Can AIs prevent high e2 from HCG?

[Napoleon1800]

HCG increased intratesticular testosterone and thus intratesticular estradiol, and inside the tested aromatase activity is very high

AIs cannot penetrate intratesticular tissue effectively, only peripheral aromatisation

Does this mean then taking an AI is pointless in preventing high e2 resulting from hcg?

 

[killyourselfASAP]

my dad jus called me a faggot

 

[Napoleon1800]

my dad jus called me a faggot

Very useful to my question

 

[dart44511]

HCG increased intratesticular testosterone and thus intratesticular estradiol, and inside the tested aromatase activity is very high

AIs cannot penetrate intratesticular tissue effectively, only peripheral aromatisation

Does this mean then taking an AI is pointless in preventing high e2 resulting from hcg?

genuinely İ have no clue, tag some high iq niggas to answer the question

 

[Triax]

HCG increased intratesticular testosterone and thus intratesticular estradiol, and inside the tested aromatase activity is very high

AIs cannot penetrate intratesticular tissue effectively, only peripheral aromatisation

Does this mean then taking an AI is pointless in preventing high e2 resulting from hcg?

 

[Napoleon1800]

@hej1377 @chadisbeingmade @Kelly Oubre Jr

 

[mewzilla]

you can use aromatase blocking cream or wtv its called locally

 

[LTNUser]

You could've tagged @aids and @eon as well

@hej1377 @chadisbeingmade @Kelly Oubre Jr

 

[Napoleon1800]

You could've tagged @aids and @eon as well

Tbh I don’t even know most users here anymore most of the ones I knew are inactive/been deleted

the forum has changed a lot

 

[mewzilla]

Tbh I don’t even know most users here anymore most of the ones I knew are inactive/been deleted

the forum has changed a lot

u can tag me and rotations

 

[hej1377]

No it cannot really do so well,@mewzilla suggestion may be good tho altough i dont know much about the ai creams

Also mewzilla do you think an ai cream is good enough to prevent gyno on higher doses of test so you dont have to risk taking to much ai and feeling like shit?

 

[mewzilla]

No it cannot really do so well,@mewzilla suggestion may be good tho altough i dont know much about the ai creams

Also mewzilla do you think an ai cream is good enough to prevent gyno on higher doses of test so you dont have to risk taking to much ai and feeling like shit?

idk much about gyno since i dont plan to run test, but i dont think that the local e2 you'd be inhibiting in your breasts would prevent gyno, since gyno isnt fat or anything that meddles with estrogen but just breast tissue. idk tho, always worth a try i guess.

 

[Napoleon1800]

idk much about gyno since i dont plan to run test, but i dont think that the local e2 you'd be inhibiting in your breasts would prevent gyno, since gyno isnt fat or anything that meddles with estrogen but just breast tissue. idk tho, always worth a try i guess.

I have low-normal e2 (16.6pg/ml) but I have gyno

My prolactin is 9.6

 

[Napoleon1800]

No it cannot really do so well,@mewzilla suggestion may be good tho altough i dont know much about the ai creams

Also mewzilla do you think an ai cream is good enough to prevent gyno on higher doses of test so you dont have to risk taking to much ai and feeling like shit?

I may skip hcg then and accept the shrunken balls

Can balls return to baseline size and semen output and fertility from hcg after a few weeks of a blast without it and then going on a cruise?

 

[Ogionth]

HCG increased intratesticular testosterone and thus intratesticular estradiol, and inside the tested aromatase activity is very high

AIs cannot penetrate intratesticular tissue effectively, only peripheral aromatisation

Does this mean then taking an AI is pointless in preventing high e2 resulting from hcg?

Well the thing is, intratesticular E2 is already about 88 times higher than serum in normal men.

When you use exog testosterone, and then use HCG for LH activity again, you're just making the intratesticular E2 levels come back (since the exog T caused a negative feedback loop and thus LH was lowered or dropped to 0) to what they naturally were/are supposed to be.

So not only is HCG not making it abnormally high but an abnormally high intratesticular E2 only has effects on fertility, not your whole body, so you don't need to worry about that.

Hopefully, you get it.

So an AI has nothing to do with it, you don't need to lower intratesticular E2.

 

[hej1377]

I may skip hcg then and accept the shrunken balls

Can balls return to baseline size and semen output and fertility from hcg after a few weeks of a blast without it and then going on a cruise?

Yes,under 6 months you can pretty much be guaranted to have 0 permanent effects after hcg

 

[Ogionth]

you can use aromatase blocking cream or wtv its called locally

Do not do this.

Read my reply.

 

[mewzilla]

Do not do this.

Read my reply.

yeah i just did, youre right lol

i saw it mentioned in another thread and thought to mention it. havent done any real research on it. ur smarter than me

 

[Napoleon1800]

Do not do this.

Read my reply.

So hcg has no risk of significantly raising serum e2 levels or affecting gyno or growth plates?

