Weekly Teriparatide Dose and Cortical Bone Growth

[CertifiedGoy]

Greetings niggas, I found a study suggesting weekly teriparatide dosing may preferentially increase cortical bone more than the usual daily injections.

TERABIT Trial – QCT Analysis

-Compared daily (20 µg) vs weekly (56.5 µg) teriparatide
-Weekly dosing increased cortical volumetric BMD and cortical bone volume more than daily dosing
- This suggests weekly PTH favours cortical structure which is what we want when the goal is visible bone growth
PubMed link


From what I gather Daily PTH tends to target trabecular bone (spine, vertebrae), while weekly PTH appears to favour cortical bone modelling.

Cortical gains could theoretically contribute to bone thickness/projection in areas like the mandible/chin/zygomatics. Let me know your thoughts.

@Zagro @Bitchwhipper2​

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[MaracasMogs]

Greetings niggas, I found a study suggesting weekly teriparatide dosing may preferentially increase cortical bone more than the usual daily injections.

TERABIT Trial – QCT Analysis

-Compared daily (20 µg) vs weekly (56.5 µg) teriparatide
-Weekly dosing increased cortical volumetric BMD and cortical bone volume more than daily dosing
- This suggests weekly PTH favours cortical structure which is what we want when the goal is visible bone growth
PubMed link


From what I gather Daily PTH tends to target trabecular bone (spine, vertebrae), while weekly PTH appears to favour cortical bone modelling.

Cortical gains could theoretically contribute to bone thickness/projection in areas like the mandible/chin/zygomatics. Let me know your thoughts.

@Zagro @Bitchwhipper2​

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Is this true ?

 

[CertifiedGoy]

Is this true ?

Not sure tbh, would be good if it was as you'd spend less on needles and have less injections while getting better results

 

[bunny8]

Greetings niggas, I found a study suggesting weekly teriparatide dosing may preferentially increase cortical bone more than the usual daily injections.

TERABIT Trial – QCT Analysis

-Compared daily (20 µg) vs weekly (56.5 µg) teriparatide
-Weekly dosing increased cortical volumetric BMD and cortical bone volume more than daily dosing
- This suggests weekly PTH favours cortical structure which is what we want when the goal is visible bone growth
PubMed link


From what I gather Daily PTH tends to target trabecular bone (spine, vertebrae), while weekly PTH appears to favour cortical bone modelling.

Cortical gains could theoretically contribute to bone thickness/projection in areas like the mandible/chin/zygomatics. Let me know your thoughts.

@Zagro @Bitchwhipper2​

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thank you

 

[Zagro]

Greetings niggas, I found a study suggesting weekly teriparatide dosing may preferentially increase cortical bone more than the usual daily injections.

TERABIT Trial – QCT Analysis

-Compared daily (20 µg) vs weekly (56.5 µg) teriparatide
-Weekly dosing increased cortical volumetric BMD and cortical bone volume more than daily dosing
- This suggests weekly PTH favours cortical structure which is what we want when the goal is visible bone growth
PubMed link


From what I gather Daily PTH tends to target trabecular bone (spine, vertebrae), while weekly PTH appears to favour cortical bone modelling.

Cortical gains could theoretically contribute to bone thickness/projection in areas like the mandible/chin/zygomatics. Let me know your thoughts.

@Zagro @Bitchwhipper2​

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Very interesting but its confusing why would it be more biased to cortical bone when dosed weekly need to look into it further

 

[Rayryan]

Greetings niggas, I found a study suggesting weekly teriparatide dosing may preferentially increase cortical bone more than the usual daily injections.

TERABIT Trial – QCT Analysis

-Compared daily (20 µg) vs weekly (56.5 µg) teriparatide
-Weekly dosing increased cortical volumetric BMD and cortical bone volume more than daily dosing
- This suggests weekly PTH favours cortical structure which is what we want when the goal is visible bone growth
PubMed link


From what I gather Daily PTH tends to target trabecular bone (spine, vertebrae), while weekly PTH appears to favour cortical bone modelling.

Cortical gains could theoretically contribute to bone thickness/projection in areas like the mandible/chin/zygomatics. Let me know your thoughts.

@Zagro @Bitchwhipper2​

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is it true that the dose we take is underdoes? and in order to make it effective we have to mega dose it?

