Why doesn’t anyone on here ever talk about myostatin inhibitors?

[jallrd]

I’m looking into travagomab and goretusmab but there’s no info on either on here. Hopefully this will spark interest and discussion

 

[slaters]

Because they’re trash

 

[jallrd]

Because they’re trash

Why are they trash?

 

[axm]

Why are they trash?

Interim Results from Ongoing Phase 2 COURAGE Trial Confirm Potential to Improve the Quality of Semaglutide (GLP-1 receptor agonist)-induced Weight Loss by Preserving Lean Mass | Regeneron Pharmaceuticals Inc.

Trial demonstrated that approximately 35% of semaglutide-induced weight loss was due to loss of lean mass Combining semaglutide with muscle-preserving antibodies protected lean mass – sparing approximately 50%-80% of the lean mass lost with semaglutide alone – while also increasing loss of fat mass

newsroom.regeneron.com

Human trials weren’t as promising as the primate trials. Helped attenuate muscle loss from glp-1 RA’s but nothing crazy like full blown recomp. Basically same results as like ostarine.