crewe
neurodivergent
- Joined
- Aug 5, 2026
- Posts
- 67
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- 35
Topical Rosiglitazone absolutely mogs volufiline.
What is it?:
It is a experimental skin treatment and it reduces skin fibrosis and can restore subcutaneous fat layers.
How does it work?:
When applied to the skin Topical Rosgilitazone penetrates the skin and rewrites genetic signals inside skin cells
How do you make it? *I am NOT responsible if something goes wrong you are doing this at your own RISK*
What is it?:
It is a experimental skin treatment and it reduces skin fibrosis and can restore subcutaneous fat layers.
How does it work?:
When applied to the skin Topical Rosgilitazone penetrates the skin and rewrites genetic signals inside skin cells
How do you make it? *I am NOT responsible if something goes wrong you are doing this at your own RISK*
materials
- rosiglitazone maleate powder (research chemical, 99% purity)
- DMSO (dimethyl sulfoxide) ; penetrant/carrier
- propylene glycol ; secondary solvent
- distilled water
- ethanol (optional) ; for better solubility
- 0.22µm syringe filter (sterile)
- amber glass vial, sterile
- micropipette or milligram scale
- magnetic stirrer / hot plate
- pH strips (target ~5.5)
- nitrile gloves, respirator mask (powder handling) (optional but safety bs just DNR the sides if something bad happens)
recipe (1% rosiglitazone gel)
- dissolve 100 mg rosiglitazone maleate in 1 mL DMSO + 1 mL propylene glycol under gentle heat (~40°C) and stirring.
- once fully dissolved, add 8 mL distilled water slowly while stirring.
- adjust pH to 5.5 using dilute HCl/NaOH if needed.
- optionally add 0.5 mL ethanol to final solution if cloudiness appears.
- filter through 0.22 µm syringe filter into sterile amber vial.
- store refrigerated, use within 7 days.
application
- apply 0.1–0.2 mL to target area (eyebags or wherever you may want it) once daily. this will NOT fix your recessed infraorbitals
but it can help with eyebags - no occlusion; let air dry.
