CJC1295 & DAC

[Sachlichkeit]

"After a single injection of CJC-1295, there were dose-dependent increases in mean plasma GH concentrations by 2- to 10-fold for 6 d or more and in mean plasma IGF-I concentrations by 1.5- to 3-fold for 9-11 d. The estimated half-life of CJC-1295 was 5.8-8.1 d. After multiple CJC-1295 doses, mean IGF-I levels remained above baseline for up to 28 d. No serious adverse reactions were reported."

GH rose 2–10× and stayed elevated for 6 days or longer, while IGF-1 increased 1.5–3× and remained elevated for 10 days.

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults - PubMed

Subcutaneous administration of CJC-1295 resulted in sustained, dose-dependent increases in GH and IGF-I levels in healthy adults and was safe and relatively well tolerated, particularly at doses of 30 or 60 microg/kg. There was evidence of a cumulative effect after multiple doses. These data...

pubmed.ncbi.nlm.nih.gov

Acromegaly comes from sustained GH levels over the course of YEARS. Not by pinning exogenous GH which is partially pulsatile, the spike in IGF1 happens shortly after injection as actual GH only sits in the body for around 20 minutes and slowly decreases

MK667, and CJC+1295DAC, because they are GH secretagogues that keep IGF-1 elevated for 24hs AND flatten the endogenous peaks & troughs, are the closest one can get to acromegaly.

Not saying acromegaly is good, do with this information what u will

 

[infrainfra]

"After a single injection of CJC-1295, there were dose-dependent increases in mean plasma GH concentrations by 2- to 10-fold for 6 d or more and in mean plasma IGF-I concentrations by 1.5- to 3-fold for 9-11 d. The estimated half-life of CJC-1295 was 5.8-8.1 d. After multiple CJC-1295 doses, mean IGF-I levels remained above baseline for up to 28 d. No serious adverse reactions were reported."

GH rose 2–10× and stayed elevated for 6 days or longer, while IGF-1 increased 1.5–3× and remained elevated for 10 days.

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults - PubMed

Subcutaneous administration of CJC-1295 resulted in sustained, dose-dependent increases in GH and IGF-I levels in healthy adults and was safe and relatively well tolerated, particularly at doses of 30 or 60 microg/kg. There was evidence of a cumulative effect after multiple doses. These data...

pubmed.ncbi.nlm.nih.gov

Acromegaly comes from sustained GH levels over the course of YEARS. Not by pinning exogenous GH which is partially pulsatile, the spike in IGF1 happens shortly after injection as actual GH only sits in the body for around 20 minutes and slowly decreases

MK667, and CJC+1295DAC, because they are GH secretagogues that keep IGF-1 elevated for 24hs AND flatten the endogenous peaks & troughs, are the closest one can get to acromegaly.

Not saying acromegaly is good, do with this information what u will

so cjcdac +mk is good or bad in your opinion. if i cant run daily gh. looking for a weekly or atleast 2x week dose substitute. either cjcdac+mk or somatrogon(longactingGh)