can honey megadoses be bad ?

[Youㅤ]

im eating around 30% of my calories from honey

 

[Mrinfinityx]

idk exactly what ur saying , but yes u want good colored salmon with more astaxathin . the farmed salmon haas synthetic astaxanthin which is different isomer like more bent ones & less good at antioxidant

Generally homogenous color all pink is the sign that something is unnatural, u want nuances of pink and red ideally from ur source

 

[thereallegend]

does it increase LH ? if so how to ameliorate ?

Luteinizing hormone is good for you. Most of that anti aging research the Jew Dr. Sinclair is complete rubbish.

 

[Mrinfinityx]

No, eat as much as you want. Asjonus used raw honey to help diabetics

All is a matter of dose, like sun or red light therapy, u want homeostasis and equilibrum in everything

 

[Youㅤ]

Generally homogenous color all pink is the sign that something is unnatural, u want nuances of pink and red ideally from ur source

i am considering supplementing astaxanthin for lipid membrane antioxidant & maybe DHT lowering

 

[Youㅤ]

Luteinizing hormone is good for you. Most of that anti aging research the Jew Dr. Sinclair is complete rubbish.

ive never heard david talk about LH . i was baseing it off of jeff bowles' article

NEW STUDY DISPROVES ALL MAINSTREAM THEORIES OF AGING-AND REVEALS THE NEW: PROGRAMMED LOSS OF CELLULAR DIFFERENTIATION THEORY OF AGING - Jeff T Bowles

Before we get started let me just whet your appetite about what is contained in the rest of this article. The results of the most important study on aging EVER, that will be the most important study of aging for all time- have just been released! Steve Horvath's : Universal DNA methylation age...

jefftbowles.com

 

[Mrinfinityx]

i am considering supplementing astaxanthin for lipid membrane antioxidant & maybe DHT lowering

Still full head of hair at 30 yo with a NW3 father and bald grandfather so u cant go wrong

 

[Mrinfinityx]

ive never heard david talk about LH . i was baseing it off of jeff bowles' article

NEW STUDY DISPROVES ALL MAINSTREAM THEORIES OF AGING-AND REVEALS THE NEW: PROGRAMMED LOSS OF CELLULAR DIFFERENTIATION THEORY OF AGING - Jeff T Bowles

Before we get started let me just whet your appetite about what is contained in the rest of this article. The results of the most important study on aging EVER, that will be the most important study of aging for all time- have just been released! Steve Horvath's : Universal DNA methylation age...

jefftbowles.com

If u take melatonin maximum 1 mg, ideally near 0,5 mg so u want potentially the minimal effective dosage, otherwise u are interfering with LH pathway endogen metabolism and u dont want that

Melatonin inhibits release of luteinizing hormone (LH) via decrease of [Ca2+]i and cyclic AMP - PubMed

The role of [Ca2+]i and cAMP in transduction of the melatonin inhibitory effect on GnRH-induced LH release from neonatal rat gonadotrophs has been studied, because melatonin inhibits the increase of both intracellular messengers. Treatments increasing Ca2+ influx (S(-) Bay K8644 or KCI) or cAMP...

pubmed.ncbi.nlm.nih.gov

Physiology of the Pineal Gland and Melatonin - Endotext - NCBI Bookshelf

Melatonin potentiates testosterone-induced suppression of luteinizing hormone secretion in normal men - PubMed

A total of 12 healthy adult men were recruited to investigate the effect of exogenous melatonin on the sensitivity of the hypothalamo-pituitary axis to sex steroid negative feedback. The experiment consisted of a double-blind, randomized cross-over trial during which all subjects received 100 mg...

pubmed.ncbi.nlm.nih.gov

Abnormal melatonin secretion in hypogonadal men: the effect of testosterone treatment - PubMed

These data indicate that male patients with GnRH deficiency have increased nocturnal melatonin secretion while in hypergonadotrophic hypogonadal males melatonin secretion is decreased. Testosterone treatment normalized melatonin concentrations in these patients. Taken together, the results...

pubmed.ncbi.nlm.nih.gov

The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects - PubMed

Exogenous melatonin (0.5-10 mg) has been shown to entrain the free-running circadian rhythms of some blind subjects. The aim of this study was to assess further the entraining effects of a daily dose of 0.5 mg melatonin on the cortisol rhythm and its acute effects on subjective sleep in blind...

