Bloat mk677

[yan1s…]

I’m looking for some opinions. I recently had blood work showing slightly elevated aldosterone (263 pg/mL), normal renin (10.2 pg/mL), and an aldosterone/renin ratio around 40.

For context, I took MK-677 (ibutamoren) for about 1 month a few months ago, then stopped. Since then, I’ve had noticeable facial fluctuations—some days it looks normal, other days more “bloated” or full.

Could a mild aldosterone/RAAS imbalance like this be contributing to fluctuating facial water retention, even if values aren’t clearly pathological? Has anyone seen something similar after MK-677? Will it come back to normal

 

[browridge]

youre gonna explode

 

[yan1s…]

youre gonna explode

Nice

 

[browridge]

Nice

unlucky budyd

 

[Milktard]

yes of course the aldosterone is contributing to facial bloating, if its been 2 months+ and those are your labs then it probably isnt from the mk. i was on mk and honestly didnt feel facially bloated whenever i didn't eat slop after 1 month but don't got labs to back it up

what is your sodium to potassium ratio through your diet and are you doing cardio?

if its that big of a deal for you eplerenone can probably easily fix your bloat and labs but that might be overkill since yours are slightly elevated and can probably return normal if you have good habits

 

[yan1s…]

unlucky budyd

yes of course the aldosterone is contributing to facial bloating, if its been 2 months+ and those are your labs then it probably isnt from the mk. i was on mk and honestly didnt feel facially bloated whenever i didn't eat slop after 1 month but don't got labs to back it up

what is your sodium to potassium ratio through your diet and are you doing cardio?

if its that big of a deal for you eplerenone can probably easily fix your bloat and labs but that might be overkill since yours are slightly elevated and can probably return normal if you have good habits

Yeah I get your point, but in my case the timeline suggests it’s linked to MK. I took MK-677 for about 1 month and stopped about 4–5 months ago. Right after stopping I had clear fluid retention with pitting edema (lasting minutes), which has since improved a lot (now only a few seconds), but I still have day-to-day facial fluctuations.

My labs show slightly elevated aldosterone, normal renin, ratio ~40, so it doesn’t really look like primary hyperaldosteronism. It feels more like a functional RAAS adaptation rather than a fixed issue.

Diet is stable (no big sodium swings) and cardio is moderate. I also started eplerenone recently but since things are already improving, I’m not sure it’s needed long term.

I’m more wondering if a post-MK RAAS dysregulation could explain these lingering but improving fluctuations.

 

[Milktard]

Yeah I get your point, but in my case the timeline suggests it’s linked to MK. I took MK-677 for about 1 month and stopped about 4–5 months ago. Right after stopping I had clear fluid retention with pitting edema (lasting minutes), which has since improved a lot (now only a few seconds), but I still have day-to-day facial fluctuations.

My labs show slightly elevated aldosterone, normal renin, ratio ~40, so it doesn’t really look like primary hyperaldosteronism. It feels more like a functional RAAS adaptation rather than a fixed issue.

Diet is stable (no big sodium swings) and cardio is moderate. I also started eplerenone recently but since things are already improving, I’m not sure it’s needed long term.

I’m more wondering if a post-MK RAAS dysregulation could explain these lingering but improving fluctuations.

if its improving then you're chillin if its getting worse then thats a whole different problem, your body is probably taking longer to normalize than others from the mk

if you stay hydrated with electrolytes, adequate sleep and dont eat slop then it will get better

 

[Renophobeadoobe]

can't say much about ur case im j as confused tbh

after hopping off recently my breathing is still shit but it improved a tad bit

im still getting bloated too which is fucking retarded

 

[yan1s…]

if its improving then you're chillin if its getting worse then thats a whole different problem, your body is probably taking longer to normalize than others from the mk

if you stay hydrated with electrolytes, adequate sleep and dont eat slop then it will get better

Yeah I get that, and I agree it improving is a good sign. I’m wondering if I might have changed my system long-term, or if this usually fully normalizes with time.

 

[yan1s…]

can't say much about ur case im j as confused tbh

after hopping off recently my breathing is still shit but it improved a tad bit

im still getting bloated too which is fucking retarded

How many time since u stopped

 

[Renophobeadoobe]

How many time since u stopped

just 2 brah

i did try mk last year though and the sides lasted a while its fucking brutal

im hoping its the same case and eventually itll subside

wishing you the best this shit is literally the worst

 

[yan1s…]

just 2 brah

i did try mk last year though and the sides lasted a while its fucking brutal

im hoping its the same case and eventually itll subside

wishing you the best this shit is literally the worst

When u hopped off last year did the bloat stay for months
And tbh ill never hop on that shi ever again , no benefits at all

 

[yan1s…]

Bump

 

[polarpop]

tu pue

 

[yan1s…]

tu pue

bztmr