TYRA-300 is overhyped

foidrapjst

foidrapjst

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why do i say that TYRA is overhyped? heres why.

1: it gets brutally mogged by erdafitinib
2: way too expensive (upwards of 2k/g)
3: barely any human studies
4: sourcing

now why do people actually get tyra-300?

1: extremely fgfr3 selective
but- but what does that mean bhai?
here little one, let me explain to you in simple terms.

what does fgfr3 actually mean and what does inhibiting it do?

FGFR3 (fibroblast growth factor receptor 3)
fgfr3 essentially acts as a brake on bone growth and inhibiting it basically removes that brake.

FGFR3 selectivity
erdafitinib is whats known as a "pan fgfr inhibitor" which means it targets the fgfr family (fgfr1-4)
while TYRA-300 is super selective to fgfr3. now why is inhibiting the fgfr family bad? heres why.
the side effects, the known side effects on erdafitinib include
high prosphate, diarrhea, dry mouth, constipation, abdominal pain, nausea and vomiting.
this happens why? because its a...... "pan fgfr inhibitor"

2: you can run higher dose on tyra-300, which means cleaner linear growth.

if you're running tyra-300 with a dose of 30mg and getting 2k/g it totals to around 1.8k per month. while erda usually costs around 40-100 dollars per month depending on vendor. now unless your genuinely rich i dont recommend running this, if youre that scared of side effects and want cleaner linear growth then just run infigratinib.

Screenshot 2026 09 08 130102

https://pmc.ncbi.nlm.nih.gov/articles/PMC12668719/

conclusion: run erdafitinib instead of tyra-300🚬






:feelswhy:
 
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elaborate
you can get it for like almost 1k

but im just shitposting i agree that theres better things to run for price and even ignoring that
 
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you can get it for like almost 1k

but im just shitposting i agree that theres better things to run for price and even ignoring that
ik i have a source thats like around 1k but it can be up to 2k and even more
 
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Saw erda and immediately stopped reading
Low IQ user detected:PepePls::PepePls:
 
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Saw erda and immediately stopped reading
Low IQ user detected:PepePls::PepePls:
Are you totally against FGFR3 inhibitors, or believe another is better FGFR inhibitor
 
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Both is
 
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why did you delete them?
I didn't like them at the time I posted it; FGFR3 inhibitors were extremely new and weren't mainstream, so it was the first guide on infib i believe, if im remebering it correctly
 
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I didn't like them at the time I posted it; FGFR3 inhibitors were extremely new and weren't mainstream, so it was the first guide on infib i believe, if im remebering it correctly
i thought it was useless bc @IAmBecoming183CM was hating, and so was the rest of the replies, as I mentioned it was very new
 
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why do i say that TYRA is overhyped? heres why.

1: it gets brutally mogged by erdafitinib
2: way too expensive (upwards of 2k/g)
3: barely any human studies
4: sourcing

now why do people actually get tyra-300?

1: extremely fgfr3 selective
but- but what does that mean bhai?
here little one, let me explain to you in simple terms.

what does fgfr3 actually mean and what does inhibiting it do?

FGFR3 (fibroblast growth factor receptor 3)
fgfr3 essentially acts as a brake on bone growth and inhibiting it basically removes that brake.

FGFR3 selectivity
erdafitinib is whats known as a "pan fgfr inhibitor" which means it targets the fgfr family (fgfr1-4)
while TYRA-300 is super selective to fgfr3. now why is inhibiting the fgfr family bad? heres why.
the side effects, the known side effects on erdafitinib include
high prosphate, diarrhea, dry mouth, constipation, abdominal pain, nausea and vomiting.
this happens why? because its a...... "pan fgfr inhibitor"

2: you can run higher dose on tyra-300, which means cleaner linear growth.

if you're running tyra-300 with a dose of 30mg and getting 2k/g it totals to around 1.8k per month. while erda usually costs around 40-100 dollars per month depending on vendor. now unless your genuinely rich i dont recommend running this, if youre that scared of side effects and want cleaner linear growth then just run infigratinib.

View attachment 5625834
https://pmc.ncbi.nlm.nih.gov/articles/PMC12668719/

conclusion: run erdafitinib instead of tyra-300🚬






:feelswhy:
i will not read this, 14yo “foidraper” :lul:
 
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why do i say that TYRA is overhyped? heres why.

1: it gets brutally mogged by erdafitinib
2: way too expensive (upwards of 2k/g)
3: barely any human studies
4: sourcing

now why do people actually get tyra-300?

1: extremely fgfr3 selective
but- but what does that mean bhai?
here little one, let me explain to you in simple terms.

what does fgfr3 actually mean and what does inhibiting it do?

FGFR3 (fibroblast growth factor receptor 3)
fgfr3 essentially acts as a brake on bone growth and inhibiting it basically removes that brake.

FGFR3 selectivity
erdafitinib is whats known as a "pan fgfr inhibitor" which means it targets the fgfr family (fgfr1-4)
while TYRA-300 is super selective to fgfr3. now why is inhibiting the fgfr family bad? heres why.
the side effects, the known side effects on erdafitinib include
high prosphate, diarrhea, dry mouth, constipation, abdominal pain, nausea and vomiting.
this happens why? because its a...... "pan fgfr inhibitor"

2: you can run higher dose on tyra-300, which means cleaner linear growth.

if you're running tyra-300 with a dose of 30mg and getting 2k/g it totals to around 1.8k per month. while erda usually costs around 40-100 dollars per month depending on vendor. now unless your genuinely rich i dont recommend running this, if youre that scared of side effects and want cleaner linear growth then just run infigratinib.

View attachment 5625834
https://pmc.ncbi.nlm.nih.gov/articles/PMC12668719/

conclusion: run erdafitinib instead of tyra-300🚬






:feelswhy:
tyra mogs erda but is crazy expensive
 
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tyra mogs erda but is crazy expensive
overall erda mogs imo like high dif though, it js depends if ur rich, if ur rich tyra mogs but if ur a minimum wage mcdonalds worker than erda mogs it
 
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