Tretinoin is best used periodically.

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Deleted member 30402

Zephir
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If you use it every day, your skin will dry out and will start to look wrinkly, rough, and irritated. It’s best to use it periodically. Use it for a week straight once a month in conjunction with micro-needling for collagen benefits.
 
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Reactions: Deleted member 23399
wtf never heard this kinda regime before
 
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Reactions: Deleted member 30402
I just do one day gaps in between. Fixed my irritation problems pretty well
 
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Reactions: MoggerGaston
0.05 strength tret never irritated me
 

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