Why HGH is cope and will NOT work for you!!!! (HGH USERS GTFIH!!!)

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

 

[anphamer]

I owe you a french kiss

 

[onfoenem]

dnr fag

 

[greedpsl]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

bump

 

[ihatemySOST]

Kill ur self fucking faggot

 

[Ahmed88]

Kill ur self fucking faggot

Now niggas act when they can't sell little kids their overpriced hgh

 

[Ahmed88]

Bump

 

[vernier]

Water but most of the greys are retarded so this needs to be seen

 

[ThanksForTheHGHMom]

Yes, HGH will not make you taller than you were supposed to be unless you have an issue producing it naturally. Great post

 

[Looker14y]

but for bone density and "size" it would work no or not even, maybe i miss read only skimmed through
but would it work with romo for example, inhibiting sclerostin whichi inhibits bone formation?
genuine question

 

[mohi_100]

This deserves a bump

 

[Looker14y]

But yeah newgens and gymcells should def see this mega bump
you should specifically say final height in the title tho not just hgh is cope

 

[L1mbal]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

So how do i increase my height bro

 

[Zagro]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

Yess once another retard i swear to god threads like this get made weekly

 

[Zagro]

This deserves a bump

And retards like him support this

 

[Ahmed88]

Yess once another retard i swear to god threads like this get made weekly

Still didn't reply to me in our last argument and just left, retard if you cant give evidence of your claims dont reply faggot just keep injecting hgh and become a 5'4 manlet with edema

 

[mohi_100]

And retards like him support this

Buzzword unless u prove that hgh can increase final height in non deficient children

 

[Ahmed88]

Buzzword unless u can prove that hgh can increase final height in non deficient children

He couldn't, i asked him multiple times to back up his claims, dont even bother arguing with this fag, all he does is throw buzzwords around like a turkish femboy i bet hes one of those retarded nigtok peptides sellers selling ratpiss to little kids

 

[Zagro]

Still didn't reply to me in our last argument and just left, retard if you cant give evidence of your claims dont reply faggot just keep injecting hgh and become a 5'4 manlet with edema

I answered and you tweaked out like a retard “faggot, DNR, kys, claviular” etc there wasn’t even a debate as you didn’t counter-argument, you ironically started to contradict your own claims after my replies

Also you were the one making the claims without evidence and i was the one teaching you how acromegalic niggas cant compare to an healthy adolescent

Stop using gpt aswell

Buzzword unless u prove that hgh can increase final height in non deficient children

Learn the human body instead of using AI to look into what a drug does.

Mr. Sodium alendronate for bone growth

If you really want to know check the last 15 ish threads I’ve replied to which were identical to this one

Post in thread 'HGH Will NOT Make You Taller.'
https://looksmax.org/threads/hgh-will-not-make-you-taller.1726011/post-24471932

This is a weekly occurrence

 

[Ahmed88]

I answered and you tweaked out like a retard “faggot, DNR, kys, claviular” etc there wasn’t even a debate as you didn’t counter-argument, you ironically started to contradict your own claims after my replies

Also you were the one making the claims without evidence and i was the one teaching you how acromegalic niggas cant compare to an healthy adolescent

Stop using gpt aswell

Holy shit guys dont listen to this retard all he did was keep on saying the same argument on why if it works for ISS it works for normal people ,,A decent chunk of them actually don't have any reason behind their height they're just short, but guess what they still grow'' holy shit nigga you are NOT iss i explained why it works for them and NOT YOU

 

[Ahmed88]

So how do i increase my height bro

genuine question

if anyone wants to ask questions just pm me

 

[Zagro]

Holy shit guys dont listen to this retard all he did was keep on saying the same argument on why if it works for ISS it works for normal people ,,A decent chunk of them actually don't have any reason behind their height they're just short, but guess what they still grow'' holy shit nigga you are NOT iss i explained why it works for them and NOT YOU

Are you a clinically diagnosed retard?

