back
Top