Are there measurable gene expression differences between mechanical vs. hormonal stimulation of craniofacial osteogenesis or nah?

[CoolMan78]

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[rotation]

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yes

mechanical and hormonal stimulation of craniofacial osteogenesis produces completely different gene expression patterns

mechanical load activates mechanotransduction pathways (e.g., Wnt, ECM, matricellular genes)

hormonal/growth factors (e.g., BMPs, IGF‑1) trigger classic osteogenic markers (RUNX2, ALP, COL1A1)

i assume this is what you mean