ISS is very much comparable to healthy kids, as most of them are literal healthy kids lmao

 

[mohi_100]

I answered and you tweaked out like a retard “faggot, DNR, kys, claviular” etc there wasn’t even a debate as you didn’t counter-argument, you ironically started to contradict your own claims after my replies

Also you were the one making the claims without evidence and i was the one teaching you how acromegalic niggas cant compare to an healthy adolescent

Stop using gpt aswell


Learn the human body instead of using AI to look into what a drug does.

Mr. Sodium alendronate for bone growth

If you really want to know check the last 15 ish threads I’ve replied to which were identical to this one

Post in thread 'HGH Will NOT Make You Taller.'
https://looksmax.org/threads/hgh-will-not-make-you-taller.1726011/post-24471932

This is a weekly occurrence

Alright, im linking ur post here so others can see it too. In the study you referenced, the treated group surpassed their genetic target height by +0.29 sd (which is like about less than an inch here)

https://looksmax.org/threads/hgh-will-not-make-you-taller.1726011/post-24473306

By the way, i was only arguing for alendronate in that context because it's approved for osteoporosis

 

[Ahmed88]

Are you a clinically diagnosed retard?

ISS is very much comparable to healthy kids, as most of them are literal healthy kids lmao

Just read my fucking explanation nigga it takes one search to find out iss children arent short cause of genetics, yes they are healthy medically because there is no explanation for their short stature (so basically they dont know whats wrong) stop saying the same thing over and over again

 

[susisesi]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

literally impacted my frame in under 1 month.

 

[Looker14y]

literally impacted my frame in under 1 month.

muscle and water weight + he said heigth im 90% sure it impacts density and size
correct me if im wrong

 

[Ahmed88]

literally impacted my frame in under 1 month.

Read why people think it works it grows ur bones faster for a short time period which makes it seem like its working and also other factors

 

[Zagro]

Just read my fucking explanation nigga it takes one search to find out iss children arent short cause of genetics stop saying the same thing over and over again

Wow you really are a retard innit

Read why people think it works it grows ur bones faster for a short time period which makes it seem like its working and also other factors

Nigga made the thread his signature this is not life-changing information jfl let me debunk this in a thread soon

 

[Noahlooksmaxx]

Theoretical increased cancer risk due to chronic IGF‑1 stimulation

Our results do not generally support a carcinogenic effect of r-hGH only realy true if previous cancer problems existed btw but: bone cancer, bladder cancer, and HL risks

 

[Ahmed88]

Our results do not generally support a carcinogenic effect of r-hGH only realy true if previous cancer problems existed btw but: bone cancer, bladder cancer, and HL risks

i am emphasizing the biological mechanism rather then epidemiological evidence

 

[Ahmed88]

Wow you really are a retard innit

,,muhhh retard iss are normal trust me'' keep saying retarded faggot shit like that u genuinely gotta be trolling ill wait till you bring actual studies

 

[Noahlooksmaxx]

,,muhhh retard iss are normal trust me'' keep saying retarded faggot shit like that u genuinely gotta be trolling ill wait till you bring actual studies

well every normal human beeing knows that u cant grow past genetic max tho right

 

[Ergogenic]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

Growth hormone certainly will increase final height growth if the doses are high enough. Look at the case of Robert Wadlow.

You could just inject 10 to 30 international units of growth hormone per day to see noticeable results. This only is a good idea if you have enough money. 1 international unit of growth hormone is 0.33 milligrams. 1 milligram of growth hormone is equal to 3 international units.

There is also no way to know if you have growth hormone deficiency for any reason until you get tested. Any child and teenager that is not sleeping enough per day (8 hours) is certainly underproducing growth hormone, and that will result in earlier maturation of the epiphyseal plates, so it will not be a bad idea to take advantage of this.

 

[Ahmed88]

Growth hormone certainly will increase final height growth if the doses are high enough. Look at the case of Robert Wadlow.

You could just inject 10 to 30 international units of growth hormone per day to see noticeable results. This only is a good idea if you have enough money. 1 international unit of growth hormone is 0.33 milligrams. 1 milligram of growth hormone is equal to 3 international units.

