0.25 fin or topical fin or topical dut

[new psl]

I don't wanna block systematic dht and affect serum dht , what would be better?

 

[Ogionth]

I don't wanna block systematic dht and affect serum dht , what would be better?

Each of them will reduce your serum dht, no matter what.

0.25% topical fin will lead to a reduction of 34.5% in Serum DHT (55.6% for oral).

Scalp DHT will be lowered by abt 50% for topical which is quite similar to oral.

 

[Ogionth]

Each of them will reduce your serum dht, no matter what.

0.25% topical fin will lead to a reduction of 34.5% in Serum DHT (55.6% for oral).

Scalp DHT will be lowered by abt 50% for topical which is quite similar to oral.

Read these studies for a detailed explanation.


First. Lee SW, et al. "The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis." Clin Interv Aging.

2019




Second. Caserini M, et al. "Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone levels in subjects with androgenetic alopecia." Br J Dermatol. 2016.



Third. Casiraghi A, et al. "Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a randomized, controlled, phase III study." J Eur Acad Dermatol Venereol. 2021.


4th. Kaufman KD, et al. "The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia." J Am Acad Dermatol. 1999


5. Shapiro J, et al. "Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Treatment." Dermatol Ther (Heidelb). 2023