DNRerard
Oldfag
- Joined
- Jan 28, 2026
- Posts
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People who promote osteoporosis drugs are ChatGPT warriors. They know nothing about how or why osteoporosis is relevant. romosozumabs effects are dominated by endosteal modelling/remodelling, not sustained periosteal expansion. all these so called “bone mass drugs” are the same way. this is due to periosteal expansion MAINLY BEING EPIGENETIC and there being no way of specifically targeting the areas you want. no, you cannot locally inject as you would need a crazy low half life and a crazy high effect, that doesn’t even consider that periosteal cells are very slow. I could list 50 other reasons why this take makes 0 sense but this alone is enough
