Tretinoin substitute

[zeke.htn]

Adapalene Gel: Everyone should be using it​

For any chuds who don't want to buy tret from IndiaMart or pay a shit ton of money through online pharmacies, think about using adapalene gel, its basically tret but more tolerable.

It's a topical retinoid that's widely used for acne and has many of the same mechanisms as tretinoin. While it's generally a bit less potent for anti-aging, it's often easier on the skin and much easier to get.

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What Is Adapalene?​

Adapalene is a third-generation topical retinoid that:

• Increases skin cell turnover
• Helps unclog pores
• Reduces acne and prevents new breakouts
• Improves skin texture over time
• May help fade post-acne marks and provide modest anti-aging benefits

Compared to tretinoin, adapalene is formulated to be more stable and tends to cause less irritation, its great in the summer or more sunny areas, also great for people with sensitive skin.

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Tretinoin vs. Adapalene​

Feature	Tretinoin	Adapalene
Best for	Acne, photoaging, wrinkles, pigmentation	Acne, especially blackheads, whiteheads, and inflammatory acne
Strength	Generally more potent	Slightly gentler
Irritation	Higher (dryness, peeling, redness)	Lower; easier to tolerate
Availability	Prescription in many countries	0.1% gel is often available over the counter
Anti-aging evidence	Extensive, decades of research	Growing evidence, but less extensive

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How Effective Is It?​

Clinical studies have found that adapalene gel actually performs better than 0.03% tretinoin and similarly at higher concentrations for acne treatment while generally causing less irritation. If tret fries your skin or you just cant get it adapalene gel is perfect for you. Source: https://pubmed.ncbi.nlm.nih.gov/9204091/

For anti-aging, tretinoin still has the strongest long-term evidence, but adapalene also shows improvements in skin texture and photoaging over time.

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Before & After​

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Where to Buy​

Adapalene 0.1% gel is inexpensive and, in many countries, can be purchased over the counter through major retailers, I just buy my shit off Amazon for 8 dollars a container and it lasts 2-3 months.

 

[James holder]

I used to use it all over but now i use isotretinoin i find it usefull to put on potential breakouts.
Good thread i did read

 

[Awest]

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Adapalene Gel: Everyone should be using it​

For any chuds who don't want to buy tret from IndiaMart or pay a shit ton of money through online pharmacies, think about using adapalene gel, its basically tret but more tolerable.

It's a topical retinoid that's widely used for acne and has many of the same mechanisms as tretinoin. While it's generally a bit less potent for anti-aging, it's often easier on the skin and much easier to get.

---

What Is Adapalene?​

Adapalene is a third-generation topical retinoid that:

• Increases skin cell turnover
• Helps unclog pores
• Reduces acne and prevents new breakouts
• Improves skin texture over time
• May help fade post-acne marks and provide modest anti-aging benefits

Compared to tretinoin, adapalene is formulated to be more stable and tends to cause less irritation, its great in the summer or more sunny areas, also great for people with sensitive skin.

---

Tretinoin vs. Adapalene​

Feature	Tretinoin	Adapalene
Best for	Acne, photoaging, wrinkles, pigmentation	Acne, especially blackheads, whiteheads, and inflammatory acne
Strength	Generally more potent	Slightly gentler
Irritation	Higher (dryness, peeling, redness)	Lower; easier to tolerate
Availability	Prescription in many countries	0.1% gel is often available over the counter
Anti-aging evidence	Extensive, decades of research	Growing evidence, but less extensive

---

How Effective Is It?​

Clinical studies have found that adapalene gel actually performs better than 0.03% tretinoin and similarly at higher concentrations for acne treatment while generally causing less irritation. If tret fries your skin or you just cant get it adapalene gel is perfect for you. Source: https://pubmed.ncbi.nlm.nih.gov/9204091/

For anti-aging, tretinoin still has the strongest long-term evidence, but adapalene also shows improvements in skin texture and photoaging over time.

---

Before & After​

View attachment 5365491

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Where to Buy​

Adapalene 0.1% gel is inexpensive and, in many countries, can be purchased over the counter through major retailers, I just buy my shit off Amazon for 8 dollars a container and it lasts 2-3 months.

there was a study that showed improvement of acne scars with 0,3% adapalene I just cant find it anymore, it had photos in it aswell....

 

[EnzoPSL]

Good thread thx