 

[CertifiedGoy]

Very interesting but its confusing why would it be more biased to cortical bone when dosed weekly need to look into it further

I believe it’s because weekly dose gives high amplitude, intermittent PTH signals that downregulate sclerostin expression in osteocytes and strongly activate periosteal osteoblasts which promotes modelling cortical bone formation whereas the daily dosing produces sustained, smaller cAMP/PKA signaling that predominantly stimulates remodelling in trabecular bone where surface area and turnover rates are higher

 

[CertifiedGoy]

is it true that the dose we take is underdoes? and in order to make it effective we have to mega dose it?

Im not sure tbh

 

[wannabemogger]

Greetings niggas, I found a study suggesting weekly teriparatide dosing may preferentially increase cortical bone more than the usual daily injections.

TERABIT Trial – QCT Analysis

-Compared daily (20 µg) vs weekly (56.5 µg) teriparatide
-Weekly dosing increased cortical volumetric BMD and cortical bone volume more than daily dosing
- This suggests weekly PTH favours cortical structure which is what we want when the goal is visible bone growth
PubMed link


From what I gather Daily PTH tends to target trabecular bone (spine, vertebrae), while weekly PTH appears to favour cortical bone modelling.

Cortical gains could theoretically contribute to bone thickness/projection in areas like the mandible/chin/zygomatics. Let me know your thoughts.

@Zagro @Bitchwhipper2​

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who gives a fuck, pth analogs are useless

 

[CertifiedGoy]

who gives a fuck, pth analogs are useless

Not when paired with gh and androgens

 

[Zagro]

Not when paired with gh and androgens

Don't interact with him he's superior in chromosome count compared to us

 

[wannabemogger]

Not when paired with gh and androgens

take your fucking teriparatide and tell me if anything changes apart from your dexa scan you stupid nigga

 

[wannabemogger]

Don't interact with him he's superior in chromosome count compared to us

u gotta be larping

 

[Zagro]

u gotta be larping

Yeah bro I'm larping

Specify what it is that I larp please

 

[CertifiedGoy]

take your fucking teriparatide and tell me if anything changes apart from your dexa scan you stupid nigga

Keep ldaring you boneless freak while some us actually try shit cause we arent pussy

 

[wannabemogger]

Keep ldaring you boneless freak while some us actually try shit cause we arent pussy

the boneless one is you, are you sped or smth
youre larping on clinical drugs that only increase cortical density thinking youre going to ascend, hang yourself

 

[wannabemogger]

Yeah bro I'm larping

Specify what it is that I larp please

so you are retarded or no?

 

[Zagro]

so you are retarded or no?

@CertifiedGoy look here you can obviously see his superiority in chromosome count, right after i call him a retard he goes on to call me a retard, this is a common thing called projecting.

His reply to my post doesn’t even make sense in the slightest and he doesn’t even know what larp means

 

[Noesis]

Abalo mogs

 

[CertifiedGoy]

the boneless one is you, are you sped or smth
youre larping on clinical drugs that only increase cortical density thinking youre going to ascend, hang yourself

Ive got more bones than you ever will rofl. Increased cortical density can be visible you ape, and the effects will be amplified when paired with other compounds

 

[wannabemogger]

@CertifiedGoy look here you can obviously see his superiority in chromosome count, right after i call him a retard he goes on to call me a retard, this is a common thing called projecting.

His reply to my post doesn’t even make sense in the slightest and he doesn’t even know what larp means

no do you think pth analogs are some miracle ascension?

 

[wannabemogger]

Ive got more bones than you ever will rofl. Increased cortical density can be visible you ape, and the effects will be amplified when paired with other compounds

tiktok knowledge
show me a picture of u pinning it, retarded subhuman

 

[CertifiedGoy]

no do you think pth analogs are some miracle ascension?

He hasn't said that once you muppet

 

[CertifiedGoy]

tiktok knowledge
show me a picture of u pinning it, retarded subhuman

Can't even disprove it so you just resort to "tiktok knowledge" which is expected with a low iq inbred like you

 

[wannabemogger]

He hasn't said that once you muppet

he clearly thinks it you muppet

 

[Zagro]

no do you think pth analogs are some miracle ascension?

You fucking imbecile theres nothing that will magically work, do you think looksmaxxing is a one step thing? Do you become chad after dyeing your eyebrows? What is this retarded reasoning. You’re a fucking useless subhuman being you fucking iqlet only thing you can fucking say is surgery but it seems like you aren’t aware of the prices nor the legal requirements, as expected as you have literally zero knowledge regarding any fucking topic.