pubmed.ncbi.nlm.nih.gov

 

[Youㅤ]

If u take melatonin maximum 1 mg, ideally near 0,5 mg so u want potentially the minimal effective dosage, otherwise u are interfering with LH pathway endogen metabolism and u dont want that

Melatonin inhibits release of luteinizing hormone (LH) via decrease of [Ca2+]i and cyclic AMP - PubMed

The role of [Ca2+]i and cAMP in transduction of the melatonin inhibitory effect on GnRH-induced LH release from neonatal rat gonadotrophs has been studied, because melatonin inhibits the increase of both intracellular messengers. Treatments increasing Ca2+ influx (S(-) Bay K8644 or KCI) or cAMP...

pubmed.ncbi.nlm.nih.gov

Physiology of the Pineal Gland and Melatonin - Endotext - NCBI Bookshelf

i take 40 mg melatonin

i want inhibit LH , but the data in humans is inconcluseive to my knowledge

 

[beefliverontop]

ur right it not have many vitamins or minerals . although it has some . the antioxidants , enzymes , phytonutrients might be beneficial

200 grams honey
View attachment 3010775
View attachment 3010776

yes,
you are still on the rape list tho.... sadly
sorry...

 

[Youㅤ]

"Melatonin inhibits GnRH-induced release of LH and FSH from the neonatal, but not the adult, rat anterior pituitary gland. This action of melatonin is mediated by the specific high-affinity membrane-bound receptors that are absent in adult rats. The intracellular mechanism of melatonin action involves a decrease in intracellular calcium [Ca2+]i in the gonadotrophs; melatonin inhibits GnRH-induced Ca2+ release from endoplasmic reticulum as well as Ca2+ influx through voltage-sensitive channels. Melatonin also inhibits GnRH-induced accumulation of cAMP, which may result in the decreased influx of Ca2+, because cAMP, acting through protein kinase A, stimulates Ca2+ influx into the gonadotrophs. This age-dependent effect of melatonin on gonadotrophin release from the pituitary may be involved in the timing of puberty."

maybe i need reprogram epigenetics & then melatonin inhibit LH more

 

[Htobrother]

I Megadose Pussy nothing happened

 

[Htobrother]

"Melatonin inhibits GnRH-induced release of LH and FSH from the neonatal, but not the adult, rat anterior pituitary gland. This action of melatonin is mediated by the specific high-affinity membrane-bound receptors that are absent in adult rats. The intracellular mechanism of melatonin action involves a decrease in intracellular calcium [Ca2+]i in the gonadotrophs; melatonin inhibits GnRH-induced Ca2+ release from endoplasmic reticulum as well as Ca2+ influx through voltage-sensitive channels. Melatonin also inhibits GnRH-induced accumulation of cAMP, which may result in the decreased influx of Ca2+, because cAMP, acting through protein kinase A, stimulates Ca2+ influx into the gonadotrophs. This age-dependent effect of melatonin on gonadotrophin release from the pituitary may be involved in the timing of puberty."

maybe i need reprogram epigenetics & then melatonin inhibit LH more

Are you a Rat?

 

[Mrinfinityx]

i take 40 mg melatonin

i want inhibit LH , but the data in humans is inconcluseive to my knowledge

Even if testosterone is pro aging i won't risk it to not catalyze bone resorption with aging, as aging is mainly induced by facial bone resorption and is strongly correlated to androgens, growth hormone and oestrogens levels but ur oestrogen levels come mainly from aromatase process of ur testosterone anyway, better focusing on bone conservation than coping with retin A sunscreen and avoiding sun exposure, the latter that is actually good for bones in certain amounts of irrandiance JFL

Physiology, Luteinizing Hormone - PubMed

Luteinizing hormone (LH) is a glycoprotein hormone that is co-secreted along with follicle-stimulating hormone by the gonadotrophin cells in the adenohypophysis (anterior pituitary). Luteinizing hormone is a part of a neurological pathway comprised of the hypothalamus, the pituitary gland, and...

pubmed.ncbi.nlm.nih.gov

Botox, fillers and other surgical procedures on the soft tissues cant cope this, u will do ur age while being gay alien uncanny maxxed no matter what

