Benzo users get in here

D

Deleted member 23558

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The study is a bit specific but it shows in essence that GABA is dependent on salt (sodium chloride) to function, and that the strength of GABA activation in the mammalian body can be controlled to an extent by controlling salt intake. It also is another piece of evidence showing the comprehensive view Ray has, and that it's all connected. 8% salt (which I assume is weight of total food) is insane but you don't have to go that high to feel the effects.

They feed the rats different levels of salt for 3 weeks and then measured their responses to GABAergic drugs. As an example, the high salt group had a stronger response to baclofen (chlorinated phenibut) at the same dose than the low salt group.

So, up your salt intake (while keeping your diet the same but upping water to match), and you should in theory feel more relaxed.

Effect of a high-salt diet on gamma-aminobutyric acid-mediated responses in the nucleus tractus solitarius of Sprague-Dawley rats

Effect of a high-salt diet on gamma-aminobutyric acid-mediated responses in the nucleus tractus solitarius of Sprague-Dawley rats - PubMed

Abstract
Previous study using an indirect gamma-aminobutyric acid (GABA) agonist indicated that high salt intake enhances sensitivity of nucleus tractus solitarius (NTS) projecting inhibitory input to rostral ventrolateral medulla sympathoexcitatory neurons. We further investigated the relationship between salt intake and the GABA system in NTS. Sprague-Dawley (S-D) rats consuming high dietary salt (8%) or low dietary salt (0.3%) for 3 weeks were used. Under chloralose-anesthesia, baseline arterial pressure (AP) and heart rate (HR) were similar in both groups. Bilateral injection into NTS of nipecotic acid, GABA(A) receptor agonist (muscimol), or GABA(B) receptor agonist (baclofen) elicited greater pressor responses in high-salt group. GABA(A) receptor antagonist, bicuculline and GABA(B) receptor antagonist, CGP-35348 elicited greater depressor responses. Phenylephrine or nitroprusside (i.v.) elicited similar respective increases or decreases in AP in both groups. Baroreflex sensitivity was similar. Thus, high-salt intake enhances both GABA(A) receptor- and GABA(B) receptor-mediated responses within NTS, thereby inhibiting elevation of AP.

YOLO



@the BULL @Bewusst @apocalypse
 
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Tldr? I Just want to ldar since taking benzos
 
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nerd shit
 
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Tldr? I Just want to ldar since taking benzos
dont take benzos. take baclofen/ phenibut or progesterone derivates/progesterone itself. All these act on GABA-B receptors and increase 5 alpha progesterone in the brain which leads to low inhib and better mood. Benzos made me drowsy and numb , they are so shit. The study is about taking salt to enhance the effects of benzos and GABAergic compounds
 
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i realised I was using clonazepam wrong by taking it with water, it's sublingual apparently and hits way harder
comparable to being slightly drunk
 
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just bloatmaxx your face theory
 
dont take benzos. take baclofen/ phenibut or progesterone derivates/progesterone itself. All these act on GABA-B receptors and increase 5 alpha progesterone in the brain which leads to low inhib and better mood. Benzos made me drowsy and numb , they are so shit.
I cannot not take benzos the hospital controls my levels
I take Depakin and risperidone
 
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I cannot not take benzos the hospital controls my levels
I take Depakin and risperidone
brutal, say goodbye to dopamine levels. no wonder you want to rot.
 
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I cannot not take benzos the hospital controls my levels
I take Depakin and risperidone
Stay strong bull… you will make it
 
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dont take benzos. take baclofen/ phenibut or progesterone derivates/progesterone itself. All these act on GABA-B receptors and increase 5 alpha progesterone in the brain which leads to low inhib and better mood. Benzos made me drowsy and numb , they are so shit. The study is about taking salt to enhance the effects of benzos and GABAergic compounds
Jfl

Screenshot 2023 09 13 22 34 59 06 40deb401b9ffe8e1df2f1cc5ba480b12
 
brutal, say goodbye to dopamine levels. no wonder you want to rot.
Isn't dopamine by rotting the ultimate level? Only zog controlled subhumans Need a position and girls. I can be Happy Just laying on the bed
 
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dont take benzos. take baclofen/ phenibut or progesterone derivates/progesterone itself. All these act on GABA-B receptors and increase 5 alpha progesterone in the brain which leads to low inhib and better mood. Benzos made me drowsy and numb , they are so shit. The study is about taking salt to enhance the effects of benzos and GABAergic compounds
So phenibut and salt= less anxious with no withdrawal or dependency?
 
So phenibut and salt= less anxious with no withdrawal or dependency?
Improving GABAergic tone is probably the mechanism. Taking both salt and magnesium glycinate should reduce withdrawal and dependency. Maybe even cycling progeseterone in between phenibuy days
 
Improving GABAergic tone is probably the mechanism. Taking both salt and magnesium glycinate should reduce withdrawal and dependency. Maybe even cycling progeseterone in between phenibuy days
You shouldn't take this stuff without medical conditions
I'm diagnosed paranoid schizo
 
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Improving GABAergic tone is probably the mechanism. Taking both salt and magnesium glycinate should reduce withdrawal and dependency. Maybe even cycling progeseterone in between phenibuy days
That shit is too sophisticated. Im just gonna stick to benzos, molly, ssris, and alcohol.