“Yeah bro i wont lean down it wont make me chad anyways.”, “yeah no i wont whiten my teeth it wont make me chad anyways.” This is the logic you use, there isn’t any fucking magical method you fucktard its all little steps that contribute to your looks and this is a compound which is an add-on that synergises well.

“No bro tiktok knowledge ahaha do you think this will make you chad more bone mass haha peptides cope, just do surgery bro LL bro implants ahahah”

 

[wannabemogger]

Can't even disprove it so you just resort to "tiktok knowledge" which is expected with a low iq inbred like you

you clearly are someone with subhuman ratios, mistreated throughout life and youre desperately hoping you just discovered the godsend of bone drugs
unfortunately cortical density increase =/= new bone growth -> no visisble change at all
is this true or not, i sometimes hear out retarded people

 

[wannabemogger]

You fucking imbecile theres nothing that will magically work, do you think looksmaxxing is a one step thing? Do you become chad after dyeing your eyebrows? What is this retarded reasoning. You’re a fucking useless subhuman being you fucking iqlet only thing you can fucking say is surgery but it seems like you aren’t aware of the prices nor the legal requirements, as expected as you have literally zero knowledge regarding any fucking topic.

“Yeah bro i wont lean down it wont make me chad anyways.”, “yeah no i wont whiten my teeth it wont make me chad anyways.” This is the logic you use, there isn’t any fucking magical method you fucktard its all little steps that contribute to your looks and this is a compound which is an add-on that synergises well.

“No bro tiktok knowledge ahaha do you think this will make you chad more bone mass haha peptides cope, just do surgery bro LL bro implants ahahah”

DNR pth analogs dont do anything
send me a pic of you using them

 

[CertifiedGoy]

subhuman ratios, mistreated throughout life and youre desperately hoping you just discovered the godsend of bone drugs

74% frontal harmony. Wrong. Nobody said that you twat its been talked about lots on here and its just a useful add on to stacks

cortical density increase =/= new bone growth

What do you think cortical is you faggot

 

[Zagro]

74% frontal harmony. Wrong. Nobody said that you twat its been talked about lots on here and its just a useful add on to stacks

What do you think cortical is you faggot

Put him on ignore and move on bro honestly not worth your time

 

[wannabemogger]

74% frontal harmony. Wrong. Nobody said that you twat its been talked about lots on here and its just a useful add on to stacks

What do you think cortical is you faggot

arent you an incel
anyways lemme say it one more time for your gaped asshole, cortical density =/= new bone
got that sweetheart? is it processing now?

 

[wannabemogger]

Put him on ignore and move on bro honestly not worth your time

yh ignore me because you cant answer back, you larp larp larp about how pth analogs are so great when you dont know what the fuck youre spewing from that dicksucking mouthhole

 

[CertifiedGoy]

ortical density =/= new bone

Which is why you pair it with gh and androgens bud

 

[Zagro]

yh ignore me because you cant answer back, you larp larp larp about how pth analogs are so great when you dont know what the fuck youre spewing from that dicksucking mouthhole

DNR

 

[wannabemogger]

DNR

View attachment 4356083

is that applejuice or piss maybe?

 

[wannabemogger]

Which is why you pair it with gh and androgens bud

"just close your growth plates theory brootal"
are you on medication when you speak to me?

 

[CertifiedGoy]

"just close your growth plates theory brootal"
are you on medication when you speak to me?

Ever heard of an ai

 

[Zagro]

Ever heard of an ai

He doesn’t know how premature epiphyseal ossification occurs

is that applejuice or piss maybe?

Trenbolone enanthate, but i understand it may be confusing for your brain the same size to that of an hummingbird’s brain

 

[wannabemogger]

He doesn’t know how premature epiphyseal ossification occurs


Trenbolone enanthate, but i understand it may be confusing for your brain the same size to that of an hummingbird’s brain

this nd nigga just heard of estrogen for the first time and got giddy, aw look at you my poor baby faggot
also did u piss in it?

 

[Zagro]

this nd nigga just heard of estrogen for the first time and got giddy, aw look at you my poor baby faggot
also did u piss in it?

This dude gotta be trolling bro ahhahaha

 

[wannabemogger]

This dude gotta be trolling bro ahhahaha

 

[wannabemogger]

Ever heard of an ai

yh you just proved to me that youre some sort of spastic