 

[Rigged]

Chug mustard for efficiency

 

[Youㅤ]

Even if testosterone is pro aging i won't risk it to not catalyze bone resorption with aging, as aging is mainly induced by facial bone resorption and is strongly correlated to androgens, growth hormone and oestrogens levels but ur ostreogens levels come mainly from aromatase process of ur testosterone anyway, better focusing on bone conservation than coping with retin A sunscreen and avoiding sun exposure, the latter that is actually good for bones in certain amounts of irrandiance JFL

View attachment 3010911View attachment 3010914

LH increase with ageing

in youth bones r not atrophying

 

[Youㅤ]

Even if testosterone is pro aging i won't risk it to not catalyze bone resorption with aging, as aging is mainly induced by facial bone resorption and is strongly correlated to androgens, growth hormone and oestrogens levels but ur oestrogen levels come mainly from aromatase process of ur testosterone anyway, better focusing on bone conservation than coping with retin A sunscreen and avoiding sun exposure, the latter that is actually good for bones in certain amounts of irrandiance JFL

Physiology, Luteinizing Hormone - PubMed

Luteinizing hormone (LH) is a glycoprotein hormone that is co-secreted along with follicle-stimulating hormone by the gonadotrophin cells in the adenohypophysis (anterior pituitary). Luteinizing hormone is a part of a neurological pathway comprised of the hypothalamus, the pituitary gland, and...

pubmed.ncbi.nlm.nih.gov

View attachment 3010911View attachment 3010914

Botox, fillers and other surgical procedures on the soft tissues cant cope this, u will do ur age while being gay alien uncanny maxxed no matter what

sorry but this is really low IQ

just clench for bones lol . & anti ageing overall prevents bone loss

 

[Rigged]

Even if testosterone is pro aging i won't risk it to not catalyze bone resorption with aging, as aging is mainly induced by facial bone resorption and is strongly correlated to androgens, growth hormone and oestrogens levels but ur oestrogen levels come mainly from aromatase process of ur testosterone anyway, better focusing on bone conservation than coping with retin A sunscreen and avoiding sun exposure, the latter that is actually good for bones in certain amounts of irrandiance JFL

Physiology, Luteinizing Hormone - PubMed

Luteinizing hormone (LH) is a glycoprotein hormone that is co-secreted along with follicle-stimulating hormone by the gonadotrophin cells in the adenohypophysis (anterior pituitary). Luteinizing hormone is a part of a neurological pathway comprised of the hypothalamus, the pituitary gland, and...

pubmed.ncbi.nlm.nih.gov

View attachment 3010911View attachment 3010914

Botox, fillers and other surgical procedures on the soft tissues cant cope this, u will do ur age while being gay alien uncanny maxxed no matter what

What in the low iq understanding of gerontology

 

[Mrinfinityx]

LH increase with ageing

in youth bones r not atrophying

Indeed that s strange, maybe to cope the receptors sensitivity depletion, like for the insulin levels and desensitivation in diabete, since testosterone is falling apart with age

 

[thereallegend]

ive never heard david talk about LH . i was baseing it off of jeff bowles' article

NEW STUDY DISPROVES ALL MAINSTREAM THEORIES OF AGING-AND REVEALS THE NEW: PROGRAMMED LOSS OF CELLULAR DIFFERENTIATION THEORY OF AGING - Jeff T Bowles

Before we get started let me just whet your appetite about what is contained in the rest of this article. The results of the most important study on aging EVER, that will be the most important study of aging for all time- have just been released! Steve Horvath's : Universal DNA methylation age...

jefftbowles.com

DNRD

 

[Youㅤ]

Indeed that s strange, maybe to cope the receptors sensitivity depletion, like for the insulin levels and desensitivation in diabete, since testosterone is falling apart with age

t doesnt decrease due to ageing per se

A validated age-related normative model for male total testosterone shows increasing variance but no decline after age 40 years - PubMed

The diagnosis of hypogonadism in human males includes identification of low serum testosterone levels, and hence there is an underlying assumption that normal ranges of testosterone for the healthy population are known for all ages. However, to our knowledge, no such reference model exists in...

