ndos
6'4.5'',wide frame,acnecel,here to looksmax
- Joined
- Sep 14, 2022
- Posts
- 737
- Reputation
- 488
Oral isotretinoin in photoaging: objective histological evidence of efficacy and durability
The off-label use of oral isotretinoin in photoaging is a therapeutic tool that has been used by dermatologists. There are few studies to corroborate its effectiveness and durability.To assess, both clinically and histologically, the changes caused by ...
www.ncbi.nlm.nih.gov
"We observed anincrease in collagen density, from 51.2% to 57.4%, (p=0.004). At the end of the12-week follow-up period, this density decreased to 54.7% (p=0.050). There was anincrease in the density of elastic fibers, from 26.5% to 31.3%, (p=0.02), whichhad dropped to 27.5% at the end of the 12-week follow-up period."