A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.
It won’t.
Why?
Let’s get into this
1. How Growth Hormone Actually Works
2. What the Studies ACTUALLY Show
3. Why HGH does NOT work for healthy normal children with PROOF
4. Why people think it works!!!!!!
5. What you actually get and are paying for: Side Effects
6. Summary
It won’t.
Why?
Let’s get into this
1. How Growth Hormone Actually Works
Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases
Its main job?
Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.
Its main job?
Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.
2. What the Studies ACTUALLY Show
People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.
Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:
VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.
Some other studies explore ISS (Idiopathic Short Stature):
B-B-But ISS Children Grew Taller why can’t i?
Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)
Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.
Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:
- Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
- Use of growth hormone in children with GHD
- Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
- National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
- Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
- Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
- Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency
VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.
Some other studies explore ISS (Idiopathic Short Stature):
- Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
- THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
- Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
- Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center
B-B-But ISS Children Grew Taller why can’t i?
Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)
Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.
3. Why HGH does NOT work for healthy normal children with PROOF
For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:
Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed
No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC
https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X
No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed
Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.
Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.
- GH does not create new growth potential.
The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits. - GH cannot override genetic determinants of stature.
Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains. - Endocrine feedback loops limit excessive growth signaling.
The GH–IGF-1 axis is tightly regulated:- Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
- Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
- Physiologic ceiling effect.
In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration
Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed
No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC
https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X
No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed
Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.
Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.
4. Why people think it works!!!!!!
This is where most people get fooled and start to think it’s working.
HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.
HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.
5. What you actually get and are paying for: Side Effects
Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:
- Insulin resistance
- Increased risk of type 2 diabetes
- Fluid retention and edema
- Joint pain
- Carpal tunnel syndrome
- Hip growth plate injury
- Benign intracranial hypertension (severe headaches and vision changes)
- Abnormal IGF‑1 elevations
- Theoretical increased cancer risk due to chronic IGF‑1 stimulation
6. Summary
HGH only works in:
HGH does NOT:
The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.
Biology does not care about your retarded cope.
- Documented GH deficiency
- Select ISS cases
HGH does NOT:
- Make normal kids taller than their genetics allow
- Extend growth plates
- Increase final adult height
- Create height out of nowhere
The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.
Biology does not care about your retarded cope.
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