pubmed.ncbi.nlm.nih.gov

read jeff bowles

 

[Youㅤ]

DNRD

read jeff bowles

!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

 

[Mrinfinityx]

What in the low iq understanding of gerontology

U are here to criticate but i dont see any arguments still, explain urself

 

[Mrinfinityx]

t doesnt decrease due to ageing per se

A validated age-related normative model for male total testosterone shows increasing variance but no decline after age 40 years - PubMed

The diagnosis of hypogonadism in human males includes identification of low serum testosterone levels, and hence there is an underlying assumption that normal ranges of testosterone for the healthy population are known for all ages. However, to our knowledge, no such reference model exists in...

pubmed.ncbi.nlm.nih.gov

read jeff bowles

Ofc i didnt say it cant stagnate or be maintained during some times until the andropose come finishing u off, u are more health conscious in general with age so it can be explained by this factor already

 

[thereallegend]

!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

You gotta summarize it for me

 

[Youㅤ]

Ofc i didnt say it cant stagnate or be maintained during some times until the andropose come finishing u off, u are more health conscious in general with age so it can be explained by this factor already

nigga , andropause is cope

 

[Mrinfinityx]

What in the low iq understanding of gerontology

Go see the skin quality of the TRT abusers with overtraining on top and tell me it dont act as a proaging factor for skin health, i dont take into account the antiaging benefits for bones at a moderate amount, all u need is optimal physiological response and dosages, as homeostasis and equilibrum is the nature of biology and life

 

[Mrinfinityx]

nigga , andropause is cope

View attachment 3010933

Well the tendency is still falling even if way tinnier than expected, even some purcents matter for me
What about growth hormone now ?

Growth Hormone in Aging - Endotext - NCBI Bookshelf

 

[Youㅤ]

What about growth hormone and oestrogens now ?

just supplement melatonin mayeb that bring GH up without accelerateing ageing

thots on estriol ?

 

[IAMNOTANINCEL]

if you feel good doing that then its fine simple

 

[Mrinfinityx]

just supplement melatonin mayeb that bring GH up without accelerateing ageing

thots on estriol ?

That s why i take melatonin, glycin and citrulin malate for arginin, to optimize my HGH production

Stimulatory effect of glycine on human growth hormone secretion - PubMed

Glycine (250 ml 0.3 M glycine) was administered orally to 19 nonobese normal subjects and 12 subjects with partial gastrectomy. In the normal subjects, a clear and significant increase of serum human growth hormone (hGH) level was observed (p less than 0.001), whereas serum immunoreactive...

pubmed.ncbi.nlm.nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712012/

Melatonin stimulates growth hormone secretion through pathways other than the growth hormone-releasing hormone - PubMed

Our data indicate that oral administration of melatonin to normal human males increases basal GH release and GH responsiveness to GHRH through the same pathways as pyridostigmine. Therefore it is likely that melatonin plays this facilitatory role at the hypothalamic level by inhibiting...

pubmed.ncbi.nlm.nih.gov

 

[Youㅤ]

That s why i take melatonin, glycin and citrulin malate for arginin, to optimize my HGH production

how to inhibit IGF-1 signalling ?

 

[Mrinfinityx]

how to inhibit IGF-1 signalling ?

Why do u want to inhibit it ?

Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis - PubMed

Background. Growth hormone (GH) and insulin-like growth factor (IGF-1) are fundamental in skeletal growth during puberty and bone health throughout life. GH increases tissue formation by acting directly and indirectly on target cells; IGF-1 is a critical mediator of bone growth. Clinical studies...

pubmed.ncbi.nlm.nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132406/

U dont need to megadose carbs for that anyway, just a decent amount with healthy fats and dairy products consumption

 

[Youㅤ]

Why do u want to inhibit it ?

Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis - PubMed

Background. Growth hormone (GH) and insulin-like growth factor (IGF-1) are fundamental in skeletal growth during puberty and bone health throughout life. GH increases tissue formation by acting directly and indirectly on target cells; IGF-1 is a critical mediator of bone growth. Clinical studies...

pubmed.ncbi.nlm.nih.gov

IGF-1 deficient transgenic mice r literally like one of the longest lived ...