There is also no way to know if you have growth hormone deficiency for any reason until you get tested. Any child and teenager that is not sleeping enough per day (8 hours) is certainly underproducing growth hormone, and that will result in earlier maturation of the epiphyseal plates, so it will not be a bad idea to take advantage of this.

No

 

[Ahmed88]

well every normal human beeing knows that u cant grow past genetic max tho right

zagro doesnt

 

[nakus]

smart post from title

 

[Ergogenic]

Ahhh yes lets give ourselfs giganstism and die at 20 theory

Not if you discontinue using it at your desired height. There is no good reason to grow above 190 centimetres. There is an ideal range of height, and that is probably between 175 to 190 centimetres. Above 190 will be detrimental to quality of life.

I am 173 centimetres at 20 years old now. I likely could have grown to 175 centimetres and beyond if I slept enough. I only averaged 6 hours of sleep per day during puberty. Some days less hours than 6.

I had no knowledge on growth hormone or aromatase inhibitors back then either.

 

[Ahmed88]

Not if you discontinue using it at your desired height. There is no good reason to grow above 190 centimetres. There is an ideal range of height, and that is probably between 175 to 190 centimetres. Above 190 will be detrimental to quality of life.

I am 173 centimetres at 20 years old now. I likely could have grown to 175 centimetres and beyond if I slept enough. I only averaged 6 hours of sleep per day during puberty. Some days less hours than 6.

I had no knowledge on growth hormone or aromatase inhibitors back then either.

Read the part, with feedback system everything is there including

 

[Ergogenic]

Read the part, with feedback system everything is there including

I already had. I actively read through your whole post.

I am not a scientist, so I have no studies or counter points, but I do care about the difference between what is written on paper, and what happens in the real world.

Estrogen is mainly responsible for epiphyseal plates to fuse. This is why growth hormone is to be used with aromatase inhibitors unless estrogen is already naturally low. The point is to keep estrogen low but not crash it because estrogen is also essential for good bone and cardiovascular health.

How could the case of Robert Wadlow or any other individual with gigantism be possible according to your post?

 

[motionmantris]

I answered and you tweaked out like a retard “faggot, DNR, kys, claviular” etc there wasn’t even a debate as you didn’t counter-argument, you ironically started to contradict your own claims after my replies

Also you were the one making the claims without evidence and i was the one teaching you how acromegalic niggas cant compare to an healthy adolescent

Stop using gpt aswell


Learn the human body instead of using AI to look into what a drug does.

Mr. Sodium alendronate for bone growth

If you really want to know check the last 15 ish threads I’ve replied to which were identical to this one

Post in thread 'HGH Will NOT Make You Taller.'
https://looksmax.org/threads/hgh-will-not-make-you-taller.1726011/post-24471932

This is a weekly occurrence

can u please lmk what u think about hgh for height and test for bones and please give sources

 

[fractual]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

Genes determine the number of chondrocytes in the growth plates, how fast they divide, how long plates stay open, sensitivity to gh, and timing of puberty. So that means a maximum height is genetically limited.
You can still absolutely optimize conditions so those condrocytes divide longer, more efficiently, and delay exhaustion and growth plate closure. Things that affect these condrocytes are gh and igf-1 levels, estrogen exposure, nutrition,sleep and overall health.
When people talk about growing taller with hgh here some retards think blastin that shit while being like 5’6 at 16 will magically growth them to 6ft, which is not what happens. The studies you cited weren’t even using enough gh and likely wasn’t implementing aromaste inhibitors which is needed to keep the growth plates open while you actually grow faster. Reasonably there’s a bone age limit where no sort of peptide will seriously help with height but it’s not impossible to say with a good hgh+ai cycle you can’t squeeze in some extra cm. Like let’s say you start gh at 15 sharp and you’re 5’7, you’ll probably be 5’9-5’11 no intervention but gh can realistically push that up to 5’10-6’1. Of course this is assuming optimal conditions and blood tests. Most dumbasses here won’t reap any benefit from pinning hgh. A real cycle that would help would be very expensive for the avg highschooler

Mirin thread tho

 

[Ahmed88]

I already had. I actively read through your whole post.

I am not a scientist, so I have no studies or counter points, but I do care about the difference between what is written on paper, and what happens in the real world.

