Anyone ever experiment with Rosiglitazone?

Shirobon

Shirobon

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Looking into formulating my own topical Rosiglitazone for adipogenesis, found raw powder and looking for sources of DMSO and possibly Propylene Glycol, just curious if anyone else has done this before

tired of paying money for voluifine :forcedsmile:
 
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india my friend
 
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ye not worried about the solvents just curious if anyone else has done this before
look on reddit, people be doing all sorts there
 
look on reddit, people be doing all sorts there
not a whole lot on Rosiglitazone mostly on those of the same family but only taken orally which isnt smart, its mostly just investigational studies on pubmed but the findings are pretty lit and im not trying to wait 3 years for a definitive answer:feelswhat:
 
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Looking into formulating my own topical Rosiglitazone for adipogenesis, found raw powder and looking for sources of DMSO and possibly Propylene Glycol, just curious if anyone else has done this before

tired of paying money for voluifine :forcedsmile:
Nigha this is the stupidest shit ive ever heard. For what could you even be using Rosihlitazone. Isn't it a diabetes dug? How tf does this correlate to volufiline when topical absorbtion also means systemic?
 
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Nigha this is the stupidest shit ive ever heard. For what could you even be using Rosihlitazone. Isn't it a diabetes dug? How tf does this correlate to volufiline when topical absorbtion also means systemic?
Rosiglitazone in trials has shown to act as a PPARγ agonist, used in treatment for fibrosis and Lipodystrophy caused by radiation and other things topical Rosiglitazone doesn't go systemic:Comfy:
 
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Rosiglitazone in trials has shown to act as a PPARγ agonist, used in treatment for fibrosis and Lipodystrophy caused my radiation and other things topical Rosiglitazone doesn't go systemic:Comfy:
But you wanted to use DMSO right? Goes systemic really easily. Its only ever been studied in animal studies (for your case)
 
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But you wanted to use DMSO right? Goes systemic really easily. Its only ever been studied in animal studies (for your case)
Rosiglitazone isn't water soluble so things like ethanol, DMSO, and Propylene Glycol work. My first choice was DMSO because it penetrates the stratum corneum quickly and does reach quite deep which is likely needed to achieve true adipogenesis, this was something i mostly thought of today so I'm still looking into things but it seems promising. :feelsokman:
 
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Rosiglitazone isn't water soluble so things like ethanol, DMSO, and Propylene Glycol work. My first choice was DMSO because it penetrates the stratum corneum quickly and does reach quite deep which is likely needed to achieve true adipogenesis, this was something i mostly thought of today so I'm still looking into things but it seems promising. :feelsokman:
A meaningful amount will still get into your bloodstream tho.
 
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A meaningful amount will still get into your bloodstream tho.
definitely possible that a small amount will, but Rosiglitazone and those of it's family are highly lipid drawn so once it passes the stratum corneum and reaches the fat layer it stays there, the DMSO will go systemic but it usually leaves the body quickly
 
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definitely possible that a small amount will, but Rosiglitazone and those of it's family are highly lipid drawn so once it passes the stratum corneum and reaches the fat layer it stays there, the DMSO will go systemic but it usually leaves the body quickly
Make an update thread and tag me im really curious. Will you use this ofr infras? Also why don't you rep fag?
 
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Make an update thread and tag me im really curious. Will you use this ofr infras? Also why don't you rep fag?
I'll prolly make a guide if this works, voluifiline sucks so bad and def need something better, and no i prolly won't do it around my orbitals mainly cuz my eye area isn't actually terrible I'm mainly doing this for my mentolabial angle, and upper lip. Maybe in the future ill try it
 
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I'll prolly make a guide if this works, voluifiline sucks so bad and def need something better, and no i prolly won't do it around my orbitals mainly cuz my eye area isn't actually terrible I'm mainly doing this for my mentolabial angle, and upper lip. Maybe in the future ill try it
Tag me brah:feelshah:
 
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I'll prolly make a guide if this works, voluifiline sucks so bad and def need something better, and no i prolly won't do it around my orbitals mainly cuz my eye area isn't actually terrible I'm mainly doing this for my mentolabial angle, and upper lip. Maybe in the future ill try it
Do tag me as well
 

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