//SedatedSigma
 
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you need help
 
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dont take benzos. take baclofen/ phenibut or progesterone derivates/progesterone itself. All these act on GABA-B receptors and increase 5 alpha progesterone in the brain which leads to low inhib and better mood. Benzos made me drowsy and numb , they are so shit. The study is about taking salt to enhance the effects of benzos and GABAergic compounds
Why do u need all this though? Also whats your genuine thoughts regarding pedos ?
 
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I cannot not take benzos the hospital controls my levels
I take Depakin and risperidone
The hospital is forcing you to be a benzo addict that will eventually go through severe benzos withdrawals and have a permanently worsened mental state? It's so messed up it should be for acute use only
 
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They are poisoning you.
The hospital is forcing you to be a benzo addict that will eventually go through severe benzos withdrawals and have a permanently worsened mental state? It's so messed up it should be for acute use only
i feel better than before.
 
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dont take benzos. take baclofen/ phenibut or progesterone derivates/progesterone itself. All these act on GABA-B receptors and increase 5 alpha progesterone in the brain which leads to low inhib and better mood. Benzos made me drowsy and numb , they are so shit. The study is about taking salt to enhance the effects of benzos and GABAergic compounds
Is phenibut or progesterone derivatives even comparable to the potency of benzos? I’m wondering since I have chronic anxiety.
 
Is phenibut or progesterone derivatives even comparable to the potency of benzos? I’m wondering since I have chronic anxiety.
Not as hardcore but yes. For me phenibut is miles better than Ativan or clonazepam
 
Not as hardcore but yes. For me phenibut is miles better than Ativan or clonazepam
What are your thoughts on anti histamines for anxiety such as hydroxyzine
 
What are your thoughts on anti histamines for anxiety such as hydroxyzine
It’s alright problem is they make you drowsy . Theamine, magnesium, progesterone, pregnenolone, cbd oil with 4:1 thc etc are alternatives
 
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You're still here promoting retarded shit lol. Why are curries and chinks so smart in everything but medicine lmfaoo
You don’t know how to respond except calling people retarded. It’s cause you have no actual argument
 
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The hospital is forcing you to be a benzo addict that will eventually go through severe benzos withdrawals and have a permanently worsened mental state? It's so messed up it should be for acute use only
Benzo withdrawal isnt permanent lol i swear there shud be rules against all the idiotic broscience here its legit harmful misinformation
 
You don’t know how to respond except calling people retarded. It’s cause you have no actual argument
The guy literally posted actual science and your response was "and"

Nigga

Thought curries were high iq jfl
 
The guy literally posted actual science and your response was "and"

Nigga

Thought curries were high iq jfl
You’re decreasing my estimation of your iq every second thing you post
 
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You shouldn't take this stuff without medical conditions
I'm diagnosed paranoid schizo
Ironic how one of the most insane users here has the most reasonable post
 
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Benzo withdrawal isnt permanent lol i swear there shud be rules against all the idiotic broscience here its legit harmful misinformation
Scaring someone off using benzos for months on end is HARMFUL misinformation? I've gone through benzo withdrawal but it wasn't that bad because I wasn't stupid and only used for 14 days in a row If he has been using them for months and stops suddenly he will get seizures and possibly permanent brain damage, you have to taper off very slowly the cons outweigh the pros no one needs benzos long term
 
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You dont understanding studies lol.
Doing the same thing again. Making accusations without addressing anything about the topic at hand. One trick pony shit innit crony
 
Scaring someone off using benzos for months on end is HARMFUL misinformation? I've gone through benzo withdrawal but it wasn't that bad because I wasn't stupid and only used for 14 days in a row If he has been using them for months and stops suddenly he will get seizures and possibly permanent brain damage, you have to taper off very slowly the cons outweigh the pros no one needs benzos long term
Source for benzo withdrawal being permanent please
 
Scaring someone off using benzos for months on end is HARMFUL misinformation? I've gone through benzo withdrawal but it wasn't that bad because I wasn't stupid and only used for 14 days in a row If he has been using them for months and stops suddenly he will get seizures and possibly permanent brain damage, you have to taper off very slowly the cons outweigh the pros no one needs benzos long term
You don't suddenly stop you gradually lower the dose
 
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Doing the same thing again. Making accusations without addressing anything about the topic at hand. One trick pony shit innit crony
Youre oversimplifying one of the most complex scientific topics jfl
 
It’s alright problem is they make you drowsy . Theamine, magnesium, progesterone, pregnenolone, cbd oil with 4:1 thc etc are alternatives
Interesting, btw this is off topic but do you know of anyways to increase androgen receptors and senditivity?
 

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