Estrogen is mainly responsible for epiphyseal plates to fuse. This is why growth hormone is to be used with aromatase inhibitors unless estrogen is already naturally low. The point is to keep estrogen low but not crash it because estrogen is also essential for good bone and cardiovascular health.

How could the case of Robert Wadlow or any other individual with gigantism be possible according to your post?

Robert wadlow had a tumour, we do not, his tumour supressed his natural feedback system extremely, exogenous hgh does not, ais do not reliably increase your height there are multiple threads on this, all my claims are backed by studies what most people say here is a theory on paper with no evidence

 

[Ahmed88]

Genes determine the number of chondrocytes in the growth plates, how fast they divide, how long plates stay open, sensitivity to gh, and timing of puberty. So that means a maximum height is genetically limited.
You can still absolutely optimize conditions so those condrocytes divide longer, more efficiently, and delay exhaustion and growth plate closure. Things that affect these condrocytes are gh and igf-1 levels, estrogen exposure, nutrition,sleep and overall health.
When people talk about growing taller with hgh here some retards think blastin that shit while being like 5’6 at 16 will magically growth them to 6ft, which is not what happens. The studies you cited weren’t even using enough gh and likely wasn’t implementing aromaste inhibitors which is needed to keep the growth plates open while you actually grow faster. Reasonably there’s a bone age limit where no sort of peptide will seriously help with height but it’s not impossible to say with a good hgh+ai cycle you can’t squeeze in some extra cm. Like let’s say you start gh at 15 sharp and you’re 5’7, you’ll probably be 5’9-5’11 no intervention but gh can realistically push that up to 5’10-6’1. Of course this is assuming optimal conditions and blood tests. Most dumbasses here won’t reap any benefit from pinning hgh. A real cycle that would help would be very expensive for the avg highschooler

Mirin thread tho

Thanks, Surpassing your genetic limit is biologically impossible no amount of hgh and ai can surpass it andwe need e2 for growth since it enhances hgh and igf1 signaling in growth plates and supports chondrocyte , supressing e2 would likely have negative effects on your health and height

 

[motionmantris]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

rep ratio checks out

 

[Ahmed88]

can u please lmk what u think about hgh for height and test for bones and please give sources

Massai jumps and sprints for hgh and royal jelly for test

 

[fractual]

Thanks, Surpassing your genetic limit is biologically impossible no amount of hgh and ai can surpass it andwe need e2 for growth since it enhances hgh and igf1 signaling in growth plates and supports chondrocyte , supressing e2 would likely have negative effects on your health and height

Completely agree. More manlet retards who are already expected to hit MPH need to see this before pining 10 iu and doing 12.5 mg aromasin ed

 

[TheOsei]

Why HGH does NOT work for healthy normal children with PROOF

the study you linked is only using 0.5iu/kg A WEEK no shit that won't do anything. natural levels are around a median of 5.6 plus u gotta add 17% iu for bioavailability subq to match relative to natural production. gotta be doing at least 7iu to see anything

 

[forwardridge]

 

[Ahmed88]

the study you linked is only using 0.5iu/kg A WEEK no shit that won't do anything. natural levels are around a median of 5.6 plus u gotta add 17% iu for bioavailability subq to match relative to natural production. gotta be doing at least 7iu to see anything

Thats 6ius/day for a 80kg and they also used 1iu/kg a week which would be 12iu/day which is double or 3x more, what some people inject. Both of them did not show an increase in adult height

 

[growth_forward7777]

Thats 6ius/day for a 80kg and they also used 1iu/kg a week which would be 12iu/day which is double or 3x more, what some people inject. Both of them did not show an increase in ad

Thats 6ius/day for a 80kg and they also used 1iu/kg a week which would be 12iu/day which is double or 3x more, what some people inject. Both of them did not show an increase

Thats 6ius/day for a 80kg and they also used 1iu/kg a week which would be 12iu/day which is double or 3x more, what some people inject. Both of them did not show an increase in adult height

so are u saying hgh won’t make u taller if ur growth plates are open, or that it can’t increase ur genetic adult height?