AMA about roids and PEDs, i will answer as well as i can

nwed

nwed

dc: mvrxin
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i'm bored, ask me everything
 
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bump
 
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Is creatine safe to take at 38
 
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Is creatine safe to take at 38
lol, i know this is troll but creatine benefits are actually more mental than physical so it should be recommended to older ppl imo
 
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Can potent androgens like tren/halo stunt ur final adult height due to accelerated bone age and premature cartilage senescence? And also how to avoid gh gut on giga doses hgh
 
Can potent androgens like tren/halo stunt ur final adult height due to accelerated bone age and premature cartilage senescence? And also how to avoid gh gut on giga doses hgh
nope they dont, androgenic mediated fusion OUTSIDE of ERa signaling doesnt exist
1786539333977


looking at the ending of this study there is basically no difference in final bone lenght, and tren is also progestogenic so it upregulates ER sensitivity

on the gh gut part i dont really know, ive heard about rich piana doing some waist exercise and saying they work, many ppl do those but its very bro science and there is no evidence it works, ill link you the rich piana video



holy fucking shit i fucking love rich RIP man
 
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nope they dont, androgenic mediated fusion OUTSIDE of ERa signaling doesnt exist
View attachment 5504299

looking at the ending of this study there is basically no difference in final bone lenght, and tren is also progestogenic so it upregulates ER sensitivity

on the gh gut part i dont really know, ive heard about rich piana doing some waist exercise and saying they work, many ppl do those but its very bro science and there is no evidence it works, ill link you the rich piana video



holy fucking shit i fucking love rich RIP man

Thanks bro high effort
 
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i guess i got daddy issues and i love giving my knowledge to guys in need, makes me feel good heh
Im kinda stupid can you explain the difference between tren and test on growth plates please ? Thanns
 
Im kinda stupid can you explain the difference between tren and test on growth plates please ? Thanns
testosterone: converts via estradiol via aromatase (cyp19a1) wich binds to the ERa receptors in the growth plate
It also converts into dht via 5ar wich has benefits in bone development

Trenbolone: doesnt convert into estradiol, its progestogenic so it makes the ERa receptors more sensitive to e2 and improves igf1 mRNA local expression, wich comes with a downstream of effects on wnt/catenin sox9 and many other pathways, it directly binds to AR receptors and does not 5ar reduce
 
testosterone: converts via estradiol via aromatase (cyp19a1) wich binds to the ERa receptors in the growth plate
It also converts into dht via 5ar wich has benefits in bone development

Trenbolone: doesnt convert into estradiol, its progestogenic so it makes the ERa receptors more sensitive to e2 and improves igf1 mRNA local expression, wich comes with a downstream of effects on wnt/catenin sox9 and many other pathways, it directly binds to AR receptors and does not 5ar reduce
2 Things if I decide to take test you said that the dht has benefits on bone development but what about hair loss ?
 
2 Things if I decide to take test you said that the dht has benefits on bone development but what about hair loss ?
cope, just run kx826 and minoxidil and forget

also if you run test for dht you should run masteron alongside for shbg inhibition, also you could look into using dht no ester (esterified dht does not exist) for a 5ar loop, basically more dht, proviron also works
 

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