Vorinostat Alternatives for Fear Extinction

[helpmegod]

Hello,

Has anyone here tried any alternatives to Vorinostat for fear extinction?

From my research I could see that Black seed oil, Sodium Butyrate, Sulforaphane, resistant starch(??) and Berberine [1][2] are other HDAC inhibitors.

Does anyone here have any experience with other potent HDAC inhibitors that could be used as an alternative to Vorinostat?

[1]:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851465/

[2]:
https://pubmed.ncbi.nlm.nih.gov/34994284/

 

[helpmegod]

bump

 

[alpha_provider]

The ecology of human fear: survival optimization and the nervous system

We propose a Survival Optimization System (SOS) to account for the strategies that humans and other animals use to defend against recurring and novel threats. The SOS attempts to merge ecological models that define a repertoire of contextually relevant threat induced survival behaviors with...

www.frontiersin.org

dont be a delusional coper

 

[CalulArgintiu59]

To be honest, I am thinking to start an experiment with valproic acid, as I can't find enough info, but I will try different dossages because it's also a potent enough HDAC inhibitor, but it's considered a dirtier drug! Varinostat is too hard to get