 

[slaters]

Well the thing is, intratesticular E2 is already about 88 times higher than serum in normal men.

View attachment 4328092

When you use exog testosterone, and then use HCG for LH activity again, you're just making the intratesticular E2 levels come back (since the exog T caused a negative feedback loop and thus LH was lowered or dropped to 0) to what they naturally were/are supposed to be.

So not only is HCG not making it abnormally high but an abnormally high intratesticular E2 only has effects on fertility, not your whole body, so you don't need to worry about that.

Hopefully, you get it.

So an AI has nothing to do with it, you don't need to lower intratesticular E2.

Chad

 

[Ogionth]

So hcg has no risk of significantly raising serum e2 levels or affecting gyno or growth plates?

HCG indeed raises serum E2 but you said you're using AI for that during cycle (and Exog test increases serum e2 too obviously) but your question was about intratesticular E2.

if you're using HCG after the cycle ended, then if you dont underdose or overdose, it will bring serum E2 and serum T levels to normal ranges.

But if you overdose HCG, then it will signifcantly increase serum E2 levels obviously which will require AI to mitigate but why would you overdose it?

 

[Napoleon1800]

HCG indeed raises serum E2 but you said you're using AI for that during cycle (and Exog test increases serum e2 too obviously) but your question was about intratesticular E2.

if you're using HCG after the cycle ended, then if you dont underdose or overdose, it will bring serum E2 and serum T levels to normal ranges.

But if you overdose HCG, then it will signifcantly increase serum E2 levels obviously which will require AI to mitigate but why would you overdose it?

I won’t overdose hcg I meant using it during cycle

I already have gyno at 16.6pg/ml which is strange but regardless I’m going to be running 600mg test a week and hgh, plus Aromasin 12.5mg a day. Now height growth I don’t have much hope for I mean if it happens it happens but I’m actively going to be trying to grow my frame (including my clavicles), and apart from preventing my gyno increasing and bloat and such, I also want to prevent growth plate closure of my clavicles and wherever else they may be open
I was planning to use hcg 250ius EOD on the blast to maintain testicular volume but I was worried if it may drastically impact my e2 or raise my e2 intratesticular where AI can’t effect it

 

[Spieldren]

does this mean i can use as much AIs as i want and get all my e2 from hcg only?

 

[Ogionth]

I won’t overdose hcg I meant using it during cycle

I already have gyno at 16.6pg/ml which is strange but regardless I’m going to be running 600mg test a week and hgh, plus Aromasin 12.5mg a day. Now height growth I don’t have much hope for I mean if it happens it happens but I’m actively going to be trying to grow my frame (including my clavicles), and apart from preventing my gyno increasing and bloat and such, I also want to prevent growth plate closure of my clavicles and wherever else they may be open
I was planning to use hcg 250ius EOD on the blast to maintain testicular volume but I was worried if it may drastically impact my e2 or raise my e2 intratesticular where AI can’t effect it

Just do what you wanna do ( HCG every other day 250 iu), that's fine .

It won't do any harm, no it won't significantly raise your intratesticular e2 to supraphysiological levels and even if it did, you wouldn't feel the effects.

 

[Napoleon1800]

Just do what you wanna do ( HCG every other day 250 iu), that's fine .

It won't do any harm, no it won't significantly raise your intratesticular e2 to supraphysiological levels and even if it did, you wouldn't feel the effects.

Is hcg desensitisation legit? Should I cycle it?

 

[Ogionth]

Is hcg desensitisation legit? Should I cycle it?

Yes, it's legit but it's dose dependent, so at your dosage, it's gonna be very low and since you're cycling exog T and hcg, the gap between cycles will likely suffice for your desensitization recovery if there is any small amount of desensitization to begin wih.

 

[Napoleon1800]

Yes, it's legit but it's dose dependent, so at your dosage, it's gonna be very low and since you're cycling exog T and hcg, the gap between cycles will likely suffice for your desensitization recovery if there is any small amount of desensitization to begin wih.

I’m going to be blasting and cruising. Should I go off whenever I end my blast?

 

[Kelly Oubre Jr]

Well the thing is, intratesticular E2 is already about 88 times higher than serum in normal men.

View attachment 4328092

When you use exog testosterone, and then use HCG for LH activity again, you're just making the intratesticular E2 levels come back (since the exog T caused a negative feedback loop and thus LH was lowered or dropped to 0) to what they naturally were/are supposed to be.

So not only is HCG not making it abnormally high but an abnormally high intratesticular E2 only has effects on fertility, not your whole body, so you don't need to worry about that.

Hopefully, you get it.

So an AI has nothing to do with it, you don't need to lower intratesticular E2.

yeah good answer also @Napoleon1800 when you said

inside the tested aromatase activity is very high

this just isnt true most aromatase activity is in fat so hcg and ai are gonna act completely seperately and its very simple, hcg can make e2 go up and ai can make e2 go down, theres no special interactions where they cancel each others effects or anything