IGF-1 inhibition is the most obvious strategy to slow ageing

 

[Mrinfinityx]

IGF-1 deficient transgenic mice r literally like one of the longest lived ...

IGF-1 inhibition is the most obvious strategy to slow ageing

Well u will live longer but with subpar bones, what s the point if u want to looksmax until death ?

 

[Youㅤ]

Well u will live longer but with subpar bones, what s the point if u want to looksmax until death ?

in adults bones r barely developing

just inhibit osteoclastogenesis if u want to preserve bone mass

 

[Mrinfinityx]

in adults bones r barely developing

just inhibit osteoclastogenesis if u want to preserve bone mass

That s what i am doing, i even gain bonemass from 24 to 29 yo with my protocol, it was a good satisfaction to notice this considering i am way over the development stage

 

[Youㅤ]

That s what i am doing, i even gain bonemass from 24 to 29 yo with my protocol, it was a good satisfaction to notice this considering i am way over the development stage

View attachment 3010961

i dont see a difference in size or shape , did density increase or is it just difference shade ?

 

[Mrinfinityx]

i dont see a difference in size or shape , did density increase or is it just difference shade ?

Density is more white so more concentrated minerals, the chin is fuller under the teeth and taller, the gonions are more curved with no increase of antegonial notch angle or loss of vertical mandibular height

 

[Rigged]

just supplement melatonin mayeb that bring GH up without accelerateing ageing

thots on estriol ?

I cant @ u check my recent post

 

[Youㅤ]

I cant @ u check my recent post

copy paste to tag

 

[Rigged]

U are here to criticate but i dont see any arguments still, explain urself

Test upregulates osteoblastogenesis, counteracts osteoclastic activity also aging involves shit like telomere attrition, mitochondrial ROS-induced damage, and chronic NF-KB-controlled inflammation, not just facial bone resorption. Androgens and estrogens both together manage RANKL/OPG pathways for bone homeostasis

 

[Mrinfinityx]

Test upregulates osteoblastogenesis, counteracts osteoclastic activity also aging involves shit like telomere attrition, mitochondrial ROS-induced damage, and chronic NF-KB-controlled inflammation, not just facial bone resorption. Androgens and estrogens both together manage RANKL/OPG pathways for bone homeostasis

I am totally agreeing but some here are going totally overboard physiological dosages thinking more is better shooting themselves with insane amount of excess TRT thinking they will hack genetics and becoming skin moggers, pure delusion as for pratically anything in biology there is biphasic dose response for effectiveness

Androgens: biphasic dose responses - PubMed

Testosterone was reported to affect a variety of reproductive endpoints. More notable were the effects of dihydrotestosterone on cell proliferation in the prostate cancer cell model LNCaP and Sertoli cell function. Testosterone production was also biphasically affected by prolactin that was...

pubmed.ncbi.nlm.nih.gov

https://www.sciencedirect.com/science/article/abs/pii/0303720793901162

 

[Rigged]

I am totally agreeing but some here are going totally overboard physiological dosages thinking more is better shooting themselves with insane amount of excess TRT thinking they will hack genetics and becoming skin moggers, pure delusion as for pratically anything in biology there is biphasic dose response for effectiveness

I roid for big muscle

 

[Youㅤ]

I roid for big muscle

better strategy is inhibiting myostatin

 

[Mrinfinityx]

I roid for big muscle

Well u know what u go for at least

 

[Rigged]

better strategy is inhibiting myostatin

Both work differently one of them turns up the max the other increases how fast u get to the max

 

[Mrinfinityx]

Both work differently one of them turns up the max the other increases how fast u get to the max

Anyway u dont need mogger muscles for foids, so do u have any other hidden motivation ?

 

[Rigged]

Anyway u dont need mogger muscles for foids, so do u have any other hidden motivation ?

I have methods to increase my dick to 9 inches so i want to scare women when a 600 lbs 12% bf guy pulls out a hammer

 

[Mrinfinityx]

I have methods to increase my dick to 9 inches so i want to scare women when a 600 lbs 12% bf guy pulls out a hammer

Are u talking about PE or pump or recent injections methods ?

 

[Rigged]

Are u talking about PE or pump or recent injections methods ?

Dr.Hinks method i have it on my profile posts if u scroll down to day 3 ull know what i mean when u open my profile posts