SECTION 1: ACCUTANE/ISOTRETINOIN
Isotretinoin is a vitamin A derivative oral retinoid used to treat severe acne. It works by reducing sebum (oil) production at the source. It is the most effective treatment for acne, no amount of skincare products moisturisers, cleansers, topical retinoids will give you the same the results.
Isotretinoin works systemically meaning it affects the entire body internally through the bloodstream unlike topical retinoids that work externally.
It reduces sebaceous gland size,sebum production, inflammation,normalises skin cell turnover, prevents new clogged pores and is FDA approved.
SECTION 2: Dosage
When taking isotretinoin there is something called a cumulative dose(total mg), What that means is your course should consist of a certain amount of mg depending on your weight. How do you calculate this ? You should be taking 120 to 150 mg per kilogram so you multiply the amount of kilograms you weigh by 120-150mg so let’s say you weight 60kg.
60x120= 7200 or 60x150= 9000 this is your cumulative dose.
Now how you reach that dose also depends on your weight you should take 0.5 to 1mg per kg a day we will use the same weight here so lets say:
0.5 x60=30mg or 1x60=60mg
This is obvious but keep in mind the higher your daily mg the more side effects you will get but the faster you will reach your cumulative dose same vice versa. What matters most is consistency and reaching your cumulative dose.
SECTION 3: Side effects, Solutions
Your skin becomes more sensitive so you’re gonna wanna use a spf50+ sunscreen and one that protects against both UVB and UVA rays.
You will have dry lips so make sure you have chapstick and aquaphor on you 24/7.
Some people experience nosebleeds, for this use a saline spray, spray it 2-3 times for each nostril before sleep.
For dry skin any moisturiser should be fine but preferably a thick one.
Joint pain, this one is rare but if it does happen reduce joint stress, hydrate enough, take omega 3s like fish oil, and if that doesn’t work reduce the dose slightly.
SECTION 4: How to get Isotretinoin? (two ways)
You can get Isotretinoin prescribed by a dermatologist. Just tell them you tried every single skincare product and topical retinoid but nothing seemed to work.
You will need to do monthly blood tests for your liver though. It shouldn’t be too hard to get it prescribed. Switch dermatologists if they prescribe you more topical shit.
You can also get Isotretinoin illegally through online pharmacies on Indiamart or search on Reddit or TikTok people will give you a phone number of someone who sells it.
Before buying make sure the person selling is trustworthy, ask for pictures, vouches etc.
It’s much cheaper without the blood tests but do it at your own risk. Prices range around 50-200 dollars for a full course.
Conclusion
Isotretinoin is the best treatment for acne out there and will clear 60-80% of people long term. Most isotretinoin brands are fat soluble so make sure your meal contains fat, and then after the meal take your daily dose.Most importantly don’t drink alcohol while on isotretinoin and don’t get pregnant.
Isotretinoin is a vitamin A derivative oral retinoid used to treat severe acne. It works by reducing sebum (oil) production at the source. It is the most effective treatment for acne, no amount of skincare products moisturisers, cleansers, topical retinoids will give you the same the results.
Isotretinoin works systemically meaning it affects the entire body internally through the bloodstream unlike topical retinoids that work externally.
It reduces sebaceous gland size,sebum production, inflammation,normalises skin cell turnover, prevents new clogged pores and is FDA approved.
SECTION 2: Dosage
When taking isotretinoin there is something called a cumulative dose(total mg), What that means is your course should consist of a certain amount of mg depending on your weight. How do you calculate this ? You should be taking 120 to 150 mg per kilogram so you multiply the amount of kilograms you weigh by 120-150mg so let’s say you weight 60kg.
60x120= 7200 or 60x150= 9000 this is your cumulative dose.
Now how you reach that dose also depends on your weight you should take 0.5 to 1mg per kg a day we will use the same weight here so lets say:
0.5 x60=30mg or 1x60=60mg
This is obvious but keep in mind the higher your daily mg the more side effects you will get but the faster you will reach your cumulative dose same vice versa. What matters most is consistency and reaching your cumulative dose.
SECTION 3: Side effects, Solutions
Your skin becomes more sensitive so you’re gonna wanna use a spf50+ sunscreen and one that protects against both UVB and UVA rays.
You will have dry lips so make sure you have chapstick and aquaphor on you 24/7.
Some people experience nosebleeds, for this use a saline spray, spray it 2-3 times for each nostril before sleep.
For dry skin any moisturiser should be fine but preferably a thick one.
Joint pain, this one is rare but if it does happen reduce joint stress, hydrate enough, take omega 3s like fish oil, and if that doesn’t work reduce the dose slightly.
SECTION 4: How to get Isotretinoin? (two ways)
You can get Isotretinoin prescribed by a dermatologist. Just tell them you tried every single skincare product and topical retinoid but nothing seemed to work.
You will need to do monthly blood tests for your liver though. It shouldn’t be too hard to get it prescribed. Switch dermatologists if they prescribe you more topical shit.
You can also get Isotretinoin illegally through online pharmacies on Indiamart or search on Reddit or TikTok people will give you a phone number of someone who sells it.
Before buying make sure the person selling is trustworthy, ask for pictures, vouches etc.
It’s much cheaper without the blood tests but do it at your own risk. Prices range around 50-200 dollars for a full course.
Conclusion
Isotretinoin is the best treatment for acne out there and will clear 60-80% of people long term. Most isotretinoin brands are fat soluble so make sure your meal contains fat, and then after the meal take your daily dose.Most importantly don’t drink alcohol while on isotretinoin and don’